Sr. Project Director, Evidence Development Solutions - Oncology

This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Sr. Project Director, Evidence Development Solutions - Oncology based in the United States.

This is a senior leadership opportunity for an accomplished clinical research professional to oversee complex oncology and biotechnology evidence development programs on a global scale. The role combines strategic project leadership, operational excellence, financial oversight, and client partnership to ensure the successful delivery of high-impact research initiatives. You will lead multidisciplinary teams, manage large project portfolios, and contribute to business growth while maintaining the highest standards of quality and regulatory compliance. Working in a collaborative, innovation-driven environment, you will influence organizational strategy and support the advancement of real-world evidence and clinical development programs. This position offers the opportunity to shape project delivery practices, mentor future leaders, and build lasting partnerships with global clients. The ideal candidate is a strategic leader with deep expertise in oncology clinical research and a proven record of delivering complex programs.

The Sr. Project Director will provide executive-level leadership across multiple evidence development programs while ensuring operational excellence, client satisfaction, financial performance, and regulatory compliance.

• Lead the planning, execution, and delivery of multiple global oncology and evidence development projects while ensuring alignment with client objectives and organizational strategy.
• Provide strategic leadership, guidance, and mentorship to Project Managers and multidisciplinary teams to drive high-quality project execution.
• Oversee project timelines, budgets, financial forecasting, revenue recognition, invoicing, and overall program profitability.
• Ensure projects are appropriately resourced and collaborate with cross-functional leaders to optimize staffing and team performance.
• Build and maintain strong client relationships by serving as the primary senior operational contact and trusted advisor throughout project delivery.
• Lead governance meetings, executive reviews, and project discussions while proactively resolving operational challenges and client concerns.
• Identify project risks, develop mitigation strategies, and ensure effective risk management throughout the project lifecycle.
• Ensure compliance with project plans, regulatory requirements, company procedures, and applicable international guidelines, including ICH-GCP, FDA, EMA, GDPR, and HIPAA.
• Monitor project metrics, dashboards, and performance indicators while providing accurate reports to clients and senior leadership.
• Manage external vendors and subcontractors to ensure quality, efficiency, and cost-effective project delivery.
• Contribute to business development activities, including proposal development, budget planning, client presentations, bid defenses, and conference participation.
• Drive continuous improvement initiatives by developing operational processes, SOPs, quality standards, and innovative delivery strategies.
• Support workforce planning, talent development, recruitment, onboarding, performance management, and ongoing mentoring of project management teams.

Requirements:

The ideal candidate will bring extensive leadership experience in oncology clinical research, deep knowledge of evidence development programs, and a strong ability to lead complex global projects.

• Bachelor's degree in Life Sciences, Healthcare, Business, or a related discipline; Master's or Ph.D. preferred.
• Minimum of 15–20 years of clinical research operations experience within a CRO, pharmaceutical, biotechnology, or medical device environment.
• At least 15 years of progressive project management or clinical operations leadership experience.
• Previous experience as a Project Director, Director of Clinical Operations, or similar senior leadership role is strongly preferred.
• Minimum of 8 years of people management and supervisory experience.
• Strong expertise in oncology and biotechnology clinical research is required.
• Comprehensive understanding of clinical development, evidence generation, real-world evidence (RWE), Phase II-IV studies, and global clinical research operations.
• In-depth knowledge of ICH-GCP, FDA, EMA, GDPR, HIPAA, and other applicable international regulatory standards.
• Demonstrated experience managing complex global clinical programs, budgets, resource planning, and operational strategy.
• Proven ability to lead multidisciplinary teams, mentor staff, and manage cross-functional stakeholder relationships.
• Experience supporting proposals, pricing models, business development initiatives, and client presentations.
• Strong financial management, analytical, negotiation, communication, and decision-making skills.
• Proficiency with Microsoft Office and project management tools.
• Ability to manage multiple priorities in a fast-paced, deadline-driven environment.
• Willingness to travel approximately 10% as business needs require.

Benefits:

• Competitive salary package.
• Fully remote work opportunity within the United States.
• Flexible work environment supporting work-life balance.
• Discretionary paid time off and paid holidays.
• Comprehensive medical, dental, and vision insurance.
• Health Savings Account (HSA) and Flexible Spending Account (FSA) options.
• 401(k) retirement plan with company matching contributions.
• Tuition reimbursement after 90 days of employment.
• Career growth and internal advancement opportunities.
• Employee Assistance Program (EAP).
• Telemedicine services for virtual healthcare appointments.
• Wellness program and employee discount programs.
• Adoption assistance.
• Short-term and long-term disability coverage.
• Company-paid life insurance.