Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Network Engineer

Company: Quetica, LLC

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Quetica is seeking a full-time network resource to support and configure Cisco switches, Wireless ASA, VPN, CheckPoint firewalls, Palo Alto, and F5 load balancers. The position is hybrid, with 2 days per week in the office at 1430 Maryland Ave E, Saint Paul, MN 55106. Desired skills include 3+ years of network hardware and software experience, expertise in Cisco, TCP/IP, network test equipment, and more. The role involves network system administration, service ticket management, and document development. Interviews will be conducted remotely via Microsoft Teams.

RN - Weekends Ortho Neuro Full Time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Dec 05, 2024

The job posting offers a range of incentives including a sign-on bonus of up to $20,000 for new graduates and $5,000 for those with 1+ years of RN experience. It also provides education assistance such as loan forgiveness and tuition reimbursement. Additional benefits include relocation assistance, weekend and shift differentials, comprehensive insurance, and retirement funds. The position is in a Surgical Unit focusing on adult post-operative orthopedic traumas and Neurosurgery, offering opportunities for skill development.

MO Facility Is Searching for a Locums Radiation Oncologist WBY# JOB-3001412

Company: Weatherby Healthcare

Location: Missouri

Posted Dec 05, 2024

Weatherby Healthcare, a leading locum tenens staffing company, is offering a Radiation Oncology position in Missouri. The role involves 3 consults and 8 follow-ups per week, with paid malpractice insurance, pre-paid travel, and housing expenses. The company provides competitive compensation and 24-hour access to a consultant. Weatherby Healthcare is a charter member of NALTO and has been in operation since 1995.

Nurse Practitioner (NP) Family Medicine

Company: Community Health Systems

Location: Moberly, Missouri

Posted Dec 05, 2024

Moberly Regional Medical Center is seeking a Family Nurse Practitioner for their rural health clinic. The position offers a competitive salary, commencement bonus, and other benefits. Moberly, known as the 'Magic City', is located 36 miles north of Columbia, MO and is home to two colleges. It boasts an extensive park system with recreational areas, a water park, and sports facilities. The city also has a strategic relationship with the University of Missouri-Columbia.

Sr. Java Developer

Company: Quetica, LLC

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Quetica is seeking a senior contractor developer to modernize the CLiCS application used by Nutrition Program Services NPS. The role involves rewriting several application screens and underlying screen technology using the Spring MVC framework. The project aims to increase user satisfaction, improve viability, sustainability, and maintainability, and ensure compliance with USDA regulations. Desired skills include 5 years of experience with Java web applications, 3 years with GroovyGrails, 2 years of software architecture, and 5 years of experience developing software.

Psychiatrist Is Wanted for Locums Help in MO WBY# JOB-2997164

Company: Weatherby Healthcare

Location: Missouri

Posted Dec 05, 2024

Weatherby Healthcare is a leading expert in locum tenens staffing for physicians, physician assistants, and nurse practitioners. The company has established itself as a trusted partner for top healthcare providers nationwide, offering competitive compensation, flexible scheduling, and access to experienced consultants.

Urgent Care Physician Is Needed for Locums Assistance in MO CPH# JOB-3001794

Company: CompHealth

Location: Springfield, Missouri

Posted Dec 05, 2024

CompHealth is a healthcare staffing company that simplifies the locums process. They offer services such as job search, credentialing, housing arrangements, travel coordination, and better pay negotiation. The company is currently seeking an Urgent Care specialist for a position in Springfield, Missouri. The role involves treating both pediatric and adult patients, performing procedures like suturing, wound care, and I&D, and requires BLS, DEA, and state license. CompHealth provides comprehensive malpractice coverage and a user-friendly online portal for assignment details.

Physician - IM Hematology/Oncology - Full Time Academic - SLUCare Physician Group

Company: SSM Health

Location: St. Louis, Missouri

Posted Dec 05, 2024

SSM Health is seeking applicants for a full-time appointment in the Division of Hematology and Oncology at SLUCare Physician Group, a member of SSM Health. The position includes patient care, teaching, and clinical research. SLUCare physicians educate the next generation of healthcare professionals and provide exceptional medical services to patients. The company has partnered with SSM Health for decades and is committed to equal employment opportunity.

A Facility in Missouri Seeks a Locums Radiologist WBY# JOB-3002160

Company: Weatherby Healthcare

Location: Joplin, Missouri

Posted Dec 05, 2024

Weatherby Healthcare, a leading locum tenens staffing company, is offering a General Radiology position in Joplin, Missouri. The assignment requires BC or BE, MQSA certification, DEA, and mammography credentials. Benefits include competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, specializes in filling temporary staffing gaps in healthcare networks nationwide.

Operational Manager / 245D Designated Manager

Company: Dungarvin

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Dungarvin is a national company with a family-like atmosphere, offering top-notch community-based support to individuals with intellectual and developmental disabilities, mental health challenges, and significant medical needs. They provide exceptional assistance, starting salary of $69,000 annually, 401k plan, free life insurance and long-term disability, job mobility options, PTO that increases with tenure, pet insurance, medical, dental, and vision coverage, supplemental insurance, flex spending and HSA accounts, mileage reimbursement, and a referral bonus program. The role requires strong leadership, organizational, and communication skills to ensure high-quality services and achieve organizational goals.

Urgent Care Physician Is Needed for Locums Coverage in MO WBY# JOB-3001718

Company: Weatherby Healthcare

Location: Springfield, Missouri

Posted Dec 05, 2024

Weatherby Healthcare is offering a locum tenens opportunity in Urgent Care in Springfield, Missouri. The position requires BC or BE, BLS, and the ability to handle 3-4 patients per hour with various procedures. Weatherby provides competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. The company, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Physical Therapist

Company: Mercy

Location: Dexter, Missouri

Posted Dec 05, 2024

Mercy is a top employer offering comprehensive benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They value compassionate care and professionalism, providing opportunities for growth and innovation. Mercy seeks Physical Therapists with Bachelor, Master, or Doctorate degrees, current licensure, and preferred experience in adult and geriatric care. They emphasize a positive work environment and commitment to excellent care.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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