Tech Jobs in SAINT LOUIS, Missouri

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Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Clinical Pharmacist - Joplin Hospital - FT/N (7on - 7off) / SIGN-ON BONUS $10,000

Company: Mercy

Location: Loma Linda, Missouri

Posted Nov 08, 2024

Mercy is offering a sign-on bonus of $10,000 for a position in a community-based hospital with advanced facilities. The role involves working with healthcare teams to provide drug therapy and serving as a drug information resource. Preferred candidates have two or more years of clinical experience and a PGY-1 residency. Required qualifications include a Bachelor's or Doctor of Pharmacy degree and a current pharmacist license. Mercy offers comprehensive benefits, including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, a positive outlook, and a strong sense of advocacy.

General or Advanced GI Opportunity in Central Missouri

Company: RosmanSearch

Location: Columbia, Missouri

Posted Nov 08, 2024

A renowned hospital in central Missouri is seeking a BC/BE Gastroenterologist. The successful candidate will join a top-rated hospital, recognized by Healthgrades and Forbes. The role offers a flexible schedule, modern equipment, strong referral base, and competitive compensation. The city, a college town, provides a lively downtown, outdoor activities, and a strong sense of community.

Internal Business Development Senior Sales Specialist

Company: Wells Fargo

Location: St. Louis, MO

Posted Nov 08, 2024

Wells Fargo is recruiting for a Senior Sales Specialist role in Equipment Finance- Middle Market Business Development. The role involves leading or participating in sourcing new clients or growing existing relationships, understanding clients' businesses, leading moderately complex transactions, collaborating with peers, and mentoring less experienced individuals. Required qualifications include 4+ years of secured or specialized lending sales experience, strong analytical skills, excellent communication skills, and the ability to work in a fast-paced environment. The position offers a competitive pay range, hybrid work schedule, and travel up to 25%. Wells Fargo values diversity and provides comprehensive benefits.

Dental Assistant

Company: Wexford Health Sources

Location: East St. Louis, Illinois

Posted Nov 08, 2024

The job posting is for a Dental Assistant PRN at Southwestern Illinois Correctional Center in East St. Louis, IL. The role involves assisting dentists in patient examinations and treatments, maintaining supplies and records, and ensuring cleanliness and sterilization of instruments. The position requires a high school diploma or equivalent, CPR certification, and preferably registration or certification by a professional association. Experience in a dental setting or correctional health care is preferred. The role involves working in a dental clinic within a correctional facility, with potential temperature extremes due to the facility's lack of air conditioning.

Lead Network Security Engineer

Company: Enterprise Mobility

Location: St. Louis, MO / Remote

Posted Nov 08, 2024

Enterprise Mobility, a leading global travel company, is seeking a Lead Network Engineer (Engineer 3) for their Network Security team. The role involves designing and developing security solutions, network segmentation, configuration of next-gen firewall platforms, and mentoring junior engineers. The ideal candidate should have a Bachelor's degree in a related field, 5+ years of engineering experience, and 3+ years in network and cloud security (AWS/AZURE). Preferred skills include experience with Palo Alto firewalls, scripting, and automation tools like Ansible and Terraform.

Physician Otolaryngology

Company: Community Health Systems

Location: Kirksville, Missouri

Posted Nov 08, 2024

Northeast Regional Medical Center in Kirksville, Missouri, is a 93-bed facility with over 75 physicians. It serves as the teaching hospital for the founding school of Osteopathic Medicine and has formed a strategic relationship with the University of Missouri-Columbia. The hospital is recruiting an Otolaryngologist and offers a combination of inpatient and outpatient roles. The position is suitable for Board Eligible physicians. The hospital features a Level III Trauma Center and a Certified Chest Pain Center. A competitive recruitment package is offered, including a rewarding salary, bonus, medical education debt assistance, and many additional benefits. Kirksville is known for its friendly community, three major educational institutions, and is the birthplace of Osteopathic Medicine. The area offers a variety of recreational activities, shopping, dining, and housing options.

