Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

RN - Trauma Surgical Nights

Company: Mercy

Location: Saint Louis, Missouri

Posted Dec 05, 2024

This job posting is for an experienced RN or graduate nurse in a 25-bed neurosurgery unit. The position offers a sign-on bonus of $10,000 for experienced RNs and $5,000 for graduates (no contract). Additional incentives include tuition reimbursement, student loan forgiveness, shift differentials, and comprehensive health benefits. The unit specializes in neurosurgery, spinal surgery, and ENT, providing compassionate care to patients with neurological conditions. The nurse-to-patient ratio is 1:5, and the team works closely with physician groups. The job requires a nursing degree, Missouri licensure, and BLS certification. The schedule is 3-12hr shifts (36 hrs/wk) on nights, with weekend and holiday requirements.

Emergency Medicine Physician - Mosaic Life Care, Maryville MO

Company: Mosaic Life Care

Location: Maryville, Missouri

Posted Dec 04, 2024

The Department of Emergency Medicine at Mosaic Life Care in Maryville, MO is recruiting a full-time EM physician. The ideal candidate should be residency trained and board certified/eligible. This position offers a rewarding, challenging experience in a dynamic team. Maryville, MO provides a blend of small-town charm and easy access to Kansas City and Omaha. The facility is a 51-bed acute-care hospital with a high annual ED volume of approximately 8500. Benefits include a competitive salary, bonus, student loan assistance, malpractice insurance, and more.

Licensed Practical Nurse

Company: Wexford Health Sources

Location: East St. Louis, Illinois

Posted Dec 05, 2024

This job posting is for a Licensed Practical Nurse (LPN) position on a PRN basis at Southwestern Illinois Correctional Center in East St. Louis, IL. The LPN, under supervision, will assist in delivering patient care, perform nursing process duties, administer medications, document patient encounters, and maintain a clean and safe environment. The role involves direct interaction with inmates, correctional staff, and healthcare personnel in a correctional facility setting.

Senior Product Manager - Reporting

Company: Gravie

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Gravie is a health benefits company that aims to improve healthcare access through innovative and consumer-centric solutions. They are a fast-growing company with top-tier investors, low revenue churn, and a unique culture that values authenticity, curiosity, creativity, empathy, and outcome orientation. They are looking for a Senior Product Manager to deliver actionable reporting and drive business decision-making.

RN - Obstetrics / L&D (Nights)

Company: Mercy

Location: Aurora, Missouri

Posted Dec 04, 2024

Mercy is offering a Sign On Bonus, PTO Frontload, and Relocation Assistance. The Registered Nurse position involves using the Nursing Process to meet patient needs, ensuring adherence to department and hospital policies. The RN will be responsible for the quality of care of a caseload of patients and may be assigned to work shifts in all four rural hospitals. Mercy provides great benefits including day-one comprehensive health, vision and dental coverage, PTO, tuition reimbursement, and employer-matched retirement funds. The ideal candidate should have compassion, professionalism, a positive outlook, and a strong sense of advocacy.

Reg Respiratory Therapist -Part Time - Mercy Lebanon

Company: Mercy

Location: Lebanon, Missouri

Posted Dec 05, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The role involves direct patient care in respiratory care, consulting physicians, and acting as an advanced resource person. Qualifications include a CoArc approved Respiratory Care program graduation, state licensure, RRT credential, and preferred ACLS and critical care experience. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They promote a supportive community, innovation, and collaboration.

Internal Medicine | Work with St. Louis University Residents in St. Louis, MO

Company: Jackson Physician Search

Location: Missouri

Posted Dec 05, 2024

An established, award-winning Federally Qualified Health Center in St. Louis, MO is seeking a Primary Care Provider. The organization offers a 4-day clinic workweek, NHSC service site with student loan repayment, and an option to teach Family Medicine Residents. St. Louis, a historic metro area with 2.2 million residents, offers world-class attractions, top-ranked schools, and easy access to St. Louis Lambert International Airport.

Radiologic Technologist II - FT, Days - Loan Repay

Company: Mercy

Location: Ozark, Missouri

Posted Dec 05, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer career opportunities tailored to individual skills and talents, with benefits including health coverage, PTO, tuition reimbursement, and retirement funds. Mercy is known for its supportive community and commitment to innovation in healthcare. They provide a Loan Repayment Assistance Program for Imaging co-workers and require qualifications such as a Radiologic Technologist Program graduation, relevant experience, and necessary certifications.

Lead Tester

Company: Radiant Digital

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Radiant Digital offers technology consulting and business solutions for commercial and government clients. They provide end-to-end solution delivery, single project execution, and strategic resources. The company is CMMI Maturity Level III and ISO 9001 2015 certified.

Office Manager

Company: Livefront

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

The text is a job description for an Office Manager position at Livefront. The company values passionate and talented people who work together to make things better. The Office Manager will manage logistics for team retreats, events, and celebrations, capture and organize photo and video content, and support the leadership team. They will also care for the office daily and coordinate with external vendors. The ideal candidate should have a warm personality, be energetic, and have event planning experience. The hiring process is quick and consists of several stages.

Speech Therapist

Company: Mercy

Location: Saint Louis, Missouri

Posted Dec 04, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and heart, having been named one of the 'Top 100 Places to Work' by Modern Healthcare Magazine. The role involves performing assessments, treatment programs, and participating in departmental education. Qualifications include a Master's Degree in Speech/Language Pathology, relevant license, and certification. Benefits are comprehensive, including health coverage, PTO, tuition reimbursement, and retirement funds. Mercy fosters a supportive community, encourages innovation, and values compassion, professionalism, and a positive outlook.

Pharmacy Student

Company: Mercy

Location: Sappington, Missouri

Posted Dec 05, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a top workplace. The role of a Pharmacy Technician involves supporting the Pharmacist in medication preparation, distribution, and inventory control. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and advocates for excellent care.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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