Tech Jobs in SAINT LOUIS, Missouri
49,962 open positions · Updated daily
Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.
The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.
Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.
Amazing Opportunity Ob/Gyn Physician - SSM Health Depaul Hospital
Company: SSM Health
Location: Bridgeton, Missouri
Posted Jul 27, 2025
RN - Med/Surg - Part Time - Nights
Company: Mercy
Location: Washington, Missouri
Posted Jul 27, 2025
Patient Care Associate - Medical, Part Time Days
Company: Mercy
Location: Springfield, Missouri
Posted Jul 27, 2025
PCA -Patient Care Associate - Part Time (24 hrs/wk) -Days
Company: Mercy
Location: Washington, Missouri
Posted Jul 27, 2025
Busy Lake Saint Louis Family Medicine Practice seeking dedicated and compassionate NP
Company: SSM Health
Location: Lake Saint Louis, Missouri
Posted Jul 27, 2025
Nurse Technician - Med Surg 5W - 12/hrs weekly
Company: Mercy
Location: Saint Louis, Missouri
Posted Jul 27, 2025
Registered Nurse (RN) - ICU
Company: Ascension
Location: Saint Johns, FL
Posted Jul 25, 2025
Diploma from an accredited school/college of nursing OR Required professional licensure at time of hire. Serve as a primary coordinator of all disciplines for…
Physician - Pediatric Cardiology (Imaging) - Full Time - SLUCare Physician Group
Company: SSM Health
Location: Saint Louis, Missouri
Posted Jul 27, 2025
Patient Care Associate-PCA (Non-Exempt)
Company: Mercy
Location: Saint Louis, Missouri
Posted Jul 27, 2025
Handyman / Multi Skilled Carpenter
Company: Ace Handyman Services Jacksonville
Location: Saint Johns, FL
Posted Jul 26, 2025
Current and valid driver’s license. You will work out of your home on your choice of a full time or part-time basis, using your own truck or van to travel to…