RN-Trauma Specialist (PT Nights)

Company: Mercy

Location: Springfield, Missouri

Posted Nov 08, 2024

The Trauma Nurse Clinician plays a crucial role in managing trauma patients, from initial activations to coordinating care among sub-specialist physicians. They are expected to have excellent communication skills, handle stressful situations, and manage multiple tasks. The position requires a graduate of an accredited nursing program, a current RN license, and three years of clinical experience in ED, ICU, EMS, or Flight settings. TNCC, ACLS/PALS certifications are mandatory within specific timeframes. Preferred skills include trauma registry knowledge, Excel proficiency, and relevant certifications like TCRN, CEN, CCRN. The employer offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds.

Clinical Pharmacist - St Louis Hospital - FT

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 08, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The role involves working with healthcare teams to provide safe drug therapy, serving as a drug information resource, and maintaining a positive outlook. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, and committed to delivering excellent care.

Pharmacy Technician

Company: CVS Health

Location: St. Louis, MO

Posted Nov 08, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing pharmacy workstations, and ensuring regulatory compliance. New hires must complete a training program and meet state board of pharmacy requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, and well-being programs.

RN - Nurse - Neuro, PT, Nights

Company: Mercy

Location: Festus, Missouri

Posted Nov 08, 2024

Mercy Hospital Jefferson Neuro Unit offers numerous incentives for RNs, including sign-on bonuses, loan forgiveness, and tuition reimbursement. They provide a supportive environment for career growth, with benefits like shift differential pay, merit increases, and comprehensive health coverage. The Neuro/Pulmonary/Stroke Unit, also known as 2 East, handles complex cases involving COPD, respiratory failure, asthma, pneumonia, and stroke. Nurses maintain a 1:4 or 1:5 patient ratio, ensuring continuous vigilance and care.

LPN- Med/Surg 7B (Nights)

Company: Mercy

Location: Springfield, Missouri

Posted Nov 08, 2024

Mercy Springfield's Medical Surgical (Med-Surg) unit offers a comprehensive range of nursing services. This unit, which forms the foundation of nursing, manages acute and chronic medical conditions across a wide spectrum of diagnoses. New graduates can benefit from a $2,000 sign-on bonus, while experienced LPNs can earn up to $10,000. Additional incentives include $3,000 relocation assistance for full-time employees and a frontloaded PTO of up to 40 hours. The unit specializes in managing complex diagnoses and patient needs, providing ample learning opportunities. It serves a diverse patient population, including those with infectious diseases, wounds, pneumonia, sepsis, COPD, diabetes, gastro-intestinal conditions, and post-surgical patients. The unit also coordinates management of patients requiring surgical interventions, EGD, colonoscopy, outpatient infusion/chemo, and anti-coagulation therapies. Qualifications include graduation from a State Board of Nursing approved Practical Nursing Program, current LPN licensure with the Missouri State Board of Nursing, and a current American Heart Association Healthcare Provider card.

Interventional Endoscopist

Company: HealthPartners

Location: Saint Paul, Minnesota

Posted Nov 08, 2024

HealthPartners is seeking a BC/BE advanced endoscopist/gastroenterologist for a full-time position in St. Paul, MN. The role involves outpatient procedural and clinic services at multiple locations, including HealthPartners Specialty Center, Anoka Riverway Clinic, Lakeview Hospital Procedure Center, Hudson Hospital Procedure Center, and a new Woodbury, MN clinic. The physician will have EUS/ERCP experience and be capable of advanced techniques like BarrX, single balloon colonoscopy, Axios stenting, and EMRs. They will participate in advanced endoscopy coverage for Regions Hospital and inpatient general gastroenterology service, covering call every 3rd week and 1 weekend per month. The role also includes completing screening and diagnostic procedures at St. Paul and Anoka, MN sites. Experience with Epic and MN/WI licensure is preferred. HealthPartners is an integrated health care organization, committed to sustainability, and recognized as a top health system.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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