Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent as the city blends a strong manufacturing legacy with a growing fintech and healthcare IT scene. With 3,579 open tech roles, companies from HCA Healthcare to startup incubators in Midtown and The Block are actively hiring. The city’s business-friendly tax incentives and proximity to the Midwest’s largest transportation hub give tech professionals access to high-paying roles without the high cost of tech-centric coasts.

The region’s tech ecosystem spans healthcare IT, logistics software, fintech, and manufacturing automation. Centene’s data‑science teams, HCA’s cybersecurity engineers, and logistics giants like UPS and FedEx use local talent to power telehealth platforms and supply‑chain analytics. Startups such as Raptor Labs in the Delmar Loop and Kingfisher Labs in Forest Park focus on AI and blockchain, creating a diverse portfolio of opportunities for software engineers, product managers, and DevOps specialists.

Saint Louis offers a moderate cost of living—average rent in Tower Grove or Forest Park is around $1,200–$1,600 per month, and groceries and utilities stay below national averages. Transparent salary information lets candidates evaluate whether a $100,000 software engineering role aligns with their living expenses, especially when considering benefits, relocation packages, and the city’s robust public transportation network.

Operations Support Specialist (Onsite)

Company: One80 Intermediaries

Location: Minneapolis–Saint Paul, MN

Posted Nov 22, 2024

The Operations Support Specialist role at One80 Intermediaries involves handling insurance documents, troubleshooting office machines, and maintaining security and confidentiality. The company offers a comprehensive compensation package and is an equal opportunity workplace.

Events Specialist

Company: M3USA

Location: St. Louis, MO

Posted Nov 22, 2024

M3 USA is a company that offers digital solutions in healthcare, life sciences, and pharmaceuticals. They are hiring for an Events Specialist position to support the Marketing department in organizing and planning trade shows and conferences.

Consulting Architect

Company: Mirantis

Location: St. Louis, MO

Posted Nov 22, 2024

Mirantis is a company that helps organizations achieve digital self-determination by providing complete control over their strategic infrastructure. They offer a range of products and services, including cloud-native expertise, intelligent automation, and open-source solutions. The company is looking for a Consulting Architect to join their team, who will work with clients to define a vision and lead them to strategic solutions.

TRSO Associate Consultant

Company: Federal Reserve System

Location: St. Louis, MO

Posted Nov 22, 2024

The Federal Reserve Bank of St Louis is seeking a TRSO Associate Consultant to provide project management oversight, website maintenance, and communication support for Treasury Support business lines and administrative support. The role will report directly to a Senior Manager and will provide opportunities to influence, facilitate executive communications, and work with executive leadership to help improve processes.

Physician - Pediatric Hospitalist - Jefferson City, MO.

Company: SSM Health

Location: Jefferson City, Missouri

Posted Nov 22, 2024

SSM Health St. Mary's Hospital in Jefferson City, MO, is seeking a Pediatric Hospitalist Physician to join their established pediatric team. The hospital, a full-service, community hospital with a rich history, offers a 7 On / 7 Off Schedule, seasoned support staff, and comprehensive benefits including a Sign On Bonus, Loan Repayment, Retirement Savings Options, and $5,000 Yearly CME Reimbursement. The hospital is located in Missouri's state capital, offering a vibrant community with access to nature at the Lake of the Ozarks. SSM Health is committed to equal employment opportunity.

Admin Support Specialist

Company: Centrex Rehab

Location: Minneapolis–Saint Paul, MN

Posted Nov 22, 2024

Centrex Rehab is looking for an Admin Support Specialist for its corporate office team in Bloomington, MN. The role is a full-time position with benefits eligibility, requiring a collaborative team player with great attention to detail.

Product Management Intern

Company: IDeaS

Location: Minneapolis–Saint Paul, MN

Posted Nov 22, 2024

IDeaS is a global powerhouse of innovation and excellence, offering a internship program for students to gain real-world experience and build successful careers. The company values diversity, inclusivity, and employee growth, and is an equal opportunity employer.

