Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Automation Engineer III

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 02, 2024

Edward Jones is investing heavily in technology, particularly in cloud-based architecture and emerging technologies. They are seeking a talented automation engineer to join their Technology Digital Account Solutions (DAS) team. The role involves collaborating with software and support teams to enhance SRE and QE maturity. Key responsibilities include collecting and escalating information from other DAS product teams, supporting and increasing DAS QE automation, and designing, coding, testing, deploying, and maintaining testing automation solutions. The ideal candidate should have 5+ years of experience in test automation, expertise in tools like Selenium, SoapUI, and Jira, and strong communication skills.

Senior Financial Analyst III

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 02, 2024

Edward Jones is offering a full-time position in their Canada Finance department. The role involves preparing annual financial statements according to IFRS, coordinating audits, and creating executive-level financial reports. The successful candidate will also identify efficiency improvements, present financial reports, and participate in cross-functional teams. The company provides a comprehensive benefits package including health insurance, retirement plan, and paid time off. Minimum requirements include a bachelor's degree, 6+ years of relevant experience, and advanced financial analysis skills. Preferred qualifications include an advanced degree, CPA, and IFRS experience.

Teacher at West St. Paul KinderCare

Company: KinderCare Learning Companies

Location: Saint Paul, MN

Posted Nov 02, 2024

KinderCare Learning Companies, an early childhood education provider, seeks a Teacher to join their team in West Saint Paul, Minnesota. The role involves implementing curriculum, creating a nurturing environment, partnering with parents, and supporting center success. Qualifications include customer service skills, CPR/First Aid certification, meeting state-specific requirements, and English proficiency. Benefits include discounted child care, medical/dental insurance, mental health support, and more. KinderCare is committed to equal opportunity employment.

QC Scientist I

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Nov 02, 2024

Thermo Fisher Scientific is seeking a candidate with a Bachelor's degree in a relevant field and at least 1 year of experience in a regulated environment. The role involves using analytical tools like HPLC and UPLC for GMP manufacturing, stability testing, and developing new techniques. The candidate will work in a cGMP environment, compile data, and collaborate with team members. Key skills include in-depth knowledge of analytical techniques, MS Office proficiency, and strong organizational skills. The company offers competitive remuneration, healthcare benefits, and a positive company culture.

Associate Director - Private Clients

Company: CSC

Location: Saint Helier, Jersey

Posted Nov 02, 2024

CSC is seeking a Client Director for a permanent, hybrid role in Jersey. The successful candidate will manage a portfolio of private clients, contribute to regulatory and compliance policies, and oversee client company management. They will also lead a team, ensuring adherence to CSC values and delivering effective communication. The role requires a JFSC Category A employee with a Table 4 qualification, team leadership skills, and excellent interpersonal skills.

Senior Manager, Software Development, Spectrum Enterprise

Company: Spectrum

Location: St. Louis, MO

Posted Nov 02, 2024

Spectrum Enterprise is seeking a Senior Manager of Software Development to lead a team of talented Pega developers in building an enterprise-wide application. The role involves guiding a team, ensuring high-quality client experiences, hiring and mentoring high-performing teams, and managing the software development lifecycle. The ideal candidate should have extensive leadership and software engineering experience, a Bachelor's degree in a related field, and expert understanding of software engineering principles. Preferred skills include Agile methodologies, PEGA Products, AWS, microservices, and Netflix OSS tools. Spectrum Enterprise offers a diverse, learning culture with dynamic growth opportunities and comprehensive benefits.

Pharmacy Technician

Company: CVS Health

Location: Saint Michael, MN

Posted Nov 02, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing pharmacy workstations, and ensuring regulatory compliance. New hires must complete a training program and meet state board of pharmacy requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, and well-being programs.

IT Solution Architect - Microsoft 365

Company: Enterprise Mobility

Location: St. Louis, MO / Remote

Posted Nov 02, 2024

Enterprise Mobility, a leading global travel company, is seeking an IT Solution Architect. The role involves leading strategic activities in the dynamic IT environment, collaborating with engineers and managers, and providing technical leadership. The successful candidate will have extensive experience with Microsoft 365 products, security platforms, and cloud workloads. They will also mentor less experienced team members and contribute to the development of technology solutions. The position offers a competitive package, including market-competitive pay, comprehensive healthcare, and flexible work arrangements.

Plasma Protein Workflow Advisor and EXENT Product Manager

Company: Thermo Fisher Scientific

Location: Saint-Égrève, France

Posted Nov 02, 2024

Thermo Fisher Scientific Inc. is seeking a Workflow Advisor & EXENT Product Manager. This role involves supporting the France Benelux Protein Island strategy, optimizing protein workflows, and recommending patient protein profile reporting methods. The candidate will also drive the new EXENT® system portfolio, focusing on market analysis, product positioning, and customer engagement. The position requires a scientific degree, experience in product management, and strong analytical skills. The company offers a competitive salary, professional development, and the chance to work with a leading company in Protein Diagnostics.

Account Manager - AEC

Company: Esri

Location: St. Louis, MO

Posted Nov 02, 2024

Esri is seeking a customer-oriented, collaborative team player with experience in enterprise sales or consulting to join their AEC account team. The role involves building relationships, understanding customer needs, and implementing location strategies. The ideal candidate should have a strong understanding of the AEC industry, GIS, and new technology trends. They will work closely with a team to optimize and expand adoption of Esri technology, identify growth opportunities, and share expertise. Esri offers a competitive total rewards strategy, including health benefits, 401(k) programs, and opportunities for professional growth.

Associate Analyst I - Proprietary Funds

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 02, 2024

Edward Jones is seeking an Associate Analyst I/II for the Portfolio Solutions Team (PST) within the Wealth Management Advice and Solutions Division. The role involves supporting the management of Bridge Builder mutual funds and Edward Jones Money Market Fund, with potential exposure to all PST's investment responsibilities. The ideal candidate will have a finance or accounting degree, be progressing towards CFA designation, and have 2-4 years of experience in manager selection, due diligence, and multi-asset portfolios. Proficiency in various software programs is required. Edward Jones offers a comprehensive benefits package including health insurance, retirement plans, and flexible spending accounts.

Pharmacy Technician

Company: CVS Health

Location: Saint Charles, MD

Posted Nov 02, 2024

CVS Health is inviting applications for Pharmacy Technicians, emphasizing their commitment to human-centric healthcare. The role involves delivering compassionate care, managing prescriptions, and ensuring regulatory compliance. New hires must complete a training program and satisfy state licensing requirements. The position offers opportunities for career growth and a range of benefits, including medical, dental, vision, 401(k), life insurance, disability benefits, well-being programs, and more. CVS Health values accountability, caring, collaboration, innovation, and integrity.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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