Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Sr. DevOps Engineer

Company: Centene Corporation

Location: St. Louis, MO

Posted Oct 04, 2024

The job posting is for a software development position at Centene, a national organization. The job involves designing, developing, and implementing complex enterprise software solutions. The company offers competitive benefits, including a flexible work schedule and tuition reimbursement.

Allstate Sales Agent

Company: Allstate

Location: Saint John, Canada

Posted Oct 04, 2024

Allstate is seeking a results-driven, experienced sales agent to join their team. The role involves networking, understanding customer needs, and providing comprehensive insurance policies. The company offers a commission-driven environment, paid vacation, quarterly bonuses, and onboarding training. Allstate values customer centricity, digital literacy, inclusive leadership, learning agility, and results-orientation. The company has a strong commitment to diversity and inclusion, and offers workplace accommodations.

Reg Polysomnographic Technologist -PRN-Mercy Lebanon

Company: Mercy

Location: Lebanon, Missouri

Posted Oct 05, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and hearts, and have been recognized as a top workplace. The Polysomnography Technician position involves providing sleep testing services under supervision, requiring relevant education, licensure, experience, and certifications. Mercy offers great benefits, including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who are compassionate, professional, positive, and advocates for excellent care.

Commerical Underwriter III

Company: PNC

Location: St. Louis, MO

Posted Oct 05, 2024

PNC is seeking a Commercial Underwriter for its Regional Commercial Credit Group, based in St. Louis, Missouri, Kansas City, Kansas, or Chicago, Illinois. The role involves portfolio management of commercial middle market and large corporate finance clients, requiring strong complex credit experience. The position offers independence, exceptional approval authority, and the opportunity to serve as a subject matter expert. PNC values customer focus, risk management, and offers comprehensive benefits. The ideal candidate will have a university degree, 3+ years of relevant experience, and preferred skills in credit decisions, customer needs, decision making, financial analysis, identifying risks, process improvements, and results-orientation.

Division Chief Pediatric Dermatology

Company: SSM Health

Location: Saint Louis, Missouri

Posted Oct 05, 2024

SSM Health Cardinal Glennon Hospital in Saint Louis, Missouri is seeking a full-time Pediatric Dermatologist. The hospital, a Level I Pediatric Trauma Center, serves a diverse population and treats over 50,000 patients annually. The role involves patient care, teaching fellows, residents, and medical students, and performing scholarly duties. SLUCare physicians are guided by a Catholic Jesuit tradition, emphasizing the balance between medical science and compassionate care.

Target Security Specialist

Company: Target

Location: Saint Charles, MD

Posted Oct 04, 2024

Target is offering a job for a Security Specialist with a starting hourly rate of $19.50 USD. The role involves ensuring the safety and security of guests and team members, preventing theft and shortage, and maintaining a safe and secure environment. The job requires a welcoming attitude, effective communication skills, and the ability to work in a fast-paced environment. The company provides training and competitive benefits.

Urologist

Company: Washington University School Of Medicine in St. Louis

Location: St. Louis, Missouri

Posted Oct 04, 2024

Washington University is seeking Urologists for full-time positions in St Louis and Belleville/Shiloh, Illinois. The positions are permanent and offer a competitive salary, opportunities to work with residents, and flexibility in scope of practice. Specialized interests can be accommodated, and robotic surgery with Xi is available at all locations. The successful candidates will join a large physician group with a strong referral base and benefits package.

Pharmacy Technician

Company: CVS Health

Location: Saint Charles, MD

Posted Oct 04, 2024

CVS Health is seeking a dedicated and caring Pharmacy Technician to join their team. The role involves delivering compassionate care to patients, managing pharmacy workstations, and ensuring all medication needs and regulatory compliance standards are met. The company offers a comprehensive training program, opportunities for career growth, and a competitive pay range. The ideal candidate should have attention to detail, strong communication skills, and the ability to work in a fast-paced environment.

Pharmacy Technician

Company: CVS Health

Location: St. Louis, MO

Posted Oct 04, 2024

CVS Health is seeking a dedicated and caring Pharmacy Technician to join their team. The role involves delivering compassionate care to patients, managing pharmacy workstations, and ensuring all medication needs and regulatory compliance standards are met. The company offers a comprehensive training program, opportunities for career growth, and a competitive pay range. The ideal candidate should have attention to detail, strong communication skills, and the ability to work in a fast-paced environment.

Financial Analyst Development Program (FADP) - Minneapolis, MN / Hybrid (2025)

Company: Target

Location: Minneapolis–Saint Paul, MN

Posted Oct 04, 2024

The job posting is for a Financial Planning and Analysis role at Target. The company offers competitive benefits, a collaborative work environment, and opportunities for professional growth. The role involves analyzing financial data, making recommendations, and working with cross-functional teams to drive business decisions.

Physician - Medical Director - MO Poison Center - Clayton MO

Company: SSM Health

Location: Saint Louis, Missouri

Posted Oct 05, 2024

The job posting is for a Medical Director position at the Missouri Poison Center in St. Louis. The role involves clinical supervision, consultation, and development of medical guidelines. The position offers competitive compensation and comprehensive benefits. The city of St. Louis is highlighted for its affordability, diverse neighborhoods, cultural opportunities, and professional sports teams. The job requires medical board certification in toxicology and subspecialty board certification.

SLED Regional Director of Sales (Remote, Minnesota)

Company: Dynatrace

Location: Minneapolis–Saint Paul, MN

Posted Oct 04, 2024

The job description is for a sales team leader position at Dynatrace, a company that provides software for cloud operations and digital experiences. The role requires experience in leading and mentoring sales teams, and the company offers competitive compensation and benefits.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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