Family Medicine Physician - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Nov 22, 2024

Mosaic Life Care, a physician-led healthcare system, is seeking a BC/BE Family Medicine physician for a rewarding career in St. Joseph, MO. The position offers work-life balance, access to modern tools, competitive salary, benefits, and professional security. The practice is collaborative, involving one additional physician, three APPs, and a supportive team. It includes outpatient work, clinic call coverage, and no ER or OB duties. Mosaic Life Care provides a range of benefits including a starting bonus, student loan assistance, comprehensive insurance, CME reimbursement, and more.

Occupational Therapist -Full Time-Mercy Aurora

Company: Mercy

Location: Aurora, Missouri

Posted Nov 22, 2024

Mercy is a healthcare organization that offers compassionate care and exceptional service. They believe in careers that match unique individuals' gifts, skills, and talents. The company provides great benefits, including comprehensive health coverage, tuition reimbursement, and employer-matched retirement funds. They encourage applicants who share their values of compassion, professionalism, and advocacy.

LPN - Psych Full Time Days

Company: Mercy

Location: Springfield, Missouri

Posted Nov 22, 2024

The job posting offers a range of incentives including sign-on bonuses, relocation assistance, education assistance, and comprehensive insurance. The patient population consists of individuals with various mental health conditions requiring 24-hour intervention. The role involves psychiatric assessment, medication management, therapy, and community resource connections. Qualifications include an accredited practical nursing program graduation, LPN license, and certain certifications. Physical demands include lifting 50 pounds, prolonged standing, and various movements.

Emergency Medicine Physician Assistant

Company: HCA Healthcare

Location: Kansas City, Missouri

Posted Nov 22, 2024

Centerpoint Medical Center in Kansas City, Missouri, is recruiting a full-time, board-certified Physician Assistant with at least one year of Emergency Medicine experience and NIHSS certification. The center offers competitive compensation, robust benefits, professional development opportunities, and advanced training. Centerpoint boasts state-of-the-art facilities, a wide range of specialties, and is located in a thriving region with excellent travel connections and a high quality of life.

Sr Cloud Engineer

Company: Federal Reserve System

Location: St. Louis, MO

Posted Nov 22, 2024

The Federal Reserve Bank of St Louis is seeking an expert AWS Cloud Engineer with additional skills in Oracle and Java development. The job offers a competitive salary, comprehensive benefits package, and opportunities for growth and development.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis hosts a wide spectrum of tech roles, from software engineers (full‑stack, mobile, backend) and data scientists at Centene to cybersecurity analysts at HCA Healthcare. Product managers, UX designers, and DevOps specialists are in demand at logistics firms like UPS and FedEx, while AI/ML engineers find opportunities at startups such as Raptor Labs and Kingfisher Labs.
Are tech roles in Saint Louis remote, hybrid, or on‑site?
Most senior positions at large employers like HCA and Centene offer hybrid options, allowing employees to work from the downtown office two days a week and remotely the rest. Startups in Midtown and The Block typically require on‑site presence to foster collaboration, but many are expanding their remote talent pool due to the pandemic‑shifted culture.
Who are the major tech employers in Saint Louis?
Key employers include HCA Healthcare’s digital health division, Centene’s analytics teams, UPS and FedEx’s logistics tech hubs, Boeing’s aerospace software labs, and local innovators such as Raptor Labs, Kingfisher Labs, and Innovate St. Louis. The city also attracts national firms like Google and Microsoft through satellite offices.
What salary can I expect for tech roles in Saint Louis?
Software engineers earn between $80,000 and $110,000, with senior positions reaching $120,000+. Data scientists typically earn $90,000–$130,000, while cybersecurity experts command $95,000–$140,000. Benefits packages often include health insurance, retirement plans, and relocation stipends, which can significantly increase total compensation.
How can I relocate to Saint Louis for a tech job?
Start by researching neighborhoods: Tower Grove offers a vibrant student vibe, Delmar Loop offers boutique shopping, and Forest Park provides suburban tranquility. Many employers provide relocation assistance, including housing stipends and moving allowances. Utilize the city’s public transit (MetroLink) and bike lanes to stay connected once you arrive.

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