Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Academic Vascular Surgeon - St. Louis, MO

Company: SSM Health

Location: Saint Louis, Missouri

Posted Nov 24, 2024

SSM Health Saint Louis University Hospital is seeking a vascular and endovascular surgeon to join their full-time faculty. The division covers multiple hospitals and the John Cochran VA Medical Center, offering operating responsibilities at a minimum of 2 facilities. The position includes teaching responsibilities and opportunities for research. SSM Health provides a comprehensive benefits package, including medical, dental, vision, and retirement plans. Saint Louis University Hospital, a Level 1 Trauma Center, offers advanced healthcare solutions and is the medical teaching hospital for Saint Louis University School of Medicine. St. Louis is a livable city with an affordable housing market, trendy neighborhoods, and a booming economy.

Physician - Infectious Disease - Full Time - Jefferson City, MO

Company: SSM Health

Location: Jefferson City, Missouri

Posted Nov 24, 2024

SSM Health St. Mary's Hospital in Jefferson City, MO is recruiting for a full-time infectious disease physician. The role offers a blend of inpatient and outpatient services, excellent support staff, and competitive compensation. The hospital, located in Missouri's state capital, is a full-service facility with advanced medical services. It features an evidence-based design focusing on healing environments and patient safety. The position includes no call, onsite clinic hours from Monday to Friday, 8 a.m.–5 p.m., and ICU runs at night with an onsite hospitalist team. The hospital is committed to equal employment opportunity and offers excellent benefits.

Subrogation Negotiator

Company: Element Fleet Management

Location: Minneapolis–Saint Paul, MN

Posted Nov 24, 2024

Element Fleet Management is looking for a Subrogation Negotiator to join their team. The role involves negotiating settlements and resolutions of auto property damage claims. The company offers a culture of innovation, empowerment, and accountability, as well as comprehensive health and welfare benefits.

Physician - Glaucoma Specialist - SLUCare Physician Group

Company: SSM Health

Location: St. Louis, Missouri

Posted Nov 24, 2024

SSM Health is seeking a full-time fellowship trained glaucoma specialist for its expanding department at SLUCare Physician Group. The role involves clinical practice, education of residents, fellows, and medical students, research collaboration, and call coverage at SSM Health Saint Louis University Hospital. The hospital is a 365-bed tertiary-care center, serving a wide radius around St. Louis. The position offers strong compensation, sign-on bonus, student loan repayment, CME allowance, and comprehensive benefits. St. Louis is described as a livable city with affordable housing, trendy neighborhoods, and a booming economy.

Physician - Gastroenterologist

Company: SSM Health

Location: Jefferson City, Missouri

Posted Nov 24, 2024

SSM Health St. Mary's Hospital in Jefferson City, Missouri, is recruiting a full-time Gastroenterologist Physician. The role involves both inpatient and outpatient care, with a schedule of Monday-Friday, 8:00AM-5:00PM. The hospital offers an excellent onboarding process, a two-year guarantee salary with productivity-based bonuses, and comprehensive benefits. It's part of a fully integrated system using Epic EMR for improved care coordination. The hospital, located in Missouri's state capital, has a rich history and offers top-tier benefits. It serves patients needing various services, including emergency, cardiology, orthopedic, cancer, maternity, and medical imaging. The hospital emphasizes privacy, safety, efficiency, access, and healing. The location provides a mix of urban and natural attractions, with vibrant communities and opportunities for outdoor activities.

RN Opportunities- Mercy Hospital Lincoln

Company: Mercy

Location: Troy, Missouri

Posted Nov 24, 2024

Mercy Hospital Lincoln is offering various incentives for nurses, including sign-on bonuses, education assistance, loan forgiveness, comprehensive benefits, and competitive salaries. They also provide shift differentials, PTO, retirement funds, parental leave, and tuition reimbursement. Qualifications include a degree from an accredited nursing program, current RN license, and BLS certification.

Physician OB/GYN

Company: Community Health Systems

Location: Poplar Bluff, Missouri

Posted Nov 24, 2024

Poplar Bluff Regional Medical Center is recruiting an additional Board Certified/Board Eligible OB/GYN for an employed position. The facility is new, state-of-the-art, and offers a competitive recruitment package including a MGMA competitive salary, full employee benefits, commencement bonus, student loan repayment assistance, and more. The community is clean, safe, family-friendly with a low cost of living, and offers access to outdoor activities and a strong public school system.

LPN - Outpatient Services (PRN Days)

Company: Mercy

Location: Cassville, Missouri

Posted Nov 24, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, having been named one of 'Top 100 Places to Work' by Modern Healthcare Magazine. The LPN role involves providing patient care under supervision, maintaining patient rights, and adhering to Mercy's mission and standards. Essential qualifications include LPN licensure, physical demand capabilities, and relevant certifications. Mercy provides comprehensive benefits and fosters a supportive community focused on pioneering care models and utilizing advanced technology.

Neurosurgery Physician

Company: HCA Healthcare

Location: Independence, Missouri

Posted Nov 24, 2024

Centerpoint Medical Center is recruiting a board certified or board eligible neurosurgeon for a premier practice in Kansas City Metro. The role offers a 75/25 spine and cranial mix, immediate ramp availability, and opportunities for career growth. The medical center boasts advanced technology, a strong complement of subspecialists, and a patient-first culture. It features a Level II Trauma Center, accredited chest pain center, orthopedic services, stroke center, and women's services. The Kansas City region offers a high quality of life with numerous corporate headquarters, excellent travel connectivity, and a vibrant food scene. Kansas City ranked No. 19 on Forbes' list of the 20 Happiest Cities to Work in Right Now.

OBGYN Opportunities with CoxHealth in Springfield, Missouri

Company: CoxHealth Provider Recruitment

Location: Southwest Missouri

Posted Nov 24, 2024

CoxHealth offers OBGYN positions in their reputable Springfield, Missouri practices. Key features include a 4-day workweek, favorable call schedule, and a supportive team. Benefits comprise competitive salary, sign-on bonus, CME allowance, and malpractice insurance. Springfield boasts a low cost-of-living, excellent schools, and abundant outdoor activities. CoxHealth, a physician-led, not-for-profit system since 1906, is recognized as a Best Place to Work.

Polysomnographic Tech - PRN, Nights - Mountain View

Company: Mercy

Location: Mountain View, Missouri

Posted Nov 24, 2024

Mercy Hospital St. Francis in Mountain View, MO is seeking a Registered Polysomnographic Technologist. The role involves performing and processing sleep studies on adult and pediatric patients, requiring a high school diploma or equivalent, and at least one year of sleep lab experience. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The hospital emphasizes compassionate care, professionalism, and a positive outlook, with opportunities for career growth and innovation in healthcare.

Manager, Order Entry & Resolution

Company: Element Fleet Management

Location: Minneapolis–Saint Paul, MN

Posted Nov 24, 2024

Element Fleet Management is looking for a Manager Order Entry and Resolution to join their team. The company is committed to delivering a superior client experience and fostering a culture where every employee can make a difference. The role requires strong leadership, knowledge of the fleet industry, and strategic planning skills.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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