Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Lead Independent Testing Officer - Customer Remediation Validation Data Management (SQL/SAS)

Company: Wells Fargo

Location: St. Louis, MO

Posted Nov 01, 2024

Wells Fargo is seeking a Lead Independent Testing Officer in Independent Testing & Validation (IT&V) as part of Corporate Risk. The role involves leading and managing multiple projects, developing and implementing processes for review activities, and partnering with analytic and business resources. The ideal candidate should have 5+ years of Independent Testing experience, strong analytical skills, and the ability to work under pressure in a dynamic environment. The position offers a competitive pay range and comprehensive benefits.

Physician Urology

Company: Community Health Systems

Location: Poplar Bluff, Missouri

Posted Nov 01, 2024

Poplar Bluff Regional Medical Center is offering an exceptional opportunity for a Board-Certified Urologist. The center, a 412-bed facility with cutting-edge technology including 2 Da Vinci Robots, seeks a robotically trained candidate for advanced procedures like Prostate and Nephrectomy. The position offers anesthesia support, efficient outpatient services, and a supportive environment. The community in Poplar Bluff, with a population of 33,000 and a service area of over 125K, boasts recreational delights, educational excellence, and a quality living environment. The recruitment package includes competitive compensation, holistic benefits, relocation support, and potential bonuses. The center also offers educational support and a stipend for remaining training.

RN - Cardiac Cath Lab Full Time Days

Company: Mercy

Location: Springfield, Missouri

Posted Nov 01, 2024

Mercy Health is offering competitive benefits and sign-on bonuses for RNs based on their experience, ranging from $5,000 to $20,000. They provide up to 80 hours of PTO and up to $7,000 relocation assistance. The role involves utilizing the nursing process, maintaining patient care, and coordinating with other departments. Qualifications include a nursing degree, current RN license, and BLS certification. Mercy Health is known for its compassionate care, exceptional service, and being named in Modern Healthcare Magazine's 'Top 100 Places to Work'.

Outside Sales Rep - St. Louis, MO

Company: Restaurant365

Location: St. Louis, MO

Posted Nov 01, 2024

Restaurant365, a SaaS company revolutionizing the restaurant industry, is seeking a full-time Outside Sales Rep for a remote position based in St. Louis. The role involves driving sales, building connections, and achieving greatness by introducing their innovative platform to restaurant groups. The company offers a competitive OTE, comprehensive benefits including medical, retirement, equity, and unlimited PTO, and fosters a culture of empowerment and career growth.

Registered Nurse (Non-Exempt) (10013N)

Company: Mercy

Location: Joplin, Missouri

Posted Nov 01, 2024

Mercy is offering a Sign On Bonus for RN positions, paid out over 2 years. Eligible RNs who graduated within the last 12 months can receive up to $20,000 in student loan re-payment assistance. Benefits include PTO, shift differentials, health/dental/vision, paid parental leave, 401k with employer match, and more. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, and coordinating care with other departments. Qualifications include a current RN license, preferred 1 year of RN experience in OR, and various certifications. Mercy offers great benefits including comprehensive health coverage, PTO, tuition reimbursement, and retirement funds.

Executive Assistant

Company: Enterprise Mobility

Location: St. Louis, MO

Posted Nov 01, 2024

Enterprise Mobility, a leading provider of mobility solutions, is seeking an Executive Assistant for its Global Strategy team. The role involves supporting the SVP of Strategic Initiatives and his team, managing complex calendars, coordinating meetings and travel, conducting research, and overseeing administrative functions. The position offers a competitive benefits package and is located at the Corporate Headquarters in Clayton, MO with a hybrid schedule. The ideal candidate should have at least 5 years of administrative experience, proficiency in MS Office, and strong communication and detail-oriented skills.

Oral Surgeon

Company: Nuvia Dental Implant Center

Location: St. Louis, Missouri

Posted Nov 01, 2024

Nuvia Dental Implant Center is seeking a skilled Oral Surgeon for their St. Louis, MO location. The ideal candidate will join a team using cutting-edge technology to deliver permanent teeth in 24 hours. Nuvia offers a generous per arch rate, steady stream of cases, and a bonus structure based on volume. They provide CRNA, sedation, and secure airway for every case, and handle permanent next-day restoration. The position is flexible, allowing for part or full-time on contract, with no non-compete or restrictive covenants. Nuvia offers hands-on complex case training, peer-to-peer case reviews, and mentorship. The Surgeon will perform dental implant surgery, work closely with the restorative doctor, and examine, diagnose, and provide treatment plans to patients. Success is defined by delivering excellent clinical care and executing the proposed treatment plan.

Registered Respiratory Therapist

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 01, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, and have been recognized as a 'Top 100 Place to Work' by Modern Healthcare Magazine. Mercy provides a Loan Repayment Assistance Program of up to $20,000 for Respiratory co-workers. The role involves direct patient care in respiratory care, consulting physicians, and acting as an advanced resource person. Qualifications include a CoArc approved Respiratory Care program graduation, state licensure, RRT credential, and preferably ACLS and critical care experience. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They promote a supportive community, innovation, and collaboration.

LPN - Ortho Neuro - FT/ Shift TBD

Company: Mercy

Location: Joplin, Missouri

Posted Nov 01, 2024

Mercy is offering a Sign On Bonus for a Licensed Practical Nurse (LPN) position. The role involves providing patient care under supervision, coordinating with other departments, and maintaining patient rights and confidentiality. The company values compassionate care and exceptional service, offering great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. Mercy is committed to a supportive community, innovation, and growth, seeking candidates with a positive outlook, strong advocacy, and a collaborative spirit.

Cardiothoracic Surgeon

Company: Department of Veterans Affairs

Location: Columbia, Missouri

Posted Nov 01, 2024

Harry S Truman VAMC in Columbia, MO is recruiting a Cardiothoracic Surgeon. Columbia, located between St. Louis, Kansas City, and the Lake of the Ozarks, offers a blend of small-town charm and big city amenities. The position offers a competitive salary, comprehensive benefits including 50-55 days of paid time off, retirement plans, and free liability protection. The surgeon will be responsible for comprehensive examinations, diagnosis, treatment plans, and surgical procedures. They will also provide medical education, counseling, and collaborate with other healthcare providers. The facility promotes diversity and inclusion, fostering a teamwork environment.

Lead Payroll Analyst - Finance

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 01, 2024

Edward Jones is seeking a Lead Payroll Analyst for their Compensation Operations Department. The role involves managing day-to-day payroll processing, leading complex projects, and ensuring compliance with regulations. The ideal candidate should have a Bachelor's Degree or equivalent experience, 6 years of payroll experience, and relevant certifications. The position requires strong collaboration skills, system knowledge, and the ability to mentor team members. Edward Jones offers a comprehensive benefits package including health insurance, retirement plans, and flexible spending accounts.

Radiologic Technologist Full-time Evenings

Company: Mercy

Location: Saint Louis, Missouri

Posted Nov 01, 2024

Mercy is a top employer offering a range of benefits including comprehensive health coverage, tuition reimbursement, and retirement funds. They value compassionate care and exceptional service, providing careers that align with individual skills and heart. Mercy offers incentives like a Loan Repayment Assistance Program up to $20,000 for Imaging co-workers. The role involves performing radiographic procedures, requiring technical skills and understanding of anatomy. Mercy's supportive community fosters innovation and excellent care, making it a great fit for those who value collaboration and advocacy.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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