Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

RN - Labor and Delivery, Regional Float Pool- Nights

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 22, 2024

Mercy offers a range of incentives for nurses, including a sign-on bonus up to $10,000, education assistance, and tuition reimbursement. They provide comprehensive benefits like medical, dental, and vision insurance, PTO, and retirement funds. The Float Pool offers opportunities for clinical skill development and teamwork across various locations. A Regional Travel RN position is also available for experienced Labor and Delivery RNs.

Software Engineering Senior Advisor

Company: Cigna

Location: St. Louis, MO

Posted Nov 22, 2024

The job description is for a Software Engineering Senior Advisor role at Cigna Group, requiring expertise in software engineering, data analysis, and Pega technology. The candidate will work on delivering business needs, implementing transformational solutions, and providing technical solutions to a wide range of difficult problems.

Intensivist Nocturnist - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Nov 22, 2024

Mosaic Life Care, a physician-led healthcare system, is seeking a BC/BE Intensivist Nocturnist for part-time work at their St. Joseph, Mo campus. The role offers a challenging and engaging experience in a growing intensivist program. The organization focuses on improving quality, patient satisfaction, and ICU performance. The practice details include a cooperative atmosphere, flexible scheduling, 12-hour shifts from 6 pm to 6 am, and an opportunity to work with a collegial group of 7 physicians. Mosaic Life Care provides a competitive salary, bonus opportunity, student loan assistance, comprehensive insurance, CME reimbursement, and numerous other benefits.

Heart Failure/ Shock Cardiologist for an Academic Cardiology Practice in the Saint Louis Metropolitan Area

Company: SSM Health

Location: Saint Louis, Missouri

Posted Nov 22, 2024

SSM Health is seeking a Heart Failure Cardiologist to lead inpatient management of cardiogenic shock and advanced heart failure at SSM Health-Saint Louis University Hospital. The role involves developing shock management protocols, establishing a referral network, and potentially becoming a Medical Director. Preference is given to candidates with subspecialty fellowship training. The position offers flexible scheduling, excellent work-life balance, competitive salary, and opportunities for teaching and research. St. Louis, the city where the hospital is located, is known for its affordable housing, trendy neighborhoods, and vibrant cultural scene.

Physician- Neurosurgery - Full Time Academic - SLUCare Physician Group

Company: SSM Health

Location: St. Louis, Missouri

Posted Nov 22, 2024

SSM Health is recruiting a neurosurgeon for a split opportunity between a community hospital and a large academic center. The position requires spine fellowship or equivalent experience and offers participation in resident education, clinical research, and access to advanced medical technology. The community hospital is a 144-bed non-trauma center, part of a 14-hospital health system. The academic center is a level I teaching hospital with comprehensive stroke designation. St. Louis, where the hospitals are located, is described as a livable city with an affordable housing market, trendy neighborhoods, and a booming economy.

Radiologic Technologist PRN Perry

Company: Mercy

Location: Perryville, Missouri

Posted Nov 22, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy is looking for Radiologic Technologists with ARRT registry or registry eligibility, who can perform radiographic procedures independently. The role involves technical skills, understanding of anatomy, and ability to handle stressful situations. Mercy promotes a supportive community, innovation, and professional growth.

LPN - Regional Float Pool (Full Time and Part Time)

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 22, 2024

Mercy Regional offers a Float Pool for experienced nurses with a sign-on bonus up to $2,000, tuition reimbursement, comprehensive insurance, and increased weekend differential. The Float Pool provides opportunities to develop clinical skills, sharpen communication, and work in various units. Qualifications include 1-2 years bedside experience, a nursing degree, current LPN license, and BLS certification. Mercy also offers a Regional Travel LPN position for experienced LPNs.

Staff AI Implementation Engineer

Company: ServiceNow

Location: St. Louis, MO

Posted Nov 22, 2024

The job description is for an AI Solution Success team member within the Platform Product organization at ServiceNow. The role involves implementing AI products on the Now platform for early adopter customers, learning and supporting customers with existing AI products, and debugging and finding quick workarounds for issues. The ideal candidate has technical skills in ServiceNow Workflows and Flow Designer, expertise in scripting Glide JavaScript, and experience handling integrations with various systems and building applications on the platform.

Administrative Coordinator

Company: Norton Rose Fulbright

Location: St. Louis, MO

Posted Nov 22, 2024

The job description is for an Administrative Coordinator position in the St Louis office of Norton Rose Fulbright US LLP. The role requires a dependable and polished individual to provide high-level customer service and support to the office. The job involves coordinating logistics, assisting with office budget preparation, and processing expenses. The firm offers a comprehensive benefits package, including access to three medical plans, dental, vision, and life insurance, as well as a 401k savings plan and profit-sharing plans.

Phlebotomist - PRN

Company: Mercy

Location: Saint Louis, Missouri

Posted Nov 22, 2024

Mercy is seeking a Laboratory Support Technician (LST II) to join their provider care team. The role involves supporting reports, data, and scheduling functions in the laboratory, ensuring accurate, timely, and effective service. The ideal candidate will have phlebotomy or clinical laboratory experience, and adhere to Mercy's service standards and HIPAA requirements. Mercy offers comprehensive benefits and encourages a collaborative, compassionate work environment focused on innovation and excellent care.

Manager, Program Management

Company: EVERSANA

Location: St. Louis, MO

Posted Nov 22, 2024

The job description is for a Manager Program Management position at EVERSANA, a company that is committed to improving patient lives. The role involves overseeing a team, managing activities, and developing policies. The company values diversity, equity, and inclusion, and offers competitive salaries and benefits.

LPN - Ortho Neuro Full Time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Nov 22, 2024

The job posting offers a sign-on bonus ranging from $2,000 to $10,000 based on years of experience, education assistance, tuition reimbursement, relocation assistance, and various differentials. The position is in a Surgical Unit focusing on adult post-operative orthopedic traumas and Neurosurgery, providing opportunities for developing critical thinking and clinical skills.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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