Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Occupational Therapist - Mercy Springfield- Full Time Acute Therapy

Company: Mercy

Location: Springfield, Missouri

Posted Jan 12, 2025

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy encourages innovation and collaboration, and is committed to delivering excellent care. They are currently offering a $10,000 sign-on bonus, though with certain restrictions.

Lead Trading Enablement Assistant

Company: Wells Fargo

Location: St. Louis, MO

Posted Jan 12, 2025

Wells Fargo is seeking a candidate with 6+ years of Trading Enablement experience or equivalent. The role involves delivering exceptional service, educating customers on products, identifying process improvement opportunities, and collaborating with peers. Required qualifications include FINRA Series 7 and 63 or 66 examinations, trading experience, and strong communication skills. The job expects a hybrid schedule and offers opportunities for growth and development.

Maternity RN Case Manager - Remote in Jefferson County, MO and surrounding areas

Company: UnitedHealth Group

Location: St. Louis, MO

Posted Jan 12, 2025

UnitedHealthcare is seeking a qualified RN with OB or NICU experience for a telephonic Case Manager role. The position involves providing evidence-based education for healthy pregnancy outcomes, coordinating care for high-risk maternity members, and making outbound calls to assess members' health status. The RN will also identify gaps in treatment plans, educate members on disease processes, and encourage healthy lifestyle changes. The role requires proficiency in Microsoft Office Suite, strong communication skills, and the ability to work independently and as part of a team. The company offers competitive pay, comprehensive benefits, and opportunities for growth. UnitedHealthcare is committed to diversity, equity, and environmental sustainability, and is an Equal Employment Opportunity employer.

Field Service Engineer ,

Company: Thermo Fisher Scientific

Location: Saint-Égrève, France

Posted Jan 12, 2025

Thermo Fisher Scientific is seeking a professional with a Bachelor's Degree or equivalent in a relevant field and 2-5 years of experience in maintaining in vitro diagnostic systems. The role involves performing preventive maintenance, troubleshooting, and resolving complex failures on protein diagnostic products. The candidate will travel to customer sites, collaborate with the FSE team, and manage spare parts stock. Essential qualities include strong team spirit, excellent communication skills, and problem-solving abilities. The mission is to contribute to making the world healthier, cleaner, and safer.

Procurement Partner

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 12, 2025

The Procurement Partner role contributes to developing multi-year strategies and business plans for the division, driving execution of the Procurement vision. The individual partners with the divisional operations leader, focusing on strategy, execution, and implementation. The role involves establishing goals, translating objectives to category management teams, delivering on key objectives, coordinating long-range strategies, partnering with Category Managers and R&D, driving value improvements, and ensuring alignment with business colleagues. The role also involves technical responsibilities such as collecting supplier capability requirements, gathering business requirements, driving compliance, and leadership responsibilities such as aligning Procurement strategy with the Divisional Leadership team and supporting division initiatives.

Screener/Venipuncture- South Central Region

Company: Labcorp

Location: Saint George, UT

Posted Jan 12, 2025

Labcorp is seeking medical professionals to provide testing services at events. The company offers comprehensive training, biometric screenings, and excellent customer service. Medical credentials are required, and candidates must have experience working in a healthcare setting.

Senior Team Leader, Financial Crimes

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 12, 2025

Edward Jones is a financial services firm that prioritizes client relationships and service. The company offers a comprehensive benefits package and is committed to creating a positive work environment. The job description outlines the responsibilities of an Investigator in the Financial Crimes Program, which includes leading a team, developing systems, and ensuring compliance with regulations.

Financial Advisor - Edward Jones Connection

Company: Edward Jones

Location: St. Louis, MO

Posted Jan 12, 2025

Edward Jones is a financial services firm that prioritizes client relationships, with a focus on service and operations. The Branch Development division hires, trains, and supports branch teams to deliver an ideal client experience. The Edward Jones Connection (EJC) department serves smaller clients remotely, working closely with local branch teams. Key responsibilities include acting as a Financial Advisor, providing excellent client service, and ensuring high-level customer service. The role requires current Series 7 and 66 licenses, a business-related bachelor's degree, and strong communication and computer skills.

Store Associate

Company: CVS Health

Location: Missouri City, TX

Posted Jan 12, 2025

CVS Health is seeking Retail Store Associates to join their team, emphasizing a human-centric approach to healthcare. The role involves providing excellent customer service, managing cashier duties, maintaining the sales floor, supporting store activities, and assisting in the pharmacy. The company offers competitive pay, comprehensive benefits, and opportunities for career growth. No prior retail experience is required, but a high school diploma is preferred.

Nurse Practitioner - Statewide Traveler - HouseCalls - Missouri

Company: UnitedHealth Group

Location: St. Louis, MO

Posted Jan 12, 2025

Optum is hiring a Nurse Practitioner for its HouseCalls team in St. Louis, MO. The role involves conducting in-home assessments, performing evidence-based practice screenings, and educating members on health topics. The position offers flexible scheduling, no on-call duties, and comprehensive compensation including a base salary and incentives. Travel across Missouri is required, with all expenses covered.

Sr Manager, Finance

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Jan 12, 2025

Thermo Fisher Scientific is seeking a Sr. Manager of Finance for their Large Molecule business unit within the Pharma Services Group. The role involves leading finance activities, partnering with the commercial team, and driving growth and profitability. Key responsibilities include financial analysis, reporting, planning, and forecasting. The ideal candidate should have an undergraduate degree in Finance or related field, at least 10 years of finance experience, and strong leadership and analytical skills. Thermo Fisher Scientific offers competitive benefits and a culture that values integrity, intensity, involvement, and innovation.

Data Center Technician

Company: Google

Location: Saint-Michel-sur-Orge, France

Posted Jan 12, 2025

The job posting is for a Technical Infrastructure role at Google, responsible for deploying and operating new data center infrastructure, troubleshooting and diagnosing issues, maintaining data security, and performing preventative maintenance on equipment. The ideal candidate should have a Bachelor's degree, experience in diagnosing and troubleshooting operating systems, computer/server hardware, or networking protocols, and the ability to lift heavy equipment. Preferred qualifications include certification in Google's IT Support Professional Certificate program, experience in a data center or network operation center, and the ability to collaborate and adapt to changes in a dynamic work environment.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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