Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

A MO Facility Needs a Locum Tenens Hospitalist WBY# JOB-3000934

Company: Weatherby Healthcare

Location: West Plains, Missouri

Posted Nov 25, 2024

Weatherby Healthcare, founded in 1995, is a leading locum tenens staffing company for physicians, PAs, and NPs. They offer a Hospitalist position in West Plains, Missouri with competitive compensation, paid malpractice insurance, and pre-paid travel/housing. The role requires an active state license, BC or BE, and participation in 12-hour night shifts. Credentialing and DEA registration are necessary. Benefits include 24-hour consultant access and NALTO membership.

An Obstetrics/Gynecologist Is Needed for Locum Tenens Help in Missouri WBY# JOB-3001203

Company: Weatherby Healthcare

Location: Osage Beach, Missouri

Posted Nov 25, 2024

Weatherby Healthcare offers a supportive locum tenens lifestyle for OB/GYN specialists in Osage Beach, Missouri. The assignment includes seeing 20-25 patients daily, full scope of office and call coverage, and competitive compensation. Benefits include paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

A Missouri Facility Is Searching for a Locums Emergency Medicine Physician CPH# JOB-3000529

Company: CompHealth

Location: Branson, Missouri

Posted Nov 25, 2024

CompHealth, a reputable healthcare staffing company founded in 1979, offers a vast network of connections to facilities nationwide. They specialize in finding the perfect locums assignment for Emergency Medicine specialists, like the one in Branson, Missouri. Their services include negotiating better pay, arranging housing and travel, providing malpractice coverage, and simplifying the credentialing process. A dedicated recruiter handles every detail, ensuring a seamless experience.

OB/GYN Physician Opportunity in Southwest Missouri CPH# JOB-2998512

Company: CompHealth

Location: Joplin, Missouri

Posted Nov 25, 2024

CompHealth is offering an OB/GYN position in Joplin, Missouri, a city surrounded by lakes and rivers with numerous outdoor activities. The town is close-knit and friendly, with easy access to universities and major cities. CompHealth will provide support throughout the recruitment process, including salary negotiation, license coordination, and interview scheduling. The position offers benefits such as 4 weeks of vacation, loan repayment, and use of da Vinci robots. Epic EMR is used, and there's a strong mix of OB/GYN services.

Reg Respiratory Therapist (Non-Exempt)

Company: Mercy

Location: Joplin, Missouri

Posted Nov 25, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The role involves direct patient care in respiratory care, consulting physicians, and acting as an advanced resource person. Qualifications include a CoArc approved Respiratory Care program graduation, state licensure, RRT credential, and preferred ACLS and critical care experience. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They promote a supportive community, innovation, and growth, seeking candidates with compassion, professionalism, positive outlook, and advocacy.

RN - OR PACU Rolla (Days)

Company: Mercy

Location: Lebanon, Missouri

Posted Nov 25, 2024

Mercy is offering a Registered Nurse position with attractive benefits including a sign-on bonus, PTO frontload, and relocation assistance. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating care with other departments. Qualifications include being a graduate of an accredited nursing program, having a current RN license, and possessing various certifications. Mercy values compassion, professionalism, and a positive outlook, offering a supportive community and opportunities for innovation in healthcare.

Hematologist Oncologist Needed in St. Louis, Missouri; Lucrative Earning Potential CPH# JOB-3000554

Company: CompHealth

Location: St. Louis, Missouri

Posted Nov 25, 2024

The greater St. Louis area is a vibrant cultural hub with diverse industries, attractions, and educational opportunities. CompHealth, a leading healthcare staffing company since 1979, offers a Hematology Oncology position with a group of 6 physicians, sign-on bonus, relocation assistance, strong earning potential, and leadership opportunities. The location provides easy access to amenities and CompHealth's services are free for candidates, including salary negotiation, interview coordination, and license assistance.

LPN GIG- Flex/Per Diem/PRN - $30/hr base + incentives - Mercy Springfield

Company: Mercy

Location: Springfield, Missouri

Posted Nov 25, 2024

Mercy Springfield Hospital is offering a flexible per diem/flex LPN position with incentives. The base rate is $30/hr, with variable shift incentives available. The schedule is flexible, allowing nurses to choose day or night shifts without weekend, holiday, or shift requirements. The Gig Nursing Program requires scheduling a minimum number of hours, being available on short notice, and flexibility for last-minute cancellations. Qualifications include a valid Missouri LPN license, one year of recent inpatient LPN experience, BLS certification, and IV certification for LPNs working in Missouri. The position is safety-sensitive, requiring constant alertness and safe work practices.

An Interventional Cardiologist Is Needed for Locums Coverage in MO CPH# JOB-3000734

Company: CompHealth

Location: Missouri

Posted Nov 25, 2024

CompHealth, a leading healthcare staffing company since 1979, offers specialized recruiters for Interventional Cardiology locum tenens positions in Missouri. They provide comprehensive support including housing, travel arrangements, credentialing, licensing, and negotiating better pay. The role involves weekdays, call, weekend call, and managing an average of 15 patients per day. Required qualifications include active state license, BC, DEA, and skills in STEMI call coverage, angioplasty, stent placement, caths, IABP, and atherectomy.

New Graduate Nurse - RN Spring/Summer 2025 Grads - Mercy Joplin

Company: Mercy

Location: Joplin, Missouri

Posted Nov 25, 2024

Mercy Joplin is offering a Graduate Nurse position with multiple departments open for new graduates, including Ortho/Neuro, Med Surg, Surgical Cardiac, Renal/Oncology, and Behavioral Health. The position offers a $10,000 sign-on bonus, Mercy Stay Premium Pay Program, up to $600 voucher for NCLEX review, Mercy Apparel voucher, and up to $20,000 RN Loan Forgiveness program. Other benefits include day-one comprehensive health, vision, and dental coverage, PTO, tuition reimbursement, and employer-matched retirement funds. Mercy values compassion, professionalism, positive outlook, and strong advocacy. The role is safety-sensitive.

Emergency Medicine Physician Is Needed for Locums Help in Missouri WBY# JOB-3000510

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 25, 2024

Weatherby Healthcare, founded in 1995, is a leading locum tenens staffing company for physicians, PAs, and NPs. They offer an Emergency Medicine position in Missouri with competitive compensation, paid malpractice insurance, and pre-paid travel/housing. The role involves 12-hour to 24-hour shifts, handling 45 patients per 24 hours, and requires active state license, specific certifications, and DEA. Consultants are available 24/7 for support.

Locums Obstetrics/Gynecologist Is Wanted in MO CPH# JOB-3001160

Company: CompHealth

Location: Missouri

Posted Nov 25, 2024

CompHealth offers comprehensive locums support for OB/GYN professionals in Missouri. They handle credentialing, housing, travel arrangements, and negotiate better pay. The role involves managing standard clinic OB and GYN patients, with 22-25 patients per day in clinic and 650-700 deliveries per year. CompHealth simplifies the credentialing process and provides malpractice coverage.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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