Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Pulmonary/Critical Care & Sleep Medicine Physician - Saint Luke's - Kansas City Metro Area

Company: Saint Luke's Health System

Location: Kansas City, Missouri

Posted Nov 25, 2024

Saint Luke's Pulmonary Specialists is recruiting for a BC/BE Pulmonary/Critical Care and Sleep Medicine physician in Lee's Summit, MO. The position involves clinical pulmonary, sleep, and critical care duties in both inpatient and outpatient settings, including telemedicine clinics and sleep study reading time. The practice is part of Saint Luke's East Hospital, which has a robust pulmonary and critical care department, an interventional bronchoscopy program, and a busy sleep department. The team has close working relationships with various specialties and is affiliated with UMKC Medical School for teaching opportunities. Saint Luke's offers a competitive employment package with a guaranteed salary, excellent benefits, and opportunities for CME.

Maternal Fetal Medicine Physician - Saint Luke's - Kansas City, MO

Company: Saint Luke's Health System

Location: Kansas City, Missouri

Posted Nov 25, 2024

Saint Luke’s Hospital of Kansas City is recruiting for a maternal-fetal medicine position. The role involves 4 clinical days and 1 admin day weekly, with an integrated laborist program ensuring a good work-life balance. The position includes an adjunct professorship at the University of Missouri–Kansas City School of Medicine, opportunities for leadership, and a competitive employment package. The hospital, named a top maternity care center, features a Level III NICU and offers a range of inpatient, outpatient, and telemedicine services. Saint Luke’s Health System, a faith-based, not-for-profit health system, is committed to providing high-quality care across Missouri and Kansas.

Physical Therapist

Company: Mercy

Location: St. Louis, Missouri

Posted Nov 25, 2024

Mercy Health Center is seeking a Physical Therapist with a Bachelor, Master, or Doctorate degree in Physical Therapy, and a current Missouri license. The role involves performing assessments and treatment programs for adult and geriatric patients under the supervision of a Rehab Therapy supervisor. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, a positive outlook, and advocacy, with opportunities for innovation and career growth.

Manager, Digital Marketing Analytics

Company: Ameriprise Financial Services, LLC

Location: Minneapolis–Saint Paul, MN

Posted Nov 25, 2024

Ameriprise Financial is seeking a Manager of Digital Marketing Analytics to join their team. The role involves leading a group of analysts, providing actionable insights, and driving tangible business results. The company offers a competitive salary and comprehensive benefits program.

RN - Medical Stepdown - Nights

Company: Mercy

Location: Sappington, Missouri

Posted Nov 25, 2024

Mercy South Medical Stepdown is seeking experienced and graduate nurses. They offer a residency program, sign-on bonuses, and no contracts. The unit specializes in acutely ill medical patients, requiring strong critical thinking and decision-making skills. The RN ratio is 3-4 patients with tech support, and there's 24/7 leadership support. Benefits include comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. Mercy values compassion, professionalism, and a positive outlook.

A Missouri Facility Seeks a Locums Critical Care Medicine Physician CPH# JOB-3000840

Company: CompHealth

Location: Joplin, Missouri

Posted Nov 25, 2024

CompHealth, a reputable healthcare staffing company founded in 1979, offers locums assignments in Pulmonary Critical Care in Joplin, Missouri. With a vast network of connections, they can help find the perfect assignment, negotiate better pay, arrange housing and travel, and simplify the credentialing process. Their specialized recruiters provide comprehensive support, ensuring a smooth experience for healthcare providers.

A Facility in MO Seeks a Locums Urologist WBY# JOB-3000363

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 25, 2024

Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for various medical professionals. They offer a Urology position in Missouri with competitive compensation, paid malpractice insurance, and pre-paid travel and housing expenses. Benefits also include 24-hour access to a consultant and membership in NALTO. The company aims to address healthcare challenges like physician burnout and staffing shortages.

A Facility in MO Needs a Locums Pulmonologist WBY# JOB-3000726

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 25, 2024

Weatherby Healthcare, a leading locum tenens staffing company, is offering a Pulmonary Critical Care position in Missouri. The role requires active state license, BC or BE, ACLS, and various inpatient procedures experience. Benefits include competitive compensation, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, specializes in addressing healthcare staffing challenges.

Aug - Dec 2024- New Graduate Nurse Residency - Mercy Washington

Company: Mercy

Location: Washington, Missouri

Posted Nov 25, 2024

Mercy Washington's Graduate Nurse Residency is currently accepting applications. New graduates are welcome to apply and can benefit from a Sign-On Bonus up to $10,000, Stay Premium Program, Education Assistance, and up to $20,000 Loan Forgiveness. Other incentives include Tuition Reimbursement, comprehensive medical, dental & vision insurance, PTO/Vacation Time, and Employer-Matched Retirement Funds. The residency offers opportunities in various departments such as Cardiac Telemetry, Emergency Department, ICU, Medical Surgical, Women Services.

Ultrasound Technologist, PRN - Joplin

Company: Mercy

Location: Joplin, Missouri

Posted Nov 25, 2024

Mercy is a top employer offering comprehensive benefits, including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They value compassionate care and exceptional service, seeking individuals with a positive outlook and strong advocacy. The role involves interpreting orders, producing diagnostic ultrasound images, and assisting physicians in interventional procedures. Candidates must have a minimum of Registered Diagnostic Medical Sonography with registry in at least one advanced modality or satisfactory completion of formal Radiologic Technology training.

Individual Tax Assistant

Company: TIAA

Location: St. Louis, MO

Posted Nov 25, 2024

The job posting is for a Tax Accountant I role at TIAA, responsible for financial reporting, tax data analysis, and filing. The role requires a university degree and no experience is required. The job offers a base pay range of $2043-$2966 per hour.

Sr Software Engineer (Java/Kotlin)

Company: DataSite

Location: Minneapolis–Saint Paul, MN

Posted Nov 25, 2024

Datasite is building a new platform to provide powerful and innovative solutions to enable clients to manage complex deals. They are looking for a Senior Back End Engineer to join the distributed team.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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