Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Graduate Nurse Resident - Neuro Trauma ICU, Full time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Oct 04, 2024

Mercy offers a range of incentives for both new graduate and experienced nurses, including sign-on bonuses, relocation assistance, education assistance, and retirement funds. The NICU team provides critical care for complex traumatic injuries, medical diagnoses, and neuro-surgical emergencies. Qualifications include a registered nursing degree, current RN license, and Basic Life Support certification.

Food Service Worker

Company: Sodexo

Location: St. Louis, MO

Posted Oct 04, 2024

Sodexo offers comprehensive employee benefits packages and detailed job descriptions. As a Food Service Worker, you'll prepare and serve food, maintain cleanliness, and provide excellent customer service. The role is full-time with a pay range of $15.00 per hour. Sodexo values teamwork, adaptability, and a passion for maintaining a healthy and safe environment.

Financial Operations Analyst - HYBRID

Company: Cigna

Location: St. Louis, MO

Posted Oct 04, 2024

The job posting is for a HYBRID role that requires onsite presence in St Louis MO. The Analyst will manage invoicing and cash application for Evernorth Behavioral Health and Military One Source programs. The job requires excellent customer service and communication skills, strong analytical skills, and ability to work under tight deadlines.

Team Leader - Primary Field Supervision

Company: Edward Jones

Location: St. Louis, MO

Posted Oct 04, 2024

Edward Jones is offering a full-time position in the Field Supervision Department. The role involves overseeing a team of Field Supervision Directors, managing workflow, providing training, conducting oversight of FSD work, reviewing client contacts, approving new accounts, and representing the department in various capacities. The ideal candidate should have a Bachelor's degree, Series 7 & 66 licenses, and Series 9 & 10, 24, and insurance licenses. Securities industry experience and excellent communication skills are preferred. The company values its associates and offers a rewards program for long-term career development.

Lead Provider Data Application Engineer

Company: Centene Corporation

Location: St. Louis, MO

Posted Oct 04, 2024

The job posting is for a data modeler and software engineer position at Centene, a diversified national organization. The role involves designing and implementing complex data models and enterprise software solutions, collaborating with technical and non-technical teams, and leading projects focused on data models and application products.

Registered Behavior Tech - Full Time

Company: Mercy

Location: Saint Peters, Missouri

Posted Oct 04, 2024

Mercy Kids Autism Therapy Services is offering a Registered Behavior Technician (RBT) position with a $2,000 sign-on bonus, full-time hours, and comprehensive benefits. The role involves implementing treatment plans for children with autism under the supervision of a BCBA. The position offers opportunities for education, professional growth, and a supportive work environment. Preferred qualifications include a master's degree in ABA, experience with Verbal Behavior and Natural Environment Teaching, and proficiency with online data collection systems.

Product Support Specialist

Company: Thomson Reuters

Location: St. Louis, MO

Posted Oct 04, 2024

The job posting is for a Customer Support Representative role at Thomson Reuters. The role involves providing exceptional product support, resolving customer issues, and ensuring customer satisfaction. Key responsibilities include customer interaction, technical troubleshooting, product knowledge, customer feedback, advocacy, and professional communication. The ideal candidate should have strong communication skills, technical aptitude, patience, and organizational skills. Thomson Reuters offers a comprehensive benefits package, including wellbeing, culture, learning & development, social impact, and purpose-driven work.

Director, Procurement

Company: Chewy

Location: Minneapolis–Saint Paul, MN

Posted Oct 04, 2024

Chewy is recruiting for an Indirect Procurement Category Management Director to lead the Fulfilment Center Sourcing team. The candidate will drive the development and implementation of sourcing strategies, collaborate with executive leadership, and ensure Indirect Procurement is a commercial asset.

Engineer II, QA

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Oct 04, 2024

Thermo Fisher Scientific is seeking a QA Engineer II for their Drug Substance Division in St. Louis, MO. The role involves problem resolution in manufacturing and quality control activities, oversight of pharmaceutical production, and review of GMP documents. The ideal candidate will have a Bachelor's Degree in a science-related field, 3+ years of experience in a GMP environment, and knowledge of industry standards and cGMP regulations. The position requires working 8-hour fixed schedules onsite, with possible weekend work or on-call coverage.

Nurse Practitioner -Home Based Medical Care - St. Louis area, MO

Company: UnitedHealth Group

Location: St. Louis, MO

Posted Oct 04, 2024

Optum is seeking a Nurse Practitioner for its Home-based Medical Care team in Hillsboro, MO. The role involves providing home-based medical care to complex, chronic patients, aiming to keep older adults at home. The Nurse Practitioner will work as a provider member within the HBMC interdisciplinary team, collaborating with PCPs, consultants, and other health professionals to develop and carry out patients' goals of care. The role requires problem-solving, technical skills, customer service, interpersonal skills, oral communication, attendance/punctuality, dependability, and initiative. The Nurse Practitioner must have a Nurse Practitioner accredited program completion, AANP or ANCC certification, current RN and NP licenses, and knowledge of long-term care, community resources, and cost-effective alternatives. Preferred qualifications include clinical experience, knowledge of CPT, ICD-10, HCPC codes, clinical standards of care, and awareness of NCQA requirements, CMS guidelines, Medicaid/Medicare contracts, and benefit systems.

Senior Manager, Pharmaceutical Strategic Business Insights

Company: CVS Health

Location: Saint Paul, MN

Posted Oct 04, 2024

CVS Health is seeking a Senior Manager of Strategic Business Insights to assess and optimize financial performance of initiatives promoting the advancement of CVS Health's long-term strategies across the pharmaceutical landscape. The role involves coordinating cross-functionally, gathering and critically assessing multi-faceted data points, and developing financial modeling to support pharmaceutical new business, partnerships, and net new opportunities. Key responsibilities include contributing to planning and administration of programs, developing a deep understanding of CVS pharmacy internal and external data, incubating new ideas, designing and executing analyses, developing financial forecasts and models, and creating executive materials. Required qualifications include a Bachelor's degree, 7+ years of business analytics, financial modeling, data science or relevant experience, 5+ years in the pharmaceutical industry, proven knowledge of pharmacy economics, strong analytic skills, and advanced proficiency in Microsoft Office Applications. Preferred qualifications include a Masters or advanced degree, experience with data manipulation and SQL, experience building financial models for new business opportunities, strong project management skills, and consulting experience.

Search Engine Optimization Analyst - Performance Marketing

Company: Enterprise Mobility

Location: St. Louis, MO

Posted Oct 04, 2024

Enterprise Mobility, a leading provider of mobility solutions, is seeking a Search Engine Optimization Analyst. The SEO Analyst will develop and implement strategies to maximize traffic and revenue, focusing on technical optimization, business listing management, and performance content optimization. The role offers competitive compensation, comprehensive benefits, and growth potential. Key responsibilities include creating SEO strategies, leveraging content management systems, optimizing local business listings, collaborating with other teams, and staying updated on industry trends.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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