Tech Jobs in San Mateo, CA

1,130,266 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Senior AI/Python Engineer

Company: Fuel Cycle

Location: Los Angeles, CA

Posted Aug 28, 2025

Strong communication skills, with the ability to explain complex technical concepts to non-technical stakeholders. 15 vacation days and 7 sick days per year.

Security Specialist - Veterans Preferred

Company: Gavin de Becker & Associates

Location: Los Angeles, CA

Posted Aug 28, 2025

PLT includes 500 hours of training, mentoring, instructing, and certification + 4 additional advanced executive protection/leadership training academies.

CDL-A Truck Drivers - Home Daily - Earn Up to $120,000/Year + Benefits

Company: Sysco

Location: Walnut, CA

Posted Aug 28, 2025

License to drive - valid Class A Commercial Driver License (CDL) with a clean driving record. Sysco has immediate job openings for dependable CDL-A Delivery…

Planning & Logistics Project Lead

Company: ASML

Location: San Diego, CA

Posted Aug 28, 2025

Lead and coordinate P&L teams towards future state of SF. Bachelor degree in supply chain/logistics, industrial engineering, or business administration or…

Staff Accountant - Income Auditor

Company: CASA DEL MAR

Location: Santa Monica, CA

Posted Aug 28, 2025

Answer and assist with telephone inquiries in an efficient, courteous and professional manner, using correct telephone etiquette.

Clinical Pharmacy Specialist

Company: El Camino Health

Location: Mountain View, CA

Posted Aug 28, 2025

Valid California state pharmacist license with no disciplinary action(s) against the licensee that prohibits the licensee from practicing pharmacy.

Client Services Specialist

Company: L. K. Jordan & Associates

Location: San Antonio, TX

Posted Aug 28, 2025

Reliable transportation and a valid driver's license. LK Jordan has 3 IMMEDIATE openings for _*Client Services Specialists*_ needed to assist in taking of…

Senior Python/AI Engineer

Company: Fuel Cycle

Location: Los Angeles, CA

Posted Aug 28, 2025

Strong communication skills, with the ability to explain complex technical concepts to non-technical stakeholders. 15 vacation days and 7 sick days per year.

Pastry Chef and Baker

Company: Restaurant

Location: Burbank, CA

Posted Aug 28, 2025

Ability to lead a team while ensuring consistency and quality. Some computer knowledge for managing production.

Accounting Manager

Company: Vagaro

Location: Pleasanton, CA

Posted Aug 28, 2025

Provide technical accounting guidance for complex GL transactions and accruals. Lead cash and inventory accounting, including daily cash positioning and bank…

Plastic Surgery RN

Company: Restore SD Plastic Surgery

Location: San Diego, CA

Posted Aug 28, 2025

Active Registered Nurse (RN) license in California. Communicate with patients and their families to address concerns, provide updates, and answer questions…

Seasonal Sales Associate

Company: Nespresso

Location: Palo Alto, CA

Posted Aug 28, 2025

As the welcoming face of our retail boutique, you will greet customers, offer complimentary coffee tastings, help with boutique operations and provide an…

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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