Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Physician Assistant (PA-C)

Company:

Location: Kansas City, MO

Posted Jan 23, 2025

Entry Level Outside Sales Representative

Company:

Location: Westboro, MO

Posted Jan 23, 2025

Commission Sales Associate - Furniture

Company:

Location: Springfield, MO

Posted Jan 23, 2025

Ashley HomeStore is currently hiring Retail Sales Associates. The role involves selling furniture, mattresses, and home decor through excellent customer service. No prior sales experience is necessary, but it's a plus. Top writers can earn over $100,000. The compensation is based on written sales commission with a guaranteed hourly wage, potentially earning up to $100,000 or more. Benefits include generous paid time off, medical, dental, vision, and retirement benefits, and employee purchase discounts. Key responsibilities include assisting customers, demonstrating closing skills, and maintaining a clean working environment. Required skills include basic computer skills, strong communication, and organizational skills.

Territory Sales Manager

Company:

Location: St. Louis, MO / Remote

Posted Jan 23, 2025

Uline, a leading distributor of shipping, industrial, and packaging materials, is seeking a Territory Sales Manager. The role involves building and maintaining strong customer relationships, managing and growing existing accounts, and bringing in new business. Uline offers comprehensive training, mentorship, and a range of benefits including complete insurance coverage, 401(k) with employer match, paid holidays, and generous paid time off. The position allows for work-life balance and opportunities for career growth and transition to new markets.

Nurse Manager-$10,000 Sign On Bonus

Company:

Location: Chesterfield, MO

Posted Jan 23, 2025

Bioenvironmental Engineer

Company:

Location: St. Louis, MO

Posted Jan 23, 2025

Roofing Sales Immediately Hiring

Company:

Location: St. Charles, IL

Posted Jan 23, 2025

Bioenvironmental Engineer

Company:

Location: St. Augustine, FL

Posted Jan 23, 2025

The text discusses the Air Force's commitment to environmental safety, emphasizing the role of Bioenvironmental Engineers in identifying and mitigating potential hazards. These specialists, through engineering and scientific principles, ensure the health and safety of Airmen and their families worldwide. The text also outlines the requirements for joining the Air Force, including a Bachelor of Science in engineering from an ABET-accredited institution, completion of specific courses, and age restrictions.

RETAIL SALES ASSOCIATE

Company:

Location: Springfield, MO

Posted Jan 23, 2025

Multi-Site (Flex) Security Officers

Company:

Location: Fenton, MO

Posted Jan 23, 2025

Cyber Systems Operations

Company:

Location: Sikeston, MO

Posted Jan 23, 2025

The Air Force emphasizes the importance of securing advanced computer and software systems, which is the role of Cyber Systems Operations specialists. These experts design, install, and maintain systems to ensure optimal operation and security. They enhance capabilities and provide secure systems. To join the Air Force, one must meet various requirements including educational background, health standards, and ASVAB score requirements. High school seniors can start their application during their junior year.

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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