Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

QC Investigations - Scientist II

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 12, 2025

Thermo Fisher Scientific is seeking a Quality Engineer/Scientist II in St. Louis, MO. The role involves leading multiple investigations, maintaining a high record closure rate, and assisting more junior investigators. The ideal candidate will have a minimum of an Associate's degree, 3+ years in a GMP regulated environment, and experience with TrackWise and TapRooT. Key responsibilities include conducting RAPID meetings, using TrackWise software, and supporting compliance culture initiatives. The company offers competitive remuneration, healthcare benefits, and a supportive work environment.

Teller West St. Paul, MN

Company: Wells Fargo

Location: Saint Paul, MN

Posted Jan 12, 2025

Wells Fargo emphasizes a meaningful career with competitive salary, robust benefits, and programs for work-life balance. They ranked in the top three on the 2024 LinkedIn Top Companies List. The company is seeking a Teller in their Consumer, Small & Business Banking division, offering career growth opportunities. The role involves customer engagement, transaction processing, and relationship building. Required qualifications include customer interaction experience, while desired qualifications encompass customer service, tech education, and team collaboration skills.

Cook II

Company: Sodexo

Location: Saint Paul, MN

Posted Jan 12, 2025

Sodexo is seeking a Cook II with 3-4 years of experience for a part-time on-call position at HAZELDEN FELLOWSHIP CLUB. The role involves preparing and creating nutritious dishes, reducing food waste, and providing excellent customer service. The company offers a flexible work environment, ongoing training, and a comprehensive benefits package including paid time off, medical, dental, vision, tuition reimbursement, and 401k. Sodexo values diversity and inclusion, fostering an environment where all employees are respected and valued.

HIV Virology Regional Medical Scientific Director - MO/KS/IA/NE/SD/ND (Remote)

Company: Merck

Location: St. Louis, MO

Posted Jan 12, 2025

The Regional Medical Scientific Director (RMSD) role is a credentialed position requiring a PhD, PharmD, DNP, or MD. The RMSD engages in scientific exchange, clinical research, scientific congress support, and gathering scientific insights. They liaise between the scientific community and the company, enhancing understanding of scientific foundations and goals for various trials. The role involves developing professional relationships with Scientific Leaders, addressing scientific questions, and ensuring access to medical and scientific information. The RMSD also contributes to clinical research, scientific congresses, and provides feedback on medical or scientific needs. Key qualifications include clinical or research experience in assigned therapeutic areas, at least 3 years of therapeutic area experience in HIV or Infectious Diseases, and strong communication and networking skills.

Security Architect

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 12, 2025

Edward Jones is seeking a Security Architect to lead security considerations in their technology transformation efforts, particularly in cloud environments. The role involves embedding with the business portfolio, identifying risks and threats, advocating for a security-by-design approach, and participating in proof-of-concept efforts for new SaaS and IaaS applications. The company offers a comprehensive compensation and benefits package, including medical, dental, vision, disability, life, and AD&D coverage, a 401k retirement plan, and various tax-advantaged accounts. The ideal candidate will have at least 8 years of cybersecurity experience, expertise in architecting secure systems, and strong communication skills. Hands-on experience with Microsoft Azure and understanding of financial sector regulations are beneficial. Edward Jones is a Fortune 500 company that values its associates and is committed to innovation, flexibility, and inclusivity.

Analyst II - Branch Compensation- Finance

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 12, 2025

Edward Jones is seeking a full-time Branch Compensation professional to handle timely and accurate payment of Financial Advisor compensation, including commissions, bonuses, and other incentives. The role involves working in a fast-paced, complex environment, managing multiple key processes, and collaborating with the department leader. Key responsibilities include administering compensation programs, executing internal controls, identifying process improvements, and providing excellent customer service to Financial Advisors. The compensation package includes medical, dental, vision, disability, life insurance, retirement plans, and paid time off. The ideal candidate has a bachelor's degree, 1-2 years of related experience, advanced Excel skills, and strong communication and organizational abilities.

Family Medicine Physician - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Jan 12, 2025

Mosaic Life Care, a physician-led healthcare system, is seeking a BC/BE Family Medicine physician for a flexible 4.5-day workweek in St. Joseph, MO. The position offers a supportive environment with resources like an integrated EHR, collaboration with specialists, and a collegial setting with six physicians, eight APPs, and a dedicated team. Benefits include a competitive salary, bonuses, student loan assistance, comprehensive insurance, CME reimbursement, a 401(k) plan, and relocation assistance. The practice covers newborn through geriatric care, with no ER or OB duties, and full backup from subspecialties.

Sr Customer Service Representative, Saint-Herblain

Company: Thermo Fisher Scientific

Location: Saint-Herblain, France

Posted Jan 12, 2025

The job description involves managing commercial files within the LPD France organization, ensuring client satisfaction. Key responsibilities include supporting the direct sales force and national distributors through administrative management of commercial files, handling client inquiries, and processing orders from pre-sale to post-sale. The role also involves collaborating closely with all group services, optimizing client relationships, and having a good command of English. Previous client service or commercial experience is required, with a preference for SAP and Salesforce knowledge. The successful candidate will be team-oriented, customer-focused, dynamic, and available.

Cook - St. Louis Anheuser Busch

Company: Aramark

Location: St. Louis, MO

Posted Jan 12, 2025

Aramark is seeking a passionate Cook to join their team. The role involves preparing a variety of food according to standardized recipes, using a range of cooking methods, and maintaining food safety. The Cook will also be responsible for setting up their workstation, cleaning and sanitizing equipment, and providing excellent customer service. Aramark values employee development and offers opportunities for skill enhancement. The ideal candidate should have prior cooking experience, knowledge of food preparation principles, and food safety regulations.

Assistant Manager, Merchandising - St Louis Galleria

Company: Gap Inc.

Location: St. Louis, MO

Posted Jan 12, 2025

Gap is an iconic American brand that values optimism and customer experience. The company seeks an Assistant Manager to drive sales growth, lead a high-performing team, and deliver results through a customer-centric mindset.

Shift Technician

Company: Diageo

Location: Saint Andrews, United Kingdom

Posted Jan 12, 2025

Diageo is offering a permanent position for a Shift Technician at their Bio-Energy plant in Cameronbridge, Scotland. The role involves monitoring and maintaining various plants, ensuring optimum efficiency and reliability. The technician will also be responsible for routine inspections, reporting anomalies, and maintaining a safe working environment. The job is crucial in Diageo's efforts to achieve net zero carbon by 2030, utilizing organic by-products from whisky making as renewable energy sources. The role requires an HNC in engineering or equivalent experience, strong analytical skills, and the ability to work in a 24/7 environment.

Sales Account Orchestrator - CPG

Company: Siemens Digital Industries Software

Location: St. Louis, MO

Posted Jan 12, 2025

Siemens Software offers a role as an Entry level local Sales Account Orchestrator, responsible for managing a small number of accounts and meeting sales revenue targets. The position involves account planning, team orchestration, prospecting, opportunity management, sales administration, analytics, mentoring, and knowledge sharing. Siemens Software promotes flexibility, diversity, and offers competitive compensation with benefits. The company is dedicated to equality and welcomes applications reflecting community diversity.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

Related Pages