Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Health Science Specialist

Company: Department of Veterans Affairs - Veterans Health Administration

Location: Saint Louis, Missouri Saint Louis, Missouri

Posted Sep 30, 2024

The position is vital within the Office of Research and Development ORD and the facilities where research programs are conducted.

Rheumatology opening near Springfield, MO

Company: Archway Physician Recruitment

Location: Bolivar, Missouri

Posted Sep 30, 2024

A Rheumatology position is available in Bolivar, MO, a town 25 miles from Springfield. The position is full-time, permanent, and hospital-employed. It's part of a busy, well-established Rheumatology group, necessitated by growth and an upcoming retirement. No call is required. The office suite is in a modern medical center with an adjacent infusion center, outpatient imaging, lab, and therapy services. Benefits include a competitive salary, sign-on bonus, retirement and profit-sharing, insurance, paid time off, resident/fellowship stipend, CME allowance, loan assistance, and relocation assistance. The hospital is highly rated, recognized for its patient safety and quality of care. Bolivar, the location, offers a National Blue Ribbon school system, low crime rates, and amenities like a golf club, trailhead, and university.

PLANS AND OPERATIONS SPECIALIST (TITLE 5)

Company: Department of the Army - Army National Guard Units

Location: Saint Augustine, Florida Saint Augustine, Florida

Posted Sep 30, 2024

This is a National Guard position for a Plans and Operations Specialist. It is a Title 5 excepted service position.

Cardiothoracic Surgery opening in SW Missouri

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Sep 30, 2024

A full-time, permanent position for a BE/BC Cardiothoracic Surgeon is available in Joplin, MO. The position offers a generous guarantee contract, excellent benefits, and a supportive professional environment. Joplin, a city of 50,000 with a low cost of living, provides an excellent quality of life with numerous recreational activities and educational options. The city is also a growing medical hub with Kansas City University-Joplin's medical school.

Nursing Assistant-Mental Health (51 West)

Company: Department of Veterans Affairs - Veterans Health Administration

Location: Jefferson Barracks, Missouri Jefferson Barracks, Missouri

Posted Sep 30, 2024

The St Louis VA Medical Center is recruiting Fulltime permanent Nursing Assistants for our Mental Health department.

Heavy Mobile Equipment Repairer

Company: Department of the Army - U.S. Army Reserve Command

Location: Weldon Spring, Missouri Weldon Spring, Missouri

Posted Sep 30, 2024

This is a Military Technician position with the 88th Readiness Division Area Maintenance Support Activity 159th located in Weldon Springs Missouri. The position requires an active membership as a Soldier in the Army Reserve.

Cardiovascular Surgeon opening in SW Missouri

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Sep 30, 2024

A Cardiovascular Surgeon position is available in Joplin, Missouri. The job is full-time and permanent, offering a generous guarantee contract, excellent benefits, and a supportive work environment. Joplin, the fourth-largest metropolitan area in the state, offers a low cost of living, diverse medical hub, and numerous recreational activities. The location provides easy access to three CV ORs, four Cath Labs, and a dedicated Anesthesia team.

Arkansas Breast Surgery Opportunity Available

Company: Curare Physician Recruiting

Location: Springfield, Missouri 65801

Posted Sep 30, 2024

A fellowship-trained Breast Surgeon is sought to join a well-established single-specialty group in Springfield, Missouri. The breast center offers advanced imaging, including digital and 3D, and has a DaVinci Robot onsite. The location is near the Ozarks, with a population of over half a million and direct flights to major metros. The position is a hospital employee with outpatient work and minimal call. Competitive salary, production incentives, loan forgiveness, signing bonus, relocation bonus, CME time and money, and comprehensive benefits are offered. The ideal candidate is fellowship-trained in Breast Surgical Oncology.

Rheumatology opening in SW Missouri

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Sep 30, 2024

A Rheumatology position is available in Joplin, Missouri. The practice is outpatient and involves general Rheumatology with referrals from primary care. The clinic offers ancillary support and collaboration with other specialists. The location in Joplin provides a high quality of life with a low cost of living, diverse activities, and excellent educational options. The company, Archway Physician Recruitment, is a national contingency placement firm.

Pediatric Radiologist Is Wanted for Locums Coverage in Missouri CPH# JOB-2958703

Company: CompHealth

Location: St. Louis, Missouri

Posted Sep 30, 2024

CompHealth offers comprehensive locums support for Pediatric Radiology positions, including job search, credentialing, housing, travel arrangements, and better pay. They provide weekly deposits, malpractice coverage, and a user-friendly online portal for assignment details. Their specialized recruiters handle all details, allowing healthcare providers to focus on patient care.

Radiation Oncologist Is Wanted for Locums Help in Missouri CPH# JOB-2984684

Company: CompHealth

Location: Missouri

Posted Sep 30, 2024

CompHealth is offering a Radiation Oncology position in Missouri. The job involves treating adult patients, handling new consults and follow-ups, and using IMRT, IGRT, SRS & SBRT. CompHealth will manage housing, credentialing, and provide better pay with weekly deposits. They also offer malpractice coverage and a user-friendly online portal for assignment details.

New Graduates Welcome and Visa Sponsorship Available

Company: Curare Physician Recruiting

Location: Springfield, Missouri 65801

Posted Sep 30, 2024

A busy client in Missouri is hiring a General Surgeon, offering a competitive compensation package, relocation assistance, and a signing bonus. The location, known as the 'Heart of the Ozarks', offers outdoor activities. The clinic is moving into a new 100,000 square foot building. The position is open due to increased volume. The hospital has 2 full-time general surgeons and 1 private practice general surgeon. The clinic operates Monday - Friday, 8 a.m. - 5 p.m. with MD Anesthesia coverage. Additional benefits include student loan support, CME stipends, and a 403B matching plan.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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