Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Staff Assistant

Company: Wexford Health Sources

Location: East St. Louis, Illinois

Posted Nov 06, 2024

Wexford Health Sources, Inc., a leading correctional health care provider, is seeking a Staff Assistant for their Southwestern IL Correctional Center in East St. Louis, IL. The full-time position offers a competitive benefits package including annual increase, 40 paid days off, medical insurance, dental and vision coverage, a 401(k) plan with 50% match, and short-term disability. The role involves clerical and technical duties, preparing reports, answering telephones, maintaining filing systems, scheduling appointments, and coordinating clerical assistance for Telehealth clinics. The successful candidate will be part of a team dedicated to healing and rehabilitating incarcerated patients, making a significant difference in their lives.

Physician Assistant – Family Medicine

Company: VillageMD

Location: Missouri City, Texas

Posted Nov 06, 2024

VillageMD is recruiting a Physician Assistant for a primary care practice in Missouri City, Texas. The ideal candidate should have 2+ years of outpatient clinical experience, be comfortable working autonomously, and possess strong communication skills. They must also be licensed, registered with DEA, and enrolled in Medicare/Medicaid. Familiarity with Athena EMR and Microsoft Office is preferred.

Lab Support Technician - Nights, Full Time *Sign On*

Company: Mercy

Location: Joplin, Missouri

Posted Nov 06, 2024

Mercy is offering a Laboratory Support Technician (LST II) position with a $2,000 sign-on bonus. The role involves supporting laboratory reports, data, and scheduling functions, requiring excellent customer service and HIPAA compliance. Candidates must have 6 months of phlebotomy or clinical lab experience. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, and a positive outlook, offering opportunities for career growth and innovation in healthcare.

Physician - Pediatric Hospitalist - ED & Nursery - Cardinal Glennon - Part Time

Company: SSM Health

Location: St. Louis, Missouri

Posted Nov 06, 2024

A part-time Pediatric Hospitalist position is available in the St. Louis Metro Area. The role involves providing Pediatric ED coverage, rounding on newborns, attending c-sections/deliveries, and 12-hour shifts day/night. NRP Certification is required. The position offers professional fulfillment and various needs including PRN, Part Time, and Full Time. Locations are throughout the St. Louis Metropolitan area. The physician will be responsible for admission, management, and discharge of pediatric patients, and will respond to requests from the facility's Emergency Department. St. Louis, Missouri, is highlighted as an affordable city with diverse neighborhoods, cultural opportunities, and excellent educational institutions. It's home to world-renowned attractions like the St. Louis Arch and the St. Louis Cardinals.

Physician - Pediatric Hospitalist - PRN - Glennon Care

Company: SSM Health

Location: Bridgeton, Missouri

Posted Nov 06, 2024

The text describes a job opportunity for a Pediatric Hospitalist in the St. Louis Metro Area. The role involves providing pediatric services at designated hospitals or program sites, managing patient admissions, discharges, and evaluations. The physician will also respond to emergency department requests, attend deliveries, and collaborate with other healthcare professionals to ensure continuity and timeliness of care.

Cardiac Sonographer PRN

Company: Mercy

Location: Saint Louis, Missouri

Posted Nov 06, 2024

Mercy South Non-invasive Cardiology is seeking a Cardiovascular Sonographer with over two years of experience. The role involves providing exceptional service, performing routine exams, stress tests, and special procedures. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, and a positive outlook, promoting career advancement and community growth.

Seeking General Surgeon to join Experienced Team in Jefferson City, MO.

Company: SSM Health

Location: Jefferson City, Missouri

Posted Nov 06, 2024

SSM Health is expanding its General Surgery practice at St. Mary's Hospital in Jefferson City, MO, seeking a full-time General Surgeon. The role offers a broad-based surgical practice, including minimally invasive surgery and endoscopy, with an excellent onboarding process and two-year salary guarantee. The position is fully integrated into the Epic EMR system for improved care coordination. Jefferson City, named 'Most Beautiful Small Town in America', offers a high quality of life with easy access to big-city amenities and natural attractions like Lake of the Ozarks.

Physician - Child Adolescent Psychiatrist - Full Time Academic - SLUCare Physician Group

Company: SSM Health

Location: St. Louis, Missouri

Posted Nov 06, 2024

SLUCare Physician Group, the academic medical practice of SSM Health in St. Louis, boasts over 600 healthcare providers across various specialties. Their physicians are highly trained, with national and international experts recognized for research and medical innovations. SLUCare offers a full faculty academic appointment at Saint Louis University, competitive salary with exceptional benefits, and a balanced mix of inpatients and outpatients. The campus houses both hospital and outpatient offices, and physicians use the EPIC EMR system. In addition to patient care, SLUCare physicians educate future healthcare professionals, guided by their Catholic Jesuit tradition.

Pharmacy Technician - Dierbergs Wildwood, PRN - As Needed

Company: Mercy

Location: Wildwood, Missouri

Posted Nov 06, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and talents, and have been recognized as a 'Top 100 Place to Work' by Modern Healthcare Magazine. The Pharmacy Technician role involves assisting pharmacists in preparing, compounding, and dispensing medications, and requires a high school diploma, registration with the Missouri Board of Pharmacy, and preferably 1 year of relevant experience. Mercy provides comprehensive benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They emphasize a positive work environment, collaboration, and a commitment to delivering excellent care.

NP - Internal Medicine - Same Day

Company: Park Nicollet

Location: St. Louis Park, Minnesota

Posted Nov 06, 2024

Park Nicollet Clinics in St. Louis Park is recruiting a Nurse Practitioner for their Internal Medicine team. The role involves providing primary care, performing acute in-clinic procedures, and being part of a supportive, committed team. Benefits include competitive insurance, 401k with company match, CME reimbursement, and a well-being program. The location offers a diverse community with numerous parks, outdoor spaces, and proximity to Minneapolis. Park Nicollet, a HealthPartners member, values inclusivity, diversity, and health equity.

System Clinical Pharmacy Manager - Administration/St. Louis - FT

Company: Mercy

Location: Chesterfield, Missouri

Posted Nov 06, 2024

The System Clinical Pharmacy Manager role at Mercy is focused on providing strategic leadership and overseeing clinical pharmacy services across the health system. The primary goal is to ensure high-quality, evidence-based pharmaceutical care for patients, optimizing medication therapy outcomes, and promoting safe and effective medication use. Key responsibilities include leading and managing clinical pharmacy teams, developing policies, and delivering clinical services.

Sr Marketing Representative

Company: EAC Product Development Solutions

Location: Minneapolis–Saint Paul, MN

Posted Nov 06, 2024

The job description is for a Senior Marketing Representative at EAC Product Development Solutions. The role involves developing and executing marketing campaigns, creating high-quality content, and collaborating with cross-functional teams. The job requires a bachelor's degree in marketing or a related field, 5+ years of experience in content creation or strategic marketing, and proficiency in the Adobe Suite of products.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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