Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Oncology Opening in Joplin, MO!

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Dec 05, 2024

Archway Physician Recruitment is seeking a full-time BE/BC Oncologist/Hematologist for a hospital-employed position in Joplin, MO. The successful candidate will join a group of five Oncologists and one Radiation Oncologist in an established and busy practice. The position offers a high number of patient visits per day, teaching opportunities, and a competitive compensation package including a one-year guarantee, wRVU production model, and full benefits. Joplin, MO, is described as a city rich in history and community spirit with a vibrant arts scene, historic downtown, and proximity to Route 66.

Senior Systems Engineer, Oracle EPM

Company: Block

Location: St. Louis, MO

Posted Dec 05, 2024

Block is a company built on the foundation of many blocks, all united by the same purpose of economic empowerment. They have a diverse team of professionals working across various business groups and time zones to develop inclusive people policies, forecast finances, provide legal counsel, and safeguard systems. They are seeking a Senior Systems Engineer with deep technical and functional expertise in Oracle EPM Planning to drive the success of their financial planning and analysis initiatives.

Occ Med in the Ozarks

Company: Curare Physician Recruiting

Location: Joplin, Missouri 64804

Posted Dec 05, 2024

The Curare Group is offering a high-volume occupational medicine position in Joplin, Missouri. The role involves treating work-related injuries and conducting physicals, with a competitive compensation package including a residency stipend, start bonus, and relocation assistance. The location offers a low cost of living, outdoor activities, a vibrant restaurant scene, and a new performing arts center. The company, Curare, has been a leading player in physician recruitment for 25 years, providing comprehensive support from CV writing to contract negotiation.

Locums Position in MO for Internal Medicine Physician CPH# JOB-3001309

Company: CompHealth

Location: Ferguson, Missouri

Posted Dec 05, 2024

CompHealth offers a wide range of locum tenens opportunities in Internal Medicine, tailored to individual needs and career phases. They provide expert guidance, negotiate better pay, arrange housing and travel, and simplify credentialing. The job in Ferguson, Missouri involves direct patient care, with an average of 14 patients per day.

Orthopedics in the Ozarks

Company: Curare Physician Recruiting

Location: Joplin, Missouri 64804

Posted Dec 05, 2024

Curare Group offers a balance between professional career change and an enjoyable lifestyle. They provide customized job search services, support from Placement Specialists, and access to top health systems and private practices.

Permanent Gastroenterologist (GI) Needed at a Nonprofit Clinic Located South of Orlando, Florida CPH# JOB-2997538

Company: CompHealth

Location: Saint Cloud, Florida

Posted Dec 05, 2024

CompHealth, a leading healthcare staffing agency since 1979, is offering a Gastroenterology position in Saint Cloud, Florida. The location is conveniently close to Orlando and provides a great work-life balance with a Monday through Friday schedule and minimal call. Benefits include a starting bonus paid over 2 years, loan repayment, malpractice coverage, life insurance, medical benefits, and a retirement package. CompHealth specializes in matching providers with suitable jobs based on their lifestyle preferences, and their services are free for the candidates. They assist with salary negotiation, interview coordination, license help, and have experienced support teams.

A Facility in Missouri Is Searching for a Locum Tenens Obstetrics/Gynecologist WBY# JOB-2999953

Company: Weatherby Healthcare

Location: Lee's Summit, Missouri

Posted Dec 05, 2024

Weatherby Healthcare offers a supportive locum tenens lifestyle for OB/GYN physicians in Lee's Summit, Missouri. The assignment includes competitive compensation, pre-paid travel and housing expenses, and malpractice insurance. Weatherby, a leading expert in locum tenens staffing since 1995, provides 24-hour access to consultants and handles credentialing, DEA, and NALTO membership. The position requires weekend call, 200 cases per month, and specific certifications.

RN Nurse Opportunities - Mercy Jefferson Hospital

Company: Mercy

Location: Festus, Missouri

Posted Dec 05, 2024

Mercy Hospital Jefferson offers various incentives for experienced and new RNs, including sign-on bonuses, loan forgiveness programs, and tuition reimbursement. They provide numerous benefits such as shift differential pay, annual merit increases, health/dental/vision insurance, and paid parental leave. Mercy emphasizes a supportive community and career growth opportunities, having been named one of 'Modern Healthcare Magazine's Top 100 Places to Work'.

ENT / Otolaryngologist Opportunity in Central Florida CPH# JOB-3001775

Company: CompHealth

Location: Saint Cloud, Florida

Posted Dec 05, 2024

CompHealth, a leading healthcare staffing company since 1979, offers comprehensive support for Otolaryngology professionals seeking employment. They assist with contract negotiation, including pay, benefits, and incentives, and provide sign-on bonuses, relocation assistance, and loan repayment. The company has a nationwide network, connecting professionals to various settings, from rural areas to major metropolitan cities. CompHealth's specialized recruiters match career preferences, and their experienced support teams handle all details. The position in Saint Cloud, Florida, requires board certification or eligibility, 2+ years of experience, and a preference for head and neck fellowship, but it's not mandatory. Benefits include life insurance, medical benefits, malpractice coverage, retirement plans, CME opportunities, and vacation/holiday time.

No Call, Outpatient Only Geriatrics Job

Company: Curare Physician Recruiting

Location: Saint Petersburg, Florida 33701

Posted Dec 05, 2024

Curare Physician Recruiting is offering a new job for Internal Medicine or Family Medicine physicians near Tampa and Saint Petersburg, FL. The job offers competitive compensation, relocation bonus, and Spanish fluency is required. The company provides customized job search support from writing a standout CV to interview tips and contract negotiation.

Internist for Traditional Practice Opening in Joplin, MO

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Dec 05, 2024

A well-established traditionalist group in Joplin, MO is seeking a BE/BC IM physician for a full-time, hospital-employed position. The role offers a 1:5 call schedule, supportive group of physicians, and a fully established clinic team. The health system provides robust professional support, teaching opportunities, and a financially stable environment. Joplin, known for its vibrant arts scene and historic downtown, offers a unique blend of cultural experiences and small-town charm.

Site Reliability Analyst

Company: Federal Reserve System

Location: St. Louis, MO

Posted Dec 05, 2024

The Federal Reserve Bank of St Louis is looking for a Site Reliability Analyst for their Treasury Debt Management System. The role involves working closely with the FRBNY Production Support team, Treasury Support Division SMEs, and Federal Reserve System SMEs to set up a new operational support model and processes. The Analyst will provide application technical support, troubleshoot complex system issues, and manage request incident change activities. The role requires at least 5 years of relevant experience and an AWS Associate or Professional level certification. The Federal Reserve Bank of St Louis is an Equal Opportunity Employer.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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