Senior Payroll and Accounting Specialist
Job Description
Team: Accounting
This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Senior Payroll and Accounting Specialist in United States for Spyre Therapeutics.
This role plays a critical part in ensuring the accuracy, compliance, and integrity of payroll and accounting operations within a fast-growing biotechnology environment. You will be responsible for managing end-to-end payroll processes while also supporting general ledger accounting, equity administration, and financial reporting activities. The position requires strong attention to detail and the ability to maintain precise financial records in a highly regulated, SOX-compliant setting. You will collaborate closely with HR, Finance, and cross-functional teams to ensure seamless compensation, benefits, and equity workflows. The environment is dynamic and evolving, offering exposure to both operational accounting and strategic financial processes. Your work will directly support the company’s growth, employee experience, and financial transparency.
Accountabilities:
- Manage full-cycle payroll processing, including data entry, tax withholdings, benefits deductions, and multi-state payroll compliance.
- Ensure payroll accuracy and compliance with federal, state, and local tax regulations, including filings and withholding requirements.
- Perform payroll audits and reconciliations, including payroll bank accounts and expense data validation.
- Partner with HR to administer benefits deductions such as health insurance, retirement plans, and voluntary programs.
- Maintain equity administration processes, including RSUs, stock options, and ESPP grants, vesting schedules, and exercise tracking.
- Prepare journal entries for payroll-related expenses and support monthly and quarterly financial close activities.
- Maintain SOX-compliant internal controls and documentation to ensure financial integrity and audit readiness.
- Support continuous improvement of payroll systems, workflows, and HRIS/ERP integrations.
- Bachelor’s degree in Accounting, Finance, or related field.
- 5+ years of experience in payroll and accounting, including multi-state payroll administration.
- Strong knowledge of payroll tax compliance, with experience in end-to-end payroll processing.
- Experience with payroll, HRIS, and equity platforms (e.g., Rippling, Workday, ADP, Fidelity, E*TRADE).
- Solid understanding of equity compensation structures including RSUs, NSOs, ISOs, and ESPPs.
- Strong analytical, organizational, and problem-solving skills with high attention to detail.
- Ability to handle sensitive financial and compensation data with discretion and professionalism.
- Strong communication skills and ability to collaborate across HR, Finance, and leadership teams.
- Competitive salary range of $110,000 to $130,000 USD annually, depending on experience and location.
- Equity grant opportunities and performance-based bonus eligibility.
- Comprehensive benefits package including health, welfare, and retirement plans.
- Unlimited PTO and company-wide shutdown periods for rest and recharge.
- Remote-first work environment with periodic in-person collaboration.
- Professional development opportunities in a high-growth biotech environment.
- Exposure to both operational and strategic finance responsibilities in a scaling organization.
Requirements:
Benefits:
Explore More
Date Posted
06/01/2026
Views
0
Similar Jobs
Senior Software Engineer (Tech Lead), Customer Domain Engineering - Jobgether
Views in the last 30 days - 0
View Details