Jobs at Click Therapeutics
249,921 open positions
Chief Human Resources Officer
Company: Scribe Therapeutics
Location: East Bay
Posted Nov 29, 2023
All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, disability, age, or veteran status. The pay range offered will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data. At the time of posting, the base pay wage range for this role varies according to level, per year. We will provide an intellectually stimulating, collegial and fast-paced environment. Visit us at www.scribetx.com. BS degree in Human Resources, Business Administration, or related field is highly desired. Deep and broad knowledge of HR processes such as workforce planning, performance management, talent reviews, and change management. Foster a driven, fast-paced, dynamic, and fun environment in which to do rigorous science Required Skills and Background: Prior experience leading the HR function, with an established track record of delivering results. Salary will be commensurate with experience. At least 12 years of experience in HR leadership roles within high growth companies Demonstrated success in fast paced, innovative biotech/life sciences companies, both privately and publicly held.
Lead Statistician
Company: Spark Therapeutics, Inc.
Location: Philadelphia, PA
Posted Nov 25, 2023
Experience supporting DSURs, IBs and DMCs. Provide statistical support and outputs for conference presentations, manuscripts, CSRs, DMCs, etc. Collaborate cross-functionally (e.g., data management, programming, safety, clinical, etc.) Excellent verbal and written communications skills, strong presentation skills, able to translate statistical concepts to non-statisticians. Contribute to external engagement with consultants, advisory boards, health authorities, congresses, and scientific meetings. Deep and broad statistical training and experience in methodologies such as Mixed Models, Bayesian adaptive designs, Interim Analyses including Futility, Modelling and Simulation methods, and in SAS, R. Experience writing statistical analysis plans and mock TFLs for clinical study reporting. Develop/Write statistical standard operating procedures (SOPs) and input into general standardization efforts (e.g., CDISC, TFLs, eCRFs). Spark takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary for potential new employees. Extensive experience reporting clinical studies to CDISC standards. Expertise and experience in ADaM specifications and datasets Key Skills, Abilities, and Competencies Expertise and experience with Bayesian adaptive designs in early clinical development, Bayesian Go/NoGo decision framework for Stage Gate for End of Phase 2, and sample size re-estimation.
Senior Financial Analyst (Must Have General Ledger Accounting Experience)
Company: Scorpion Therapeutics
Location: Boston, MA
Posted Nov 23, 2023
We do not discriminate for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Beginning October 13, 2021, Scorpion Therapeutics requires all new hires to be fully vaccinated against COVID-19. Ability to present financial information to a non-financial audience, excellent communication, interpersonal, and presentation skills. High aptitude in Excel Modeling. Qualifications: Bachelor's degree in finance, accounting, or a related field 3-5 years of proven experience in financial planning, analysis, and modeling is required. Biotech experience and experience with NetSuite preferred. Strong analytical thinking and problem-solving skills. Help develop, apply, and implement the best tools to analyze data including sophisticated Excel financial models and planning analytical tools. If you are unable to receive the vaccine due to a disability or serious medical condition, or because of your sincerely held religious beliefs, you will have an opportunity to request a reasonable accommodation. Strong organizational skills with the ability to collaborate and partner across teams.
