Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Supervisor, QC - Weekends

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Dec 19, 2024

The QC Analytical Supervisor position at Thermo Fisher Scientific in St. Louis, MO, involves managing a weekend team of laboratory analysts and data reviewers. Key responsibilities include scheduling, authoring and approving laboratory documents, supporting engineering tasks, conducting compliance walkthroughs, and leading staff. The role requires a Bachelor's degree in a biological science, 5+ years of GMP experience, and proficiency in MS Office. The company offers competitive remuneration, benefits, and a mission-driven culture focused on health, cleanliness, and safety.

Clinic PA/NP Wanted in Western Missouri - Sign-on/Relocation! CPH# JOB-3003649

Company: CompHealth

Location: El Dorado Springs, Missouri

Posted Dec 19, 2024

A clinic in El Dorado Springs, Missouri, is seeking a Physician Assistant or Nurse Practitioner with at least 1 year of experience. The role involves providing primary care and walk-in services in a rural community, working independently, and performing office procedures. The clinic offers a base salary, daily volume bonus, and annual quality bonus. Sign-on and relocation are negotiable, and full benefits are provided. The clinic is NHSC-certified, qualifying for loan repayment. The town is family-friendly with a low cost of living, safe neighborhoods, and access to outdoor activities. CompHealth, a leading healthcare staffing company, is facilitating the recruitment process.

Staff Scientist, Manufacturing Sciences

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Dec 19, 2024

Thermo Fisher Scientific Inc. is seeking a Staff Scientist in Manufacturing Sciences for their St. Louis, MO location. The role involves optimizing manufacturing processes, providing technical leadership, collaborating with cross-functional teams, fostering continuous improvement, offering technical support, managing projects, mentoring junior scientists, and ensuring regulatory compliance. The ideal candidate should have a degree in Chemical Engineering, Biomedical Engineering, Biochemistry, or a related field, with experience ranging from a Bachelor's to a Ph.D., along with proven experience in process development, validation, and regulatory compliance. The company offers a competitive salary, growth opportunities, and a collaborative work environment.

Personal Banker Roving Monticello, Buffalo, Saint Cloud, Sauk Rapids Branches

Company: Wells Fargo

Location: Saint Michael, MN

Posted Dec 19, 2024

Wells Fargo is seeking an Associate Roving Personal Banker (SAFE) for their National Branch Network. The role involves providing support across various branch locations, delivering exceptional customer experience, and assisting customers with financial needs. The company is recognized as a top workplace for career growth. Required qualifications include customer service experience and SAFE registration. The position offers a competitive salary, robust benefits, and opportunities for career advancement.

Cashier/Food Service Worker

Company: Sodexo

Location: St. Louis, MO

Posted Dec 19, 2024

Sodexo is seeking a part-time Cashier/Food Service Worker for varying shifts at Saint Louis University. The role involves operating a cash register, assisting in food service setup and serving, and supporting the retail operation. Successful candidates should be team-oriented, adaptable, reliable, and promote a healthy/safe work environment. Sodexo offers a flexible work environment, training opportunities, and comprehensive benefits including paid time off, medical, dental, vision, tuition reimbursement, and more. The company values diversity and inclusion, fostering an environment where all employees are respected and valued.

Seasonal Retail Sales Associate - West County Ctr

Company: Gap Inc.

Location: St. Louis, MO

Posted Dec 19, 2024

Gap, an iconic American brand, is seeking a Brand Associate to join their team. The role involves providing excellent customer service, educating customers about products, and driving sales through suggestive selling. The ideal candidate is a good communicator, customer-focused, passionate about retail, and a problem solver. They should be flexible with their schedule and comfortable using retail technology. Gap Inc. is committed to diversity and inclusion, having been recognized by Forbes as one of the World's Best Employers and one of the Best Employers for Diversity.

Business Applications Solution Developer

Company: Edward Jones

Location: St. Louis, MO

Posted Dec 19, 2024

Edward Jones, a Fortune 500 company, focuses on client-centric operations. The Operations division aims to enhance client and branch experience through key phases like account opening, trade settlement, and tax reporting. The Solutions Developer role involves designing, developing, and implementing reporting solutions, creating web-based applications, and maintaining extensive knowledge of enterprise systems. The role requires a Bachelor's degree, 4+ years of software development experience, and expertise in SQL, Java, Linux, COBOL, HTML, or WebFocus. The company offers comprehensive benefits including medical, dental, vision, disability, life insurance, 401k, and flexible spending accounts.

Pharmacy Technician

Company: CVS Health

Location: Missouri City, TX

Posted Dec 19, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing pharmacy workstations, and ensuring regulatory compliance. New hires must complete a training program and meet state board of pharmacy requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, and well-being programs.

Middle GDATM Software Engineer

Company: Leidos

Location: St. Louis, MO

Posted Dec 19, 2024

The Intelligence Group at Leidos is seeking an Exploitation Specialist/GDAT Software Engineer for a role in St. Louis, Missouri. The position involves supporting the customer in modernizing applications for production operations, focusing on minor improvements in software functionality for routine maintenance. The role requires a BA degree with 4-8 years of relevant experience or a Master's degree with 2-6 years of experience. Key skills include User Interface Design, Web Data Hosting, .NET Visual Basic programming, Window Desktop application development, and Software Test Engineering. Familiarity with Amazon CLI and Cloud Access Portal is a plus. The role involves supporting the GDAT-M application, which is crucial for the customer's Geopositioning and validation of National products.

Value Chain Product Lead (Global Supply Chain Management)

Company: Merck

Location: Saint-Étienne-du-Rouvray, France

Posted Dec 19, 2024

The text describes a job opportunity for a Value Chain Product Lead (Global Supply Chain Management) in a global company. The role involves strategic product planning, cross-divisional alignment, and supply chain design and optimization, with a focus on Launch Excellence. The successful candidate will develop and execute product and long-term supply strategies for the Aqua business portfolio, collaborate with various departments, and lead Launch Supply Execution teams. The role requires a degree in Engineering, Science, or Supply Chain Management, extensive international experience, and a proven track record in leading cross-functional teams. The company offers a dynamic global environment with opportunities for personal development and competitive benefits.

Radiology Intern I (Non-Exempt)

Company: Mercy

Location: Cape Girardeau, Missouri

Posted Dec 19, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with opportunities for growth and innovation. The X-Ray Technologist position involves performing diagnostic radiology procedures under supervision, ensuring optimal image quality, and providing personalized care to patients of all ages. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They seek candidates with a positive outlook, strong advocacy, and a commitment to delivering excellent care.

Non-Interventional Cardiologist Needed in a Top Arkansas Practice

Company: Curare Physician Recruiting

Location: Springfield, Missouri 65801

Posted Dec 19, 2024

This job opportunity in Springfield, Missouri offers a chance to establish a new Cardiology program in a beautiful, low-crime community with excellent schools and affordable living. Benefits include a 4-day work week, extensive support, competitive salary, and generous bonuses. The area boasts abundant outdoor recreational activities and natural resources.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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