SR AD / Director, Clinical Development Operations Lead (CDOL/SR CDOL), Obesity

This position is posted by Jobgether on behalf of a partner company. We are currently looking for a SR AD / Director, Clinical Development Operations Lead CDOL/SR CDOL, Obesity in United States.

This role is a key leadership position within global clinical development, focused on shaping and executing operational strategies for late-phase programs in obesity and metabolic liver disease.
You will drive end-to-end clinical trial delivery with a strong emphasis on speed, quality, and value creation across complex global studies.
The position plays a central role in translating clinical development plans into executable operational strategies aligned with scientific and regulatory expectations.
You will collaborate closely with cross-functional teams including clinical operations, statistics, regulatory affairs, safety, and external partners.
The environment is highly matrixed, global, and innovation-driven, requiring strong alignment across stakeholders and geographies.
You will contribute to advancing patient-centric trial approaches, leveraging digital tools and data-driven decision-making.
This role offers high visibility and direct impact on late-stage pipeline success in a highly competitive therapeutic area.

In this role, you will lead the operational execution and strategic planning of late-phase clinical development programs in obesity and MASH.

• Lead clinical delivery and provide operational input into late-phase Clinical Development Plans
• Develop and oversee operational strategies, including timelines, country and site selection, and sourcing models
• Ensure alignment across cross-functional teams to maximize efficiency and eliminate redundancy across trials
• Drive adoption of innovative trial designs, digital technologies, and data-driven approaches
• Ensure patient-centric trial execution and sustained engagement with clinical experts and sites
• Identify feasibility risks early and define mitigation strategies, including vendor and resourcing needs
• Provide strategic direction to trial teams and ensure consistent execution against program objectives
• Collaborate with study operations teams to monitor performance and enhance trial delivery quality

Requirements:

This role requires strong expertise in global clinical development and operational leadership within complex pharmaceutical environments.

• Bachelor’s degree required; Master’s preferred in life sciences
• For Senior Associate Director level: 10+ years of clinical development or clinical operations experience
• For Director level: PhD or MD with 5+ years in therapeutic areas, or Bachelor’s/Master’s with 15+ years of clinical trial experience
• Strong experience in global clinical trial execution across multiple phases of drug development
• Experience in obesity and/or MASH strongly preferred
• Deep understanding of clinical operations within a global, matrixed pharmaceutical environment
• Proven ability to lead complex, large-scale clinical programs
• Strong strategic thinking, communication, and stakeholder management skills
• Solid knowledge of global regulatory, ethical, and compliance requirements
• Ability to work effectively across cross-functional and international teams
• Strong commitment to patient-focused innovation and ethical standards

Benefits:

• Competitive base salary ranging from $170,000 to $269,000 for CDOL level and $200,000 to $316,000 for SR CDOL level
• Eligibility for discretionary performance-based bonus
• Potential relocation support depending on role and eligibility
• Comprehensive healthcare coverage including medical, dental, and vision plans
• Retirement savings plans with employer contributions
• Paid time off, holidays, and flexible work arrangements depending on role
• Professional development and global career mobility opportunities
• Access to innovative, large-scale clinical development programs