Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

An Interventional Cardiologist Is Wanted for Locum Tenens Assistance in Missouri WBY# JOB-2996927

Company: Weatherby Healthcare

Location: Osage Beach, Missouri

Posted Nov 07, 2024

Weatherby Healthcare offers a locum tenens opportunity in Interventional Cardiology at Osage Beach, Missouri. The assignment includes 24-hour shifts, 10 patients per day, and 1-4 procedures. Weatherby provides support, competitive compensation, pre-paid travel and housing expenses, and malpractice insurance. The company, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Lab Support Technician - Full Time

Company: Mercy

Location: Festus, Missouri

Posted Nov 07, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, as recognized by Modern Healthcare Magazine. The Laboratory Support Technician (LST II) role involves providing laboratory support, acquiring specimens for testing, and maintaining HIPAA confidentiality. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and advocates for excellent care.

Ultrasound Technologist III - Full Time - Loan Repay

Company: Mercy

Location: Aurora, Missouri

Posted Nov 07, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer rewarding careers that align with individual skills and heart. The company provides incentives like a Loan Repayment Assistance Program up to $20,000 for eligible Imaging co-workers. The role involves providing diagnostic sonograms and assisting radiologists in procedures. Qualifications include education from a school of sonography or registered technologist, relevant experience, and certifications from ARDMS or ARRT. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They foster a supportive community and encourage innovation in healthcare.

Neonatologist

Company: Pediatrix Medical Group

Location: Kansas City, Missouri

Posted Nov 07, 2024

Pediatrix Medical Group is seeking a BC/BE neonatologist for a full-time position in Kansas City, Missouri. The role involves providing in-house coverage for Saint Luke's Health System, which includes three NICUs with advanced ventilator support. The main unit is a regional perinatal referral center with a 49-bed Level-IIIB NICU, handling over 450 annual admissions. The city, known as the 'City of Fountains', is recognized for its affordable cost of living, low crime rates, renowned schools, and vibrant culture. The compensation package is competitive, offering sign-on bonuses, relocation, tuition reimbursement, and various benefits.

Independent CRNA for Southern IL No Call, Nights or Weekends - ALL CRNA Team CPH# JOB-2996562

Company: CompHealth

Location: East Saint Louis, Illinois

Posted Nov 07, 2024

CompHealth is offering a full-time CRNA position in East Saint Louis, Illinois. This role involves working in an all-CRNA team, providing a variety of cases and regionals (with training provided). The schedule is M-F with no call, nights, or weekends, ensuring a good work-life balance. The location is less than an hour from St. Louis, MO. CompHealth will assist with salary negotiation, contract details, interviews, and licensing. They offer both W2 and 1099 options.

Cardiology Advanced Practice Clinician in Kansas City, MO

Company: TeamHealth

Location: 14430 Metcalf AveKansas City, Missouri 66223

Posted Nov 07, 2024

TeamHealth is offering a full-time position for a cardiology advanced practice clinician (APC) in Kansas City, Missouri. The role involves providing quality, compassionate care through weekday rounding at skilled nursing facilities. The position is benefits eligible with a competitive compensation range of $133,642 to $145,803 annually. No night call or weekend call is required. Additional perks include a highly competitive base salary, uncapped monthly bonuses, guaranteed paid time off, and an excellent benefits package. TeamHealth also provides extensive support, training, and growth opportunities.

Locums PA - Cardiovascular/Cardiothoracic Surgery Job in Missouri WBY# JOB-2996913

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 07, 2024

Weatherby Healthcare is offering a Physician Assistant position in Missouri. The role involves working with 8-10 patients per day in a clinic setting, performing procedures like vein harvesting, ECMO, chest tube placement & removal, and ICU & floor rounding/coverage. The company provides benefits such as health, vision, dental, and 401(k) retirement benefits, competitive compensation, paid malpractice insurance, and support for transportation and housing expenses. The position requires ACLS and BLS certifications, DEA, and COVID-19 vaccination. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Associé/Associée de Magasin Marshalls Homesense Plaza des Laurentides

Company: The TJX Companies, Inc.

Location: Saint-Jérôme, Canada

Posted Nov 07, 2024

Jenna enjoys collaboration at TJX, appreciating the use of individual strengths to achieve common goals. Employees benefit from a unique, inclusive culture, specific training, and TJX Canada merchandise discounts. The job involves customer service, inventory management, and maintaining fitting rooms. No high school diploma or equivalent required, but excellent customer service, communication, and time management skills are necessary. Salary range is $15.75 - $16.75 per hour. TJX Canada values diversity and inclusion, offering opportunities for continuous learning and growth.

RN - Nurse - Wound Center, Full-time

Company: Mercy

Location: Festus, Missouri

Posted Nov 07, 2024

Mercy Hospital Jefferson in Festus, Mo., is offering a nursing position with a positive work environment. The hospital, a 251-bed acute care facility, is known for its compassionate care and exceptional service. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating care with other departments. Benefits include shift differential pay, annual merit increases, tuition reimbursement, comprehensive health benefits, paid parental leave, a 401k with employer match, and free parking. The hospital specializes in wound care, offering a wide range of services including hyperbaric oxygen therapy. Required qualifications include a nursing degree, current RN license, 2 years of nursing experience, and Basic Life Support certification.

RN - Med/Surg - Full Time - Days

Company: Mercy

Location: Washington, Missouri

Posted Nov 07, 2024

Mercy Hospital Washington is offering a full-time position in the Med/Surg department with a 36-hour workweek on the day shift. The hospital is providing significant sign-on bonuses: $13,000 for experienced RNs and $10,000 for graduate nurses. Additional incentives include a Stay Premium Program, Education Assistance, Tuition Reimbursement, comprehensive insurance, PTO/Vacation Time, and Employer-Matched Retirement Funds. The unit, a 30-bed Medical/Surgical Unit, handles a variety of patient cases with a nurse-to-patient ratio of 1:6. The core values of the team are teamwork and accountability.

Emergency Medicine Physician Assistant or Nurse Practitioner Opportunity On Beautiful Lake Michigan

Company: Envision Physician Services

Location: Saint Joseph, Michigan

Posted Nov 07, 2024

Envision Physician Services is recruiting for a full-time Nurse Practitioner or Physician Assistant in St. Joseph, Michigan. The role requires at least one year of Emergency Medicine experience. The position offers a high volume of patient encounters, works in a Level III Trauma Center, and involves 12-hour shifts with 24-hour coverage daily. Benefits include comprehensive health, dental, vision, 401K with match, and CME allowance. Envision Physician Services is a leading national medical group providing various services to over 1,800 clinical departments in 45 states.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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