Tech Jobs in San Mateo, CA

1,130,453 open positions · Updated daily

San Mateo sits on the edge of Silicon Valley, offering easy access to BART and a walkable downtown with cafes, parks, and coworking hubs. The city hosts a vibrant mix of startups, Fortune 500 tech firms, and research labs, drawing talent from Stanford, UC Berkeley, and major tech schools nearby.

Tech roles range from cloud infrastructure and AI research to fintech product management and cybersecurity architecture. Companies such as Salesforce, Adobe, Twitter, and Uber maintain regional offices, while emerging startups like Scribe and Sinequa build products in healthtech and search AI. Biotech firms in nearby Redwood City and biotech incubators in San Mateo’s Hillsdale area further diversify the ecosystem.

Living costs are high: median home price exceeds $1.4 million and the average rent for a 1‑bedroom apartment is around $3,200/month. Salary transparency lets candidates compare offers, negotiate effectively, and align compensation with the cost of living and local market rates.

Travel Contract Inpatient Staff Pharmacist Day Shift Northern, CA

Company: RPh on the Go

Location: Santa Clara, CA

Posted Aug 22, 2025

Doctor of Pharmacy (PharmD) degree, active Pharmacist license, and minimum 1+ years Pharmacist experience required. Oversee technician accuracy and workflow.

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: Long Beach, CA

Posted Aug 22, 2025

Top drivers *earn up to $127,000 per year\**. *No Flatbed experience required* for experienced OTR drivers – Get trained for Flatbed during orientation.

Transitional Kindergarten Teacher

Company: The Roman Catholic Archdiocese of Los Angeles (LA Catholics)

Location: Los Angeles, CA

Posted Aug 22, 2025

This position is for a teacher who can teach all core subjects in Catholic educational environment. The rate of pay offered to the selected candidate is based…

Staff Nurse

Company: University Health

Location: San Antonio, TX

Posted Aug 22, 2025

Current RN license from the Texas Board of Nursing. Comprehensive benefits package including pet insurance. RN Student Loan Repayment Program.

Auxiliary Security Officer

Company: Marksman Security

Location: Culver City, CA

Posted Aug 22, 2025

Provide excellent customer service which could include giving directions, opening doors and greeting employees, visitors and contractors in a proper manner.

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: San Diego, CA

Posted Aug 22, 2025

Central Oregon Trucking Company is hiring experienced CDL A truck drivers seeking industry-leading pay and benefits and ready to haul flatbed freight with the…

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: Fremont, CA

Posted Aug 22, 2025

Top drivers *earn up to $127,000 per year\**. *No Flatbed experience required* for experienced OTR drivers – Get trained for Flatbed during orientation.

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: Santa Monica, CA

Posted Aug 22, 2025

Top drivers *earn up to $127,000 per year\**. *No Flatbed experience required* for experienced OTR drivers – Get trained for Flatbed during orientation.

Manager Pharmacy Business - Home Infusion

Company: Providence

Location: Burbank, CA

Posted Aug 22, 2025

This includes oversight and accountability for: front end revenue cycle including insurance benefits investigation, prior authorizations, delivery ticket…

Clinical RN - Emergency - Grossmont Hospital - Night - FT - May be eligible for $5k relocation assistance

Company: SHARP HEALTHCARE

Location: La Mesa, CA

Posted Aug 22, 2025

Independently performs the nursing process through individualized assessment, planning, implementation and evaluation of safe, therapeutic, efficient care for…

CDL A OTR Truck Driver - $1250 orientation pay

Company: Central Oregon Truck Company

Location: Los Angeles, CA

Posted Aug 22, 2025

Top drivers *earn up to $127,000 per year\**. *No Flatbed experience required* for experienced OTR drivers – Get trained for Flatbed during orientation.

Senior Lead Refrigeration Technician

Company: R.W. Zant

Location: Los Angeles, CA

Posted Aug 22, 2025

Respond to and manage emergency service calls; demonstrate flexibility with occasional after-hours availability. Schedule: Full-Time | On-Site.

Frequently Asked Questions

What types of tech jobs are available in San Mateo, CA?
San Mateo hosts roles in software engineering (full‑stack, mobile, data), product management, UX/UI design, DevOps, AI/ML research, cybersecurity, cloud architecture, fintech development, healthtech R&D, and biotech software support.
Are tech jobs in San Mateo remote, on‑site, or hybrid?
The majority (≈65%) of openings require on‑site presence in Downtown or Hillsdale, but 30% offer hybrid schedules and 5% are fully remote, reflecting the city’s mix of legacy firms and agile startups.
Who are the major employers in San Mateo?
Key employers include Salesforce, Adobe, Twitter, Uber, Lyft, Palantir, and regional offices of Google, LinkedIn, and Meta. Startups such as Scribe, Sinequa, and local biotech incubator companies also dominate hiring.
What are the salary expectations for tech roles in San Mateo?
Base salaries for software engineers begin at $110,000 and average $150,000–$170,000 for senior roles; product managers average $135,000–$160,000; data scientists average $145,000; cybersecurity roles average $140,000–$165,000. Total compensation often includes bonuses, RSUs, and benefits.
What should I know before relocating to San Mateo for tech work?
Plan for high housing costs—factor in $3,200 monthly rent or $1.4 million median home price. Evaluate commute options: BART, Caltrain, and local bus routes serve downtown. Research local coworking spaces, networking events, and community groups like San Mateo Tech Meetups to ease transition.

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