Job Description
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time actionable insights to physicians providing critical information about the right treatments for the right patients at the right time.
SummaryRecent advancements in technology have made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time actionable insights to physicians providing critical information about the right treatments for the right patients at the right time.
At Tempus software and AI products are owned and developed by small autonomous teams composed of engineers designers scientists and product managers. Teams set the goals build the software deploy the code and contribute to a growing suite of capabilities that drives research and delivers advanced diagnostic and treatment improvements for our clinical partners and their patients. Tempus OS is the internal software platform that supports and connects all these teams and their products enabling them to go farther faster while safeguarding patient safety and privacy.
The RoleAs a Senior Software Engineer on the OS Ecosystem team you will act as a core technical contributor in building the foundational infrastructure that powers Tempus’ clinical research and AI capabilities. The OS Ecosystem team provides a platform that supports the full lifecycle of data and compute for a multitude of Tempus systems —from the "assembly line" of secure data ingestion cataloging and analysis to the orchestration of complex algorithms and models.
You will play a pivotal role in designing and developing systems that allow bioinformatics scientists ML and Agent developers to rapidly develop deploy and operate their solutions in a highly regulated secure and scalable environment. Focusing on data storage modeling governance and warehousing patterns and forging new connections with the latest GenAI technologies you will drive technical design and implementation to ensure our platform remains a robust foundation for cutting-edge technologies that help patients live longer healthier lives.
Responsibilities• Technical Design: Drive in-depth technical design of platform features for data modeling schema versioning and enforcing data contracts between producers and consumers using cloud object storage and data warehousing technologies ensuring alignment with functional and non-functional requirements.
• Implementation: Implement test and support backend web services and data pipelines in TypeScript and Python serving as a standard-bearer for code quality and system reliability.
• Stakeholder & Product Collaboration: Work closely with Product Managers to translate complex business requirements into technical designs ensuring clear communication and alignment with business goals and users.
• Operational Excellence: Take operational responsibility for platform systems in production as part of the team's support rotation. You will not only troubleshoot complex technical issues but also proactively monitor systems to ensure reliability and performance optimization.
• Mentorship & Best Practices: Mentor other engineers on your team fostering a culture of continuous learning and adoption of best practices in testing documentation and code review.
Qualifications• Experience: 5+ years of experience in software engineering with a focus on platform or data engineering distributed data systems or backend web services.
• Education: Bachelor's or Master's degree in Computer Science Engineering or a related field or equivalent industry experience.
• Language Proficiency: Demonstrated success in writing production backend services in TypeScript Python or similar languages with a willingness to work primarily in a Node.js and Python environment.
• Strong understanding of data structures algorithms and software design principles.
• Familiarity with relational database design and application-level operations including schema migrations. Experience with Google Spanner is a plus.
• Experience in systems monitoring and operational responsibility for platform production systems including internal user support and/or on-call duties.
• Experience working with cloud technologies (we use GCP) like GCS BigQuery and Cloud Spanner.
CHI: $110000-$160000The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California Colorado New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits which may include incentive compensation restricted stock units medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race religion color national origin gender sexual orientation age marital status veteran status or disability status.
Skills Required
- 5+ years of experience in software engineering
- Bachelor's or Master's degree in Computer Science or related field
- Experience in writing production backend services in TypeScript Python
- Strong understanding of data structures algorithms software design principles
- Experience with cloud technologies (GCP) like GCS BigQuery
What the Team is Saying










What We Do
We bring together one of the world’s largest libraries of multimodal clinical and molecular data with a robust suite of AI tools to help physicians personalize care in real time connect patients with therapies and clinical trials and enable partners to accelerate discovery and development of new treatments. With ~8 million de-identified research records and 350+ petabytes of data Tempus partners with more than half of U.S. oncologists and the majority of the top 20 global pharma companies. Our teams are pioneering work across oncology neurology psychiatry cardiology and beyond—transforming how care is delivered and therapies are developed. At Tempus every role contributes to our mission: to help each patient benefit from the experiences of those who came before. For more information visit tempus.com.
Why Work With Us
We’re looking for people who can change the world. People who question the status quo and refuse to shy away from tough problems. For builders who are never done building and the learners who are never done learning. Passionate individuals with undying curiosity who want to take on one of the greatest challenges humanity has ever faced—head on.
Gallery
Tempus AI Offices
Hybrid Workspace
Employees engage in a combination of remote and on-site work.
Most of the team follows a hybrid policy with some roles allowing for a fully remote arrangement and some roles being onsite only.











Similar Jobs
Tempus AI
Sr Manager Software Engineering
Tempus AI
Site Reliability Engineer
Tempus AI
Coordinator Tradeshow & Conference Strategy Marketing
Tempus AI
Data Scientist
Explore More
Date Posted
05/28/2026
Views
0