Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Physician Assistant (PA) Cardiology

Company: Community Health Systems

Location: Moberly, Missouri

Posted Nov 08, 2024

Merit Health River Oaks, a 155-bed full-service hospital, is seeking a Cardiology Physician Assistant. The role involves assisting a Cardiologist in an outpatient practice, with no in-hospital call duties. The hospital is offering a comprehensive recruitment package including a competitive salary, commencement bonus, and additional benefits like marketing, relocation, and CME. Flowood, a suburb of Jackson, Mississippi, with a population of 4,500, is known for its strong school system, excellent recreational facilities, beautiful parks, and year-round events, offering a relaxed and family-friendly lifestyle.

Outpatient Neurologist - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Nov 08, 2024

Mosaic Life Care's Neurology Department is recruiting a BE/BC Neurologist for an outpatient clinic. The position offers a flexible schedule with no weekend or call coverage, and opportunities to perform Botox injections, EMG, and EEG interpretation. The community of St. Joseph provides a family-friendly atmosphere with excellent schools, parks, restaurants, and community activities. Mosaic Life Care, a member of the Mayo Clinic Network, offers a highly competitive salary, student loan assistance, comprehensive insurance, ample time off, CME reimbursement, a 401(k) plan, and relocation assistance.

RN - Pediatrics / Full Time, Shift Nights

Company: Mercy

Location: Joplin, Missouri

Posted Nov 08, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and hearts, and have been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating care with other departments. Qualifications include a nursing degree, current RN license, and various certifications. Preferred experience includes 1 year in a pediatric unit. Mercy offers great benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They promote a supportive community, innovation, and excellent care.

Physician – OBGYN – Mercy Southeast in Cape Girardeau, MO

Company: Mercy Clinic

Location: Cape Girardeau, Missouri

Posted Nov 08, 2024

Mercy OBGYN is seeking board certified or eligible physicians to join their busy practice in Cape Girardeau, MO. The team consists of three physicians, two midwives, and two advanced practitioners. The new clinic features a full Women's Integrated Health program with onsite Breast Health Services, diagnostic testing, and pelvic floor physical therapy. Benefits include a competitive income guarantee, flexible recruitment incentives, comprehensive benefits, and a supportive work-life balance. Cape Girardeau offers a family-friendly vibe with endless activities, a lively downtown, and excellent educational and recreational facilities.

Spanish Toponymist- TS/SCI with Poly REQUIRED

Company: Leidos

Location: St. Louis, MO

Posted Nov 08, 2024

Leidos is looking for a Spanish Toponymist-Journeyman (Geospatial Linguist) to support a customer site. The role involves analyzing and conflating information from the Geographic Names Database (GNDB), using Geographic Names Processing Systems (GNPS), charts, imagery, and geospatial tools. The candidate will also prepare files and maps, accurately enter data to maintain and update the GNDB, and respond to use questions via the Ad Hoc Query process. The ideal candidate should have a BA degree or Master's with relevant experience, ILR Skill Level Two certification for reading in Spanish, and experience with ArcGIS or GeoMedia Pro. Active TS/SCI clearance is required, and the candidate should be willing to obtain a POLY level clearance. The role involves scanning and geo-referencing hardcopy maps, researching and ordering geospatial data sources, and interpreting policies from the US Board on Geographic Names, Department of State, and NATO.

Account Manager Omnicare - Minneapolis, MN

Company: CVS Health

Location: Saint Paul, MN

Posted Nov 08, 2024

CVS Health is seeking an Account Manager for Omnicare, a role that involves managing local client relationships, developing and retaining business, and ensuring customer satisfaction. The ideal candidate will have 2+ years of customer-facing experience, CRM proficiency, and strong business acumen. They will build trust with clients, manage routine client support activities, and collaborate with internal teams to address customer risks and opportunities. The role offers a competitive pay range, comprehensive benefits, and opportunities for professional growth within a company committed to improving health care.

Solar Appointment Setter

Company: Sunrun

Location: Missouri City, TX

Posted Nov 08, 2024

Sunrun, a leading U.S. solar, storage, and energy services company, is hiring for a retail position. The role involves acting as the face of Sunrun in a designated partner retail store, building relationships, and educating potential customers on renewable energy and storage solutions. The successful candidate will have strong communication skills, technology skills, resilience, self-motivation, and passion for the mission. Sunrun offers a full benefits package, competitive sales commissions, and opportunities for career advancement. The top performers can earn up to $160,000/year.

Business Development Associate

Company: Square

Location: St. Louis, MO

Posted Nov 08, 2024

Square is looking for high-energy motivated professionals to help build their Sales Development organization. The company is expanding its omnichannel solutions to help sellers grow their businesses and compete at a larger scale.

RN - PICC, Full Time Days

Company: Mercy

Location: Springfield, Missouri

Posted Nov 08, 2024

Mercy Hospital Springfield offers a range of incentives for both new and experienced nurses, including sign-on bonuses, relocation assistance, education assistance, and comprehensive insurance. The hospital is recognized for its high-quality care, patient satisfaction, and commitment to safety and innovation, earning several hospital recognitions. Qualifications include graduation from an accredited nursing program, current RN license, and Basic Life Support certification.

Project Manager

Company: EAC Product Development Solutions

Location: Minneapolis–Saint Paul, MN

Posted Nov 08, 2024

The job description is for a Project Manager position at EAC, a company that provides product development solutions. The job involves managing multiple projects, developing project plans, and communicating with stakeholders. The company offers a competitive salary, benefits, and perks.

Head and Neck and Microvascular Surgeon

Company: Midwest Ear, Nose & Throat Specialists

Location: Saint Paul, Minnesota

Posted Nov 08, 2024

Midwest Ear, Nose, & Throat Specialists is offering a Fellowship-Trained Otolaryngologist position in Head and Neck Cancer and Microvascular Reconstruction Surgery. This role presents a great opportunity to join a well-established practice, working alongside another busy Fellowship-Trained Head and Neck Surgeon. The practice has strong relationships with Medical and Radiation Oncologists, and efficient patient care coordination. Benefits include state-of-the-art facilities, collaborative work with multiple specialists, and a competitive compensation structure. The Twin Cities, where the practice is located, offer a vibrant lifestyle with numerous amenities and job opportunities.

Partner Manager

Company: NetApp

Location: St. Louis, MO

Posted Nov 08, 2024

The Partner Manager - Central role at NetApp involves cultivating relationships with key partners in KS, MO, and NE, driving product and service sales through strategic partner engagement. The role requires strong relationship management, business planning, cross-functional coordination, and marketing & sales initiatives. The ideal candidate should have 12-15 years of B2B technology sales experience, proven success in achieving sales targets, and ability to travel. The compensation package is competitive, including a base salary range of 250,000 - 280,000 and a comprehensive benefits package.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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