Tech Jobs in St. Louis, MO

61,353 open positions · Updated daily

St. Louis is becoming a tech hub thanks to a blend of healthcare innovation, a strong manufacturing base, and a growing fintech scene. With 14,708 tech openings, the city offers a mix of high‑growth startups and established firms, all powered by a talent pool fed by universities such as Saint Louis University and Washington University.

Key sectors driving the market include healthtech—home to life‑science giants like BJC HealthCare and Eli Lilly—financial technology, logistics software, and data analytics. Companies like Enterprise Holdings, Vontel, and the City of St. Louis use cutting‑edge platforms to streamline operations, while startups in the Central West End and Midtown districts are hiring full‑stack developers, AI/ML engineers, and cybersecurity specialists.

While the cost of living in St. Louis remains 15% below the national average, median rent for a one‑bedroom apartment in Midtown is around $1,200 and the median home price sits near $225,000. Transparent salary listings let candidates evaluate whether a role’s pay aligns with local living expenses—ensuring you can afford the lifestyle you want without hidden surprises.

Department Supervisor

Company: H&M

Location: Independence, MO

Posted Jan 23, 2025

Pharmacy Technician / Pharm Tech Apprenticeship

Company: Walgreens

Location: O'Fallon, MO

Posted Jan 23, 2025

Walgreens is transforming its pharmacy technician roles into a more patient-centric environment. As a Walgreens Pharmacy Technician or Apprentice, you'll interact with customers, develop strong patient relationships, and have access to the latest technology to grow your career. Walgreens offers an 'earn while you learn' Pharmacy Technician Training Program, recognized by ASHP and the Department of Labor, which guides you towards becoming a PTCB Certified Pharmacy Technician. The role involves assisting pharmacists, using pharmacy systems, maintaining customer service, and participating in inventory management. Fluency in English, good math and computer skills, and preferably prior retail or Walgreens experience are required. PTCB certification is preferred but not mandatory. The role offers training, personal development opportunities, and potential for eight college credit hours through the Walgreens pharmacy technician apprenticeship program.

Certified Pharmacy Technician

Company: Walgreens

Location: St. Cloud, MN

Posted Jan 23, 2025

The role involves assisting the pharmacist in the practice of pharmacy, adhering to state, federal, and company regulations. Duties include using pharmacy systems for patient and drug information, processing prescriptions, and maintaining pharmacy systems. The individual will also engage customers, resolve issues, and ensure a positive experience. They will perform various tasks under the supervision of the pharmacist, staff pharmacist, and store manager, including filling prescriptions, maintaining work flow, and handling cash. The role also involves inventory management, clinical services, and maintaining good relationships with the local medical community. PTCB certification is preferred but not required, and the individual must be fluent in English and willing to work flexible hours.

Pharmacy Customer Service Associate

Company: Walgreens

Location: St. Augustine, FL

Posted Jan 23, 2025

Store Manager Unassigned

Company: Walgreens

Location: Kansas City, MO

Posted Jan 23, 2025

Pharmacy Customer Service Associate

Company: Walgreens

Location: Maryland Heights, MO

Posted Jan 23, 2025

Lead BizOps Engineer

Company: Mastercard

Location: O'Fallon, MO

Posted Jan 23, 2025

Mastercard is seeking a Lead Reliability Engineer for its Business Operations team. The role involves ensuring platform stability, fostering developer ownership, and empowering them to build resilient products. The engineer will manage Site Reliability Engineers, define strategies for application performance monitoring, and focus on continuous optimizations. They will also be responsible for incident response, risk management, and aligning operational needs with product and customer priorities. The ideal candidate should have a Bachelor's degree in computer science or a related field, extensive experience in Big Data technologies, AWS or other cloud platforms, and industry-standard CI/CD tools. They should also have strong coding abilities, a systematic problem-solving approach, and experience in designing and implementing data governance processes.

Warehouse Order Selector

Company: Sysco

Location: St. Cloud, MN

Posted Jan 23, 2025

Sales Representative - Bilingual (Mandarin)

Company: Sysco

Location: St. Louis, MO

Posted Jan 23, 2025

Sysco St. Louis, LLC is seeking a full-time Sales Professional, Restaurant Manager, Culinary Manager, or Chef for an outside sales position in North St. Louis, MO. The role involves promoting the company's products and services, building relationships with new and existing accounts, and achieving sales and profit goals. Key responsibilities include developing new business, penetrating existing accounts, and minimizing lost business. The ideal candidate should have a Bachelor's degree in Business, Sales, Marketing, Hospitality, Culinary Arts, or related discipline, or equivalent experience. Preferred qualifications include bilingualism, restaurant management, foodservice outside sales, and chef experience. The position offers a competitive base salary, bonus, promotional incentives, car allowance, career pathing opportunities, and a robust benefits package.

Airborne Cryptologic Language Analyst

Company:

Location: St. Charles, IL

Posted Jan 23, 2025

Airborne Cryptologic Language Analysts are crucial in translating intelligence communications during flight, providing threat warnings and actionable intelligence. They require fluency in foreign languages, successful completion of various courses, and meet specific physical and health standards. High school seniors or diploma holders can apply, with non-graduates needing a minimum AFQT Test score of 65.

Frequently Asked Questions

What types of tech jobs are available in St. Louis, MO?
St. Louis offers roles from software engineering and data science to cybersecurity, DevOps, UI/UX design, AI/ML research, and product management. The city’s healthtech and fintech sectors demand specialists in electronic health records, blockchain, and regulatory tech, while logistics firms need supply‑chain analytics and IoT developers.
How do remote and on‑site trends look in St. Louis?
Many companies now support hybrid models, with on‑site work preferred for roles that require collaboration, such as product design or systems engineering. Pure remote positions are common in software development and data analysis. Companies like Enterprise and Vontel offer flexible schedules, but a 3‑day on‑site requirement is typical for senior engineering roles.
Who are the major employers in St. Louis?
Key employers include BJC HealthCare, Enterprise Holdings, Eli Lilly & Co., Vontel, City of St. Louis, and the St. Louis Science Center’s research labs. Additionally, the city’s startup ecosystem includes companies such as Glean, Tasty, and the Midtown tech incubator, all actively hiring tech talent.
What are salary expectations for tech roles in St. Louis?
Median base salary for software engineers in St. Louis is around $95,000, with senior roles reaching $120,000+. Data scientists average $98,000, while cybersecurity analysts earn $88,000. These figures exceed the national average for comparable roles, reflecting the city’s focus on high‑growth industries. Transparent listings on Job Transparency help you benchmark offers against local market rates.
What advice is there for relocating to St. Louis for tech work?
Plan your move by researching neighborhoods: Midtown and the Central West End offer vibrant tech scenes and affordable housing; the St. Louis Riverfront and Oakville provide quieter options with easy access to downtown. Use Job Transparency’s salary tool to confirm that offers cover living costs. When interviewing, ask about relocation packages, housing stipends, and the company’s remote policy. Finally, tap local networking groups such as the St. Louis Tech Council and meetups to accelerate integration.

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