Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

RN Mercy Stoddard Telemetry - PRN

Company: Mercy

Location: Dexter, Missouri

Posted Dec 05, 2024

Mercy Hospital Stoddard is inviting RN Tele nurses to join their team on a PRN basis. They emphasize their commitment to investing in nurses' careers, offering compassionate care, and exceptional service. The hospital values unique skills and talents, and has been recognized by Modern Healthcare Magazine as a 'Top 100 Place to Work'. The role involves utilizing the nursing process, maintaining professional accountability, and coordinating patient care. Qualifications include an accredited nursing degree, current RN license, 1 year of RN experience, and Basic Life Support certification. Mercy encourages applicants who are compassionate, professional, positive, and advocates for excellent care.

Nurse Practitioner Family Medicine opening in MO

Company: Archway Physician Recruitment

Location: Hannibal, Missouri

Posted Dec 05, 2024

Health System in Hannibal, MO is seeking a full-time Nurse Practitioner for Family Medicine. The position offers a 3-year contract with potential renewal, along with a sign-on bonus and educational debt forgiveness. Benefits include comprehensive insurance, malpractice coverage, a pension plan, and an employee child care center. Hannibal, known for its connection to Mark Twain, offers a variety of cultural and recreational activities. Archway Physician Recruitment is facilitating the recruitment process.

Physical Therapist

Company: Mercy

Location: Cape Girardeau, Missouri

Posted Dec 05, 2024

Mercy is a top employer offering comprehensive benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They value compassionate care and professionalism, providing opportunities for growth and innovation. Mercy seeks Physical Therapists with Bachelor, Master, or Doctorate degrees, current licensure, and preferred experience in adult and geriatric care. They emphasize a positive work environment and commitment to excellent care.

Ultrasound Technologist I (Non-Exempt)

Company: Mercy

Location: Cape Girardeau, Missouri

Posted Dec 05, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Places to Work'. The role involves performing ultrasound procedures independently, requiring proficiency in ultrasound equipment and patient handling. Benefits include comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. Mercy seeks individuals with a positive outlook, strong advocacy, and a collaborative spirit.

RN - Med Tele Full Time

Company: Mercy

Location: Springfield, Missouri

Posted Dec 05, 2024

The job posting offers a range of attractive incentives including a sign-on bonus of up to $20,000 for nurses with over a year of experience, education assistance such as loan forgiveness and tuition reimbursement, relocation assistance, and various differentials for night shifts and weekends. The position is full-time, safety-sensitive, and serves a medical cardiac population. Qualifications include a current RN license, BLS certification, and ability to meet physical demands.

RN and LPN Opportunities at Mercy Washington

Company: Mercy

Location: Washington, Missouri

Posted Dec 05, 2024

Mercy Hospital Washington is offering various incentives for nurses, including sign-on bonuses, relocation assistance, education assistance, tuition reimbursement, and competitive salaries. They provide comprehensive benefits such as insurance, retirement funds, and parental leave. Mercy is a faith-based ministry that encourages professional growth and invests in its employees through scholarships, loan reimbursement, and referral bonuses.

Rural Health Nurse Practitioner needed on an Alaskan Island - Strong Comp Package CPH# JOB-3001398

Company: CompHealth

Location: Saint Paul, Alaska

Posted Dec 05, 2024

CompHealth is seeking Nurse Practitioners or Physician Assistants for a rural clinic located on an island off the mainland of Alaska, serving a population under 500 residents. The ideal candidates should have autonomous work experience and be comfortable with the schedule of 8a-5p and shared call duties. The clinic offers a 30% rural health salary differential, including sign-on bonus, relocation assistance, and housing stipend. CompHealth supports applicants throughout the interview process, negotiating compensation and ensuring the best possible offer. The company's services are free for applicants, and they provide specialized recruitment, coordination of interviews, and assistance with licenses.

LPN - Mercy Rehabilitation Hospital St. Louis (Full-time)

Company: Mercy

Location: Chesterfield, Missouri

Posted Dec 05, 2024

Mercy Rehabilitation Hospital St. Louis is offering LPN full-time night shift positions with benefits. The hospital, a state-of-the-art facility, specializes in inpatient rehabilitation services for patients recovering from various conditions. It provides comprehensive, multidisciplinary programs with a focus on improving functional ability and quality of life. The hospital emphasizes a team approach, with experienced Rehabilitation Nurses delivering compassionate care. Qualifications include a high school diploma, LPN license, and certain certifications. Mercy values compassion, professionalism, and a positive outlook, offering opportunities for innovation and growth.

NP/PA Primary Care opening in VT

Company: Archway Physician Recruitment

Location: Saint Johnsbury, Vermont

Posted Dec 05, 2024

A distinguished primary care practice in St. Johnsbury, Vermont, is seeking experienced Nurse Practitioners or Physician Assistants. The position offers competitive compensation and the opportunity to work in a picturesque setting with year-round recreational opportunities. The practice, affiliated with Regional Hospital, holds a Level 3 Patient-Centered Medical Home certification and is a certified Rural Health Clinic. Responsibilities include patient evaluation, treatment, ordering tests, patient management, and collaboration with physicians and other departments.

Outpatient Psychiatrist - Qualifies for Loan Forgiveness + Minimal Call & Supportive Team

Company: SSM Health

Location: Jefferson City, Missouri

Posted Dec 05, 2024

SSM Health St. Mary's Hospital is recruiting a full-time Psychiatrist for their outpatient needs. The position offers an aggressive guaranteed salary, loan support, and qualification for Public Service Loan Forgiveness (PSLF). Benefits include comprehensive benefits, up to 6% retirement contribution, Epic EMR, and a low cost of living in Missouri's capital city. The hospital is located in a state-of-the-art building with a focus on healing environments and patient safety.

Registered Nurse (Non-Exempt) (10013N)

Company: Mercy

Location: Springfield, Missouri

Posted Dec 05, 2024

Mercy is currently recruiting nurses for the Surgical 3B unit, offering competitive incentives such as sign-on bonuses, student loan repayment, and relocation assistance. The unit, with a 1-6 nurse to patient ratio, focuses on pre- and post-surgical patients, particularly GI, Urology, and ENT surgeries. Nurses will gain experience in critical skills like telemetry monitoring, IV insertions, and wound care. Full-time, part-time, and weekend shifts are available, with weekend pay options. Qualifications include a state-approved nursing program graduation, current RN license, and AHA Healthcare Provider certification.

Accounting Internship, Spring 2026

Company: Wipfli

Location: Minneapolis–Saint Paul, MN

Posted Dec 05, 2024

Wipfli offers a career-defining opportunity for interns to gain experience in tax or audit work, prepare individual business and fiduciary tax returns, and work with clients from various industries. The interns will receive hand-on experience, develop skills, and gain exposure to a variety of clients and industries. The company is an equal opportunity employer and provides reasonable accommodations for people with disabilities.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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