Tech Jobs in San Diego, CA

1,131,473 open positions · Updated daily

San Diego's tech scene blends a sunny coastal vibe with a robust research ecosystem. The city hosts world‑class life‑science labs, defense R&D facilities, and a growing startup cluster that thrives on collaboration with nearby universities like UC San Diego and San Diego State. Recent data shows a 12% year‑over‑year increase in tech hires, driven by demand for AI, cybersecurity, and marine technology.

Key industries include biotech and pharmaceuticals—home to Illumina, Pfizer, and Gilead—, defense contractors such as Lockheed Martin and Northrop Grumman, and software & cloud services firms like Qualcomm, Amazon Web Services, and local SaaS startups in Mission Valley. The city’s proximity to the U.S. Naval Base and NASA’s JPL also fuels niche opportunities in aerospace and data analytics.

San Diego’s median rent for a two‑bedroom apartment tops $2,800, and the overall cost‑of‑living index sits 26% above the national average. Because housing and transportation costs are high, knowing the exact salary range before you apply is crucial. Our transparent listings let candidates compare offers, negotiate confidently, and evaluate whether a role meets their financial goals.

Senior AI/Python Engineer

Company: Fuel Cycle

Location: Los Angeles, CA

Posted Aug 28, 2025

Strong communication skills, with the ability to explain complex technical concepts to non-technical stakeholders. 15 vacation days and 7 sick days per year.

Security Specialist - Veterans Preferred

Company: Gavin de Becker & Associates

Location: Los Angeles, CA

Posted Aug 28, 2025

PLT includes 500 hours of training, mentoring, instructing, and certification + 4 additional advanced executive protection/leadership training academies.

CDL-A Truck Drivers - Home Daily - Earn Up to $120,000/Year + Benefits

Company: Sysco

Location: Walnut, CA

Posted Aug 28, 2025

License to drive - valid Class A Commercial Driver License (CDL) with a clean driving record. Sysco has immediate job openings for dependable CDL-A Delivery…

Planning & Logistics Project Lead

Company: ASML

Location: San Diego, CA

Posted Aug 28, 2025

Lead and coordinate P&L teams towards future state of SF. Bachelor degree in supply chain/logistics, industrial engineering, or business administration or…

Staff Accountant - Income Auditor

Company: CASA DEL MAR

Location: Santa Monica, CA

Posted Aug 28, 2025

Answer and assist with telephone inquiries in an efficient, courteous and professional manner, using correct telephone etiquette.

Clinical Pharmacy Specialist

Company: El Camino Health

Location: Mountain View, CA

Posted Aug 28, 2025

Valid California state pharmacist license with no disciplinary action(s) against the licensee that prohibits the licensee from practicing pharmacy.

Client Services Specialist

Company: L. K. Jordan & Associates

Location: San Antonio, TX

Posted Aug 28, 2025

Reliable transportation and a valid driver's license. LK Jordan has 3 IMMEDIATE openings for _*Client Services Specialists*_ needed to assist in taking of…

Senior Python/AI Engineer

Company: Fuel Cycle

Location: Los Angeles, CA

Posted Aug 28, 2025

Strong communication skills, with the ability to explain complex technical concepts to non-technical stakeholders. 15 vacation days and 7 sick days per year.

Pastry Chef and Baker

Company: Restaurant

Location: Burbank, CA

Posted Aug 28, 2025

Ability to lead a team while ensuring consistency and quality. Some computer knowledge for managing production.

Accounting Manager

Company: Vagaro

Location: Pleasanton, CA

Posted Aug 28, 2025

Provide technical accounting guidance for complex GL transactions and accruals. Lead cash and inventory accounting, including daily cash positioning and bank…

Plastic Surgery RN

Company: Restore SD Plastic Surgery

Location: San Diego, CA

Posted Aug 28, 2025

Active Registered Nurse (RN) license in California. Communicate with patients and their families to address concerns, provide updates, and answer questions…

Seasonal Sales Associate

Company: Nespresso

Location: Palo Alto, CA

Posted Aug 28, 2025

As the welcoming face of our retail boutique, you will greet customers, offer complimentary coffee tastings, help with boutique operations and provide an…

Frequently Asked Questions

What types of tech jobs are available in San Diego?
San Diego offers a spectrum of tech roles: software engineers (frontend, backend, full‑stack), data scientists, machine learning engineers, cybersecurity analysts, bioinformatics specialists, embedded systems developers, product managers, UX/UI designers, and DevOps engineers. Companies like Qualcomm, Illumina, Pfizer, and local SaaS firms hire across these disciplines.
Is remote work common for tech positions in San Diego?
About 60% of tech roles in San Diego allow remote or hybrid arrangements. Major employers such as Amazon, Google, and Northrop Grumman offer flexible schedules, while many startups maintain on‑site teams to foster collaboration. Remote candidates should verify the company’s policy during the interview process.
Who are the major tech employers in San Diego?
Key employers include Qualcomm, Illumina, Pfizer, Gilead, Lockheed Martin, Northrop Grumman, Amazon Web Services, Google, NASA’s Jet Propulsion Laboratory, the University of California San Diego, and a growing number of SaaS startups in Mission Valley, La Jolla, and Downtown.
What are the salary expectations for tech roles in San Diego?
Median salaries vary by role: software engineers earn between $90k–$140k, data scientists $100k–$150k, bioinformatics professionals $110k–$160k, and cybersecurity analysts $95k–$140k. Benefits and equity packages often supplement base pay, especially in biotech and defense sectors.
How can I prepare for relocating to San Diego for tech work?
Research neighborhoods: Mission Valley and La Jolla offer high‑tech hubs with easy commutes; Downtown offers vibrant nightlife; and Point Loma provides a quieter coastal feel. Compare rental costs, school districts, and commute times. Attend local meetups, such as the San Diego DevOps Meetup or the SD Tech Community, to network. Utilize our salary transparency data to negotiate offers that align with your cost of living.

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