Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Senior Substation Engineer

Company: LUZCO Technologies LLC

Location: St. Louis, MO

Posted Oct 15, 2024

The company LUZCO is looking for a candidate to join their team as a substation PampC design engineer. The job requires advanced understanding of protection and control fundamentals, proficiency in design of protection schemes, and ability to lead a team of engineers and designers. The company offers a relaxed work environment, flexible schedule, and opportunities for growth and development.

Family Medicine Physician Assistant needed for FQHC in Missouri! Up to $25K Sign-On! CPH# JOB-2990802

Company: CompHealth

Location: Rolla, Missouri

Posted Oct 16, 2024

A community health clinic in Rolla, Missouri is offering a Family Nurse Practitioner or Physician Assistant position with a 4-day work week, full benefits, sign-on bonus, relocation assistance, and government loan repayment. The city of Rolla is described as affordable and vibrant, offering various activities and attractions for all ages. CompHealth, a healthcare staffing company, is facilitating the recruitment process.

RN - Cardiac Med, FullTime/ Shift TBD

Company: Mercy

Location: Joplin, Missouri

Posted Oct 16, 2024

Mercy is offering a Sign On Bonus and student loan re-payment assistance for RNs who graduated within the last 12 months. The position includes benefits such as PTO, shift differentials, Mercy Loyalty Pay Program, health/dental/vision, paid parental leave, 401k with employer match, free Mercy Nurse On-Call, free life insurance, AD&D coverage, short term disability benefits, referral bonus opportunity, and a Clinical Ladder career development plan. The role involves utilizing the nursing process to provide patient care, maintaining professional accountability, evaluating care effectiveness, coordinating patient care, and maintaining patient rights and confidentiality.

Radiologist (Diagnostic or Women's Health) opening in Missouri

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Oct 16, 2024

A full-time permanent position for a Radiologist (Diagnostic or Women's Health) is available in Joplin, Missouri. The role involves working with a hospital-employed group of four board-certified Radiologists, utilizing advanced equipment including PET and MRI. Diagnostic Radiologists will handle general radiology and basic interventional cases, while Women's Imaging specialists will work primarily in the Women's Pavilion, a Breast Imaging Center of Excellence. The community offers a high quality of life with big-city amenities, a low cost of living, and numerous recreational activities. The position comes with teaching opportunities, a generous salary, and bonus potential.

Tool & Die Maker

Company: Crown Cork & Seal USA

Location: Missouri City, TX

Posted Oct 16, 2024

Crown Holdings, Inc. is a global leader in packaging solutions for consumer goods, with a focus on innovation and value for brand owners, retailers, and consumers. The company's Beverage Division specializes in aluminum cans for beverages, offering a large printable surface area and various sizes, shapes, and decorating options. The Tool & Die Maker position at the Sugar Land, Texas manufacturing location involves maintaining high-speed manufacturing equipment, performing repairs, and managing tooling inventories. The ideal candidate should have 5-10 years of manufacturing experience, knowledge of materials and tools, and strong problem-solving skills. The role requires working various shifts, including nights, weekends, and overtime, and lifting up to 50 pounds. The company offers competitive benefits, including a sign-on bonus, medical, dental, vision, pension, 401k plan, and tuition reimbursement.

Locums Emergency Medicine Nurse Practitioner or Physician Assistant

Company: AAS Healthcare Staffing

Location: Saint Johns, Michigan

Posted Oct 16, 2024

AAS Healthcare Staffing is seeking a Locums Emergency Medicine Nurse Practitioner or Physician Assistant for a fast-paced emergency department in St. Johns, MI. The ideal candidate should have experience in emergency care, be comfortable with a diverse patient population, and possess the ability to function efficiently in a Level IV trauma center. The role involves working two shifts per week, from 11:00 AM to 11:00 PM, with an average of 45 patients seen in a 24-hour period and 5 to 7 admitted daily. St. Johns, located in Michigan, offers a welcoming community atmosphere with modern amenities and small-town charm. The hospital's emergency department plays a crucial role in the region, providing essential care to the community.

RN - Float Pool - Full Time - Nights

Company: Mercy

Location: Washington, Missouri

Posted Oct 16, 2024

Mercy Hospital Washington is offering a full-time RN Float Pool position with a base pay plus incentives. The role involves working nights and requires 1-year of RN experience. The hospital provides a range of benefits including a sign-on bonus up to $20,000, relocation assistance up to $3,000, education assistance, and retirement funds. The RN will float between Emergency Department, ICU, Cardiac Telemetry, Medical Surgical, and Medical Surgical- Adults & Peds departments.

Product Manager

Company: Livefront

Location: Minneapolis–Saint Paul, MN

Posted Oct 16, 2024

The job posting is looking for an outstanding Product Manager to join their team. The ideal candidate is passionate about innovative new ideas, has a track record of leading high-profile product initiatives, and is a self-starter who thrives in autonomy. The company values a work environment where respect, mutual trust, and egoless collaboration are paramount.

Plastic Surgeon

Company: Midwest Ear, Nose & Throat Specialists

Location: Saint Paul, Minnesota

Posted Oct 16, 2024

Midwest Facial Plastic Surgery, a reputable facial aesthetic center, plans to expand its services to include Full Body Plastic Surgery. With over 800 loyalty program members, they aim to retain cosmetic body surgery business in-house. The practice has three office locations, is constructing a fourth, and co-owns two outpatient surgery centers, ensuring ample operating room time. The partnership track offers ownership in the core medical practice, real estate, and other passive income streams, typically lasting 24-36 months.

Product Strategist

Company: Livefront

Location: Minneapolis–Saint Paul, MN

Posted Oct 16, 2024

The job posting is looking for a Product Strategist to join their team. The ideal candidate has experience in product management, is curious about technology, and can align technologies to problems. The company values respect, mutual trust, and egoless collaboration.

LPN - Med Tele Full Time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Oct 16, 2024

The job posting offers a sign-on bonus ranging from $2,000 to $10,000 based on years of experience, education assistance, tuition reimbursement, relocation assistance, and various differentials for weekend and night shifts. Benefits include comprehensive insurance, retirement funds, and opportunities to work with complex diagnoses and patient needs in a fast-paced environment.

Family Nurse Practitioner or Physician Assistant needed for FQHC in Missouri! Up to $25K Sign-On! CPH# JOB-2990797

Company: CompHealth

Location: Rolla, Missouri

Posted Oct 16, 2024

A family health clinic in Rolla, Missouri is offering a full-time position for a Family Nurse Practitioner or Physician Assistant. The role includes a 4-day work week, competitive pay, and generous benefits such as a sign-on bonus, relocation assistance, and NHSC Loan Repayment. Salem, Missouri, where the clinic is located, is described as affordable and vibrant, offering various activities and attractions for all ages. CompHealth, the recruitment agency, is known for its excellent customer service and personalized job matching.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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