Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Colon & Rectal Surgery Position in MO

Company: Archway Physician Recruitment

Location: Hannibal, Missouri

Posted Sep 30, 2024

Archway Physician Recruitment is offering a Colon & Rectal Surgery position in Hannibal, Missouri. The position is full-time and permanent with competitive base compensation and additional earning potential. Benefits include a $50,000 relocation loan, $2,000 monthly residency stipend, up to $100,000 in student loan repayment, and a $10,000 moving stipend. The new surgery suites are equipped with a robot and Allscripts PRO EMR. Hannibal, located on the Mississippi River, is a family-focused community with strong school systems, numerous sports leagues, and an active arts council. It's known for being the boyhood home of Mark Twain and has a thriving artist community due to its central location and affordable real estate.

General Surgeon Is Needed for Locum Tenens Help in MO CPH# JOB-2986973

Company: CompHealth

Location: Memphis, Missouri

Posted Sep 30, 2024

CompHealth offers a wide range of locum tenens assignments in General Surgery, with opportunities tailored to individual needs and career phases. They provide expert guidance, negotiate better pay, arrange housing and travel, and simplify credentialing. The company has been in business since 1979 and is known for its excellent customer service.

General Surgery opening in southeast Missouri

Company: Archway Physician Recruitment

Location: Sikeston, Missouri

Posted Sep 30, 2024

A full-time, permanent General Surgeon position is available in Sikeston, MO, a town in southeast Missouri. The role involves mostly bread and butter general surgery, with the possibility of dialysis access work. The compensation package includes competitive salary, standard hospital benefits, CME allowance, and two weeks paid vacation annually. Sikeston offers affordable accommodations, unique dining and shopping opportunities, festivals, historical and cultural events, and southern hospitality.

GS-Upstate Missouri-We have a strategic relationship with University of Missouri

Company: Community Health Systems

Location: Kirksville, Missouri 63501

Posted Sep 30, 2024

Northeast Regional Medical Center in Kirksville, Missouri, is a 93-bed facility with over 75 physicians on staff. It serves as the teaching hospital for the founding school of Osteopathic Medicine and has formed a strategic relationship with the University of Missouri-Columbia. The hospital is actively recruiting a General Surgeon and offers a competitive recruitment package. Kirksville offers a moderate-sized high school, above-average education system, and a variety of community amenities including wineries, museums, parks, and recreational activities. The city is known for its three major educational institutions and is the birthplace of Osteopathic Medicine. Northeast Regional Medical Center has been named one of America's 50 Best Hospitals.

General Surgeon opening in Vermont

Company: Archway Physician Recruitment

Location: Saint Johnsbury, Vermont

Posted Sep 30, 2024

A General Surgeon position is available in St. Johnsbury, Vermont. The service area covers 40,000 people, with Montreal being 150 miles north. The role is full-time, day shift, with shared call duties (1:3). The surgeon will perform various procedures including skin lesion excisions, gall bladder removal, hernia repair, advanced laparoscopy, endoscopy/colonoscopy, and breast biopsies. Benefits include a competitive salary, loan repayment, relocation assistance, 401k with company match, generous paid time off, continuing medical education opportunities, complimentary gym membership, and comprehensive health/dental/vision insurance. The hospital is located in Vermont's Northeast Kingdom, known for its rural charm, unspoiled beauty, and four-season recreational activities.

Temp to Perm Position in MO for Pediatric General Surgeon CPH# JOB-2932355

Company: CompHealth

Location: Missouri

Posted Sep 30, 2024

CompHealth offers a wide range of locum tenens assignments, including pediatric surgery in Missouri. They provide expert guidance, negotiate better pay, arrange housing and travel, and offer comprehensive malpractice coverage. Their specialized recruiters handle every detail, ensuring a tailored experience for healthcare providers.

