Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

A Facility in MO Is Seeking a Psychiatrist GMS# JOB-3007935

Company: Global Medical Staffing

Location: Missouri

Posted Dec 23, 2024

The text describes a job opportunity in General/Adult Psychiatry in Missouri. The company, a part of the CHG Healthcare family, offers competitive compensation, pre-paid travel and housing, and malpractice insurance. They have a global reach, placing doctors in various countries including the US, Australia, New Zealand, and more. The company prides itself on personal service, speed, and attention to detail. They also support the Making a Difference Foundation, providing physicians opportunities to help in needy areas.

Missouri Facility Is Searching for a Locums Maternal Fetal Medicine Physician/Perinatologist WBY# JOB-3007660

Company: Weatherby Healthcare

Location: Springfield, Missouri

Posted Dec 23, 2024

Weatherby Healthcare, founded in 1995, offers locum tenens staffing for various medical professionals. They provide support for assignments in large healthcare networks, hospitals, and clinics across the US. The current opening is for a Maternal Fetal Medicine specialist in Springfield, Missouri. Benefits include paid malpractice insurance, pre-paid travel and housing, competitive compensation, and 24-hour consultant access.

CRNA - $300K + $60K Sign-on. Flexible schedule. Great benefits, Great Cases

Company: NorthStar Anesthesia

Location: Joplin, Missouri

Posted Dec 23, 2024

NorthStar Anesthesia, a rapidly expanding provider of anesthesia services in the US, is seeking passionate CRNAs to join their team in Joplin, MO at Mercy Hospital. The role offers a competitive salary up to $300,000/year, a $60K sign-on bonus, generous PTO, flexible scheduling, and comprehensive benefits. NorthStar values collaboration, innovation, and excellence in patient care, and is committed to professional development and work-life balance. The facility is well-equipped and offers a diverse case mix. New grads and SRNA's are encouraged to apply.

CRNA - $210K total comp, $30K sign-on. No Call/Weekends! 13 weeks PTO! Flexible schedule.

Company: NorthStar Anesthesia

Location: Blue Springs, Missouri

Posted Dec 23, 2024

NorthStar Anesthesia is inviting passionate CRNAs to join their nationwide expansion. They offer industry-leading compensation, benefits, and opportunities for growth. The role is for a CRNA at St. Mary's Medical and Surgery Center in Blue Springs, Missouri, with a great quality of life. The compensation package includes a $200,000 salary, $10,000 yearly bonus, incentives, stipends, and a $30K sign-on bonus. They provide flexible scheduling, generous PTO, and comprehensive insurance coverage. NorthStar values excellence in patient care and fosters leadership and professional development.

Urgent Care Physician (MD/DO)

Company: GoHealth Urgent Care

Location: Springfield, Missouri

Posted Dec 23, 2024

Mercy-GoHealth Urgent Care in Springfield, MO is recruiting a Physician for full-time, part-time, or per diem positions. The job offer includes competitive compensation, advanced facilities, and supportive staff. The organization emphasizes quality care, patient satisfaction, and professional growth. They provide bonuses based on productivity and patient satisfaction scores.

Physician - Pain Management - Full Time - Jefferson City, MO.

Company: SSM Health

Location: Jefferson City, Missouri

Posted Dec 23, 2024

SSM Health St. Mary's Hospital is recruiting a full-time Pain Management Physician. The role covers both inpatient and outpatient needs with a schedule of Monday-Friday, 8:00AM-5:00PM. The hospital offers an excellent onboarding process, two-year guarantee salary, and comprehensive benefits. It's part of a fully integrated system using Epic EMR for improved care coordination. Located in Jefferson City, Missouri, the hospital serves patients with a wide range of services and is committed to equal employment opportunity.

Applications Engineer, Senior

Company: Barry-Wehmiller

Location: Minneapolis–Saint Paul, MN

Posted Dec 23, 2024

Machine Solutions is a premier provider of advanced equipment and services for the medical device, biopharmaceutical, and blood and plasmacollection industries. They offer proprietary mechanical solutions for complex process testing and device design challenges, with equipment that has become the industry standard for stent crimping, balloon catheter pleating, and folding. The company is also a pioneer in radio frequency technology, developing advanced technology for thermal forming, molding, and welding plastic for medical manufacturing, biopharmaceutical, and blood and plasmaprocessing applications. Machine Solutions is privately owned by BW Forsyth Partners, a BarryWehmiller company, which blends BarryWehmiller's unparalleled legacy of value creation and people-centric culture development with keen investing experience to help companies realize their true potential.

A Facility in MO Is Searching for a Locum Tenens Psychiatrist CPH# JOB-3007936

Company: CompHealth

Location: Missouri

Posted Dec 23, 2024

CompHealth offers true opportunities for locum assignments, providing expert guidance and tailored support. They negotiate better pay, arrange complimentary housing and travel, and simplify credentialing processes. With a team of 1,000 employees across the nation, they ensure excellent customer service.

Physical Therapist

Company: Mercy

Location: Creve Coeur, Missouri

Posted Dec 23, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy encourages innovation and collaboration, providing opportunities for pioneering new models of care and transforming healthcare through advanced technology. They are committed to inclusivity, welcoming minorities, females, disabled, and veterans.

Echo Technologist (Non-Exempt)

Company: Mercy

Location: Cape Girardeau, Missouri

Posted Dec 23, 2024

Mercy offers careers in healthcare, particularly in echocardiography procedures, with a focus on compassionate care and exceptional service. They provide comprehensive benefits, including health coverage, tuition reimbursement, and retirement funds. Mercy values professionals who are skilled, compassionate, and committed to delivering excellent care. The role involves maintaining patient rights, confidentiality, and performing echocardiography procedures. The ideal candidate should have relevant certifications and be physically capable of long walks and patient assistance.

Clinical Pharmacy Specialist - Oncology - FT

Company: Mercy

Location: Saint Louis, Missouri

Posted Dec 23, 2024

Mercy is inviting applications for an Oncology Pharmacy position, requiring a PGY-2 residency in oncology and a PharmD degree. The role involves providing safe and effective drug therapy, serving as a drug information resource, and aligning with Mercy's mission and values. Mercy offers comprehensive benefits and encourages a collaborative, compassionate work environment focused on innovation and excellent care.

Real and Reporting Analyst

Company: CVS Health

Location: Minneapolis–Saint Paul, MN

Posted Dec 23, 2024

The text describes a role at CVS Health that involves bringing human-centric health care to every moment of a patient's life. The role requires a deep understanding of healthcare quality renewals, client advocacy, and account management. The position also involves utilizing various data systems, medical terminology knowledge, and strong communication skills. The company offers competitive benefits and a positive work environment.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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