Tech Jobs in San Mateo, CA

1,130,167 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Associate Data Scientist, Taste Ingredient Discovery - San Diego, CA

Company: dsm-firmenich

Location: San Diego, CA

Posted Oct 01, 2025

3-5 years of additional academic (e.g. PhD studies) or industry work experience in ML/AI and bioinformatics applied to ingredients, or small molecule discovery,…

IT Compliance Analyst

Company: Skechers USA, Inc.

Location: Manhattan Beach, CA

Posted Oct 01, 2025

Bachelor’s degree in information technology, Computer Science, or a related field. Act as point of contact for audits, facilitate written IT responses to audit…

Registered Nurse (RN) Emergency

Company: Adventist Health

Location: Glendale, CA

Posted Oct 01, 2025

Registered Nurse (RN) licensure in the state of practice: Required. Cardiopulmonary Resuscitation (CPR) or Basic Life Support (BLS OR HS-BLS OR RQIBLS)…

STIIIZY Dispensary Sales Associate

Company: Stiiizy

Location: Los Angeles, CA

Posted Oct 01, 2025

Are you interested in working for the world's largest cannabis market with a footprint that covers the entire breadth of the state of California?

Substitute Teacher - Special Education, Bilingual

Company: Swing Education

Location: Milpitas, CA

Posted Oct 01, 2025

Daily rates from $190 to $220, depending on school, location, and your certification. *Total schedule flexibility:* Get teaching requests in real time and…

Software Engineering Manager 1

Company: Northrop Grumman

Location: Los Angeles, CA

Posted Oct 01, 2025

Responsible for technical guidance and oversight in developing technical and cost proposals. The technical role will focus on algorithmic application…

Substitute Teacher

Company: Swing Education

Location: El Cajon, CA

Posted Oct 01, 2025

Daily rates from $180 to $280 depending on school, location, and your certification. We support substitute teachers with meaningful perks, real-time tools, and…

Infrastructure Engineer

Company: Acara Solutions

Location: San Antonio, TX

Posted Oct 01, 2025

Do you have infrastructure/analyst experience in a field that supports and provides technical and analytical solutions? Here's what you'd do:

Substitute Teacher

Company: Swing Education

Location: San Diego, CA

Posted Oct 01, 2025

Daily rates from $180 to $280 depending on school, location, and your certification. We support substitute teachers with meaningful perks, real-time tools, and…

Machine Learning Engineer / Wireless Systems / Hybrid Los Angeles

Company: Motion Recruitment

Location: Los Angeles, CA

Posted Oct 01, 2025

M.S. or Ph.D. in Electrical Engineering, Computer Science, or related field. Background in Radio Frequency data analysis or spectrum sensing.

Business Data Analyst

Company: Elwood Professional

Location: Carson, CA

Posted Oct 01, 2025

This role is highly cross-functional, where you will own the data backbone for various projects with a primary focus on project budgeting.

Hospital Manager of Marketing and Communications

Company: Clinical Management Consultants

Location: Beverly Hills, CA

Posted Oct 01, 2025

Reporting into the Director of Communications in the Marketing and Communications department, the Marketing and Communication Manager will develop a strategic…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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