A Facility in Missouri Needs a Locum Tenens General Surgeon CPH# JOB-2981712

Company: CompHealth

Location: Missouri

Posted Sep 30, 2024

CompHealth, a leading healthcare staffing company, offers comprehensive support to general surgery locum tenens in Missouri. They provide a dedicated recruiter, specialized teams for housing, travel, credentialing, and licensing, and negotiate better pay with weekly deposits. They also offer malpractice coverage, an online portal for assignment details, and simplify the credentialing process.

Loan Forgiveness with a Cutting-Edge Practice

Company: Curare Physician Recruiting

Location: Saint Paul, Minnesota 55101

Posted Sep 30, 2024

An established multi-specialty practice with four experienced general surgeons is seeking another BC/BE general surgeon to join their group. The practice includes endoscopy and colonoscopy, but no C-sections. They provide surgical services and admissions at the Regional Medical Center, which supports six surrounding community clinics. The practice offers a competitive annual salary, quality bonus production incentives, loan forgiveness, and a signing bonus. They also provide a retirement plan, vacation and CME, malpractice coverage, CME allowance, and a relocation package. The Medical Center features 6 ICU beds, 10 Telemetry Step Down beds, 4 OB beds, 2 Pediatrics beds, and 16 Med Surg beds. The Curare Group, a physician recruitment industry leader for 25 years, is assisting with the job search.

General Surgery opening in Missouri

Company: Archway Physician Recruitment

Location: West Plains, Missouri

Posted Sep 30, 2024

Ozarks Healthcare in West Plains, Missouri is seeking a compassionate BE/BC general surgeon for a full-time, permanent position. The successful candidate will join a team of 2 other general surgeons and benefit from a team-oriented work environment. The hospital is expanding with a new Women's Center and a 100,000 square foot medical office building. The position offers a competitive salary, sign-on bonus, relocation reimbursement, and educational stipend. West Plains is a family-oriented community in the beautiful Ozark mountains, offering abundant outdoor recreational activities and excellent educational opportunities.

Acute Care General Surgeon in Birmingham, AL

Company: TeamHealth

Location: 810 Saint Vincents DrBirmingham, Alabama 35205

Posted Sep 30, 2024

TeamHealth is seeking a board-certified general surgeon to join their acute-care general surgery program at Ascension St. Vincent's Birmingham. The position offers flexible scheduling, hospital coverage for acute general surgery ED patients and hospital consults, post-operative/post-hospital clinic follow-up, variety of general surgical operative procedures, minimal trauma with a variety of cases, and access to TeamHealth's wellness program, professional development tools, and nation-wide network of general surgeons. The hospital is Alabama's leader in Robotic Surgery and includes a state-of-the-art Cancer Center, Neuro Spine Center, Orthopedics Center, Women’s and Children’s service and Cardiac Care.

General Surgeon Needed Near Saint Louis

Company: Curare Physician Recruiting

Location: St. Louis, Missouri 63101

Posted Sep 30, 2024

A General Surgeon position is available in a busy hospital in Illinois, offering a great opportunity to join an established practice near St. Louis, Missouri. The hospital employee position includes a 1:2 call ratio, a salary of $450-475K, and various incentives such as a signing bonus, residency/fellowship stipend, relocation bonus, CME, and up to 4 weeks of PTO. The hospital uses EPIC for EMR and offers daVinci for those interested. Curare Physician Recruiting is facilitating the recruitment process.

General Surgeon Opportunity at Poplar Bluff Regional Medical Center

Company: Community Health Systems

Location: Poplar Bluff, Missouri 63901

Posted Sep 30, 2024

Poplar Bluff Regional Medical Center is recruiting a Board Eligible or Certified General Surgeon. The position offers a competitive salary with productivity incentives, comprehensive benefits, a commencement bonus, and student loan repayment assistance. The surgeon will have an inpatient/outpatient role, access to advanced technology like the DaVinci robot, and work in a growing practice. Poplar Bluff, Missouri offers a quality of life with a low cost of living, outdoor activities, a golf course, and a robust public school system.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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