Head of Commercial Strategy & Pipeline Planning
Company: CymaBay Therapeutics
Location: North Jersey
Posted Nov 22, 2023
Professional Experience: Bachelor's degree with 12+ years of experience in biotechnology, pharmaceuticals, or consulting with a focus in one or more areas of global commercial strategy, new product planning, global analytics and pricing, access operations, and/or ex-US marketing MBA, Ph.D. in Life Sciences, or M.D. Ability to lead, influence, and gain consensus across cross functional team of Clinical Research, Regulatory, Legal, CMC, Finance and Commercial strategy in assessing life-cycle opportunities and market expansion opportunities for senior leadership Conduct commercial assessments for new assets, TAs or products, including epidemiology, competitive market, KOL advisory, pricing, and revenue assessments Serve as an effective liaison between the Development team and Commercial in an effort to advocate for new programs and/or asset to enhance portfolio value Manage process of creating target product profiles (TPPs) and label foals to influence clinical protocol development and study or program design Ethics and principles aligning to CymaBay’s mission and vision. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. CymaBay is a multi-state employer, and this salary range may not reflect positions that work in other states. is preferred Exceptional reputation as a commercial strategist and/or Product or Compound Development lead and partner with cross functional partners Experience within Business Development or commercial leadership within a BD team is preferred Track record of “influencing without authority” in successful conflict resolution, and driving to consensus Proven history of working and delivering on multiple projects simultaneously with tight deadlines and changing priorities is required Experience in successfully presenting to senior leadership audiences, including simplifying complex materials, educating, and managing audiences with differing viewpoints to achieve alignment Passion and vision for commercial strategy, long-range planning, and value creation The anticipated salary range for this role is $250,000 - $300,000. Conducting global business assessment for all considered TA strategies and assets, including market landscape assessments, addressable patient opportunity, product and portfolio differentiation, market access and pricing potential, and revenue projections/NPV analysis Leading life-cycle planning for seladelpar, CymaBay’s lead asset in development, in collaboration with cross department leadership, taking ideation through concepting, evaluation, budgeting and final recommendation; resolve issues and risks as they arise during the assessment and recommendation phases Evaluating global expansion opportunities for all product and pipeline assets through company infrastructure build-out, partnerships and/or distributer models Partnering with Business Development to acquire or in-license clinical stage assets to fuel CymaBay pipeline and future revenue Executing end-to-end business cases and pulling through all aspects of product and portfolio growth strategies, including clinical development program and study design, market research, analytics and forecasting, key opinion leader input and support, and final recommendation presentation to senior leadership and board-level for approval Developing scientific and commercial insights and strategies across life-cycle initiatives that will allow for prioritization and tradeoffs ahead of formal recommendations and approval; critical understanding of the value of eliminating options as part of total portfolio advancement Working across the company to ensure each program has a strategic direction, pathway to market, and alignment on product/programs goals and objectives Creating long term portfolio views to provide visibility to company’s pipeline growth (e.g., quarterly management review, board of director reviews, earnings/ analyst days) Ensure compliance with all CymaBay values and ethics, and relevant industry regulations and guidelines Qualifications for Role: Expertise leading portfolio or TA strategy and decision-making to ensure company strategic vision aligns with portfolio level decision-making Steeped in leading and achieving results for life-cycle-management, portfolio expansion, and pipeline asset evaluation. Key Responsibilities: The Head of Commercial Strategy & Pipeline Planning will be accountable for: Providing strategic leadership and oversight for product, portfolio and pipeline expansion opportunities through indication selection, target product profiles, clinical trial design and full development programs, and competitive positioning during the discovery and development process. While reporting specifically to the VP Franchise Lead, this role will require high levels of collaboration and partnership with cross-functional leaders in other departments such as Business Development, R&D, Medical Affairs, Clinical Development, Market Access, and Commercial Operations to develop strong commercial positions leading to additional company investments and long-term sustainable growth. Ideally, candidates for the Senior Director role must have the proven ability to conduct detailed global commercial assessments, support clinical development from early phases through product approval, and provide detailed analyses and final recommendations for all prospective product/portfolio opportunities. This is a hybrid role - our work from home days are Monday and Friday and our in-office days are Tuesday, Wednesday and Thursday.
Research Associate/Senior Research Associate, Process Development
Company: LEXEO Therapeutics
Location: New York City, NY
Posted Dec 01, 2023
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment. New York, NY Primary Responsibilities Develop bioreactor-based cell culture processes for manufacturing of AAV-based gene therapy vectors across multiple programs With guidance, optimize expression and harvest processes for improved consistency, performance, and product quality Support scaleup and process transfer to manufacturing groups; including scale down experiments, and authorship of technical documents Plan and prepare for reliable execution of experiments, including maintaining inoculum cultures, ensuring availabilities of reagents, and preparation of equipment Coordinate experiment activities within department, including purification and analytical teams Evaluate new and emerging technologies as they relate to cell culture processes Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system Present scientific data to colleagues at internal meetings Required Skills & Qualifications BS/MS degree with 0-2+ years of relevant experience in Chemical Engineering, Biomolecular Engineering, Biomedical Engineering, Biotechnology, Biochemistry, Microbiology, or related fields Hands-on experience with cell culture Solid understanding of aseptic technique Enthusiastic learner with an attention to detail A demonstrated knowledge of and interest in cell biology Ability to design scientifically sound experiments under guidance, to interpret results, and to present findings Effective written and oral communication skills Depending on qualifications and overall experience, base salary is likely to be $75,000-$90,000 per year. Location Lexeo Office. You will have an opportunity to learn in a fast-paced startup company, while working collaboratively within a multidisciplinary team that is dedicated to the development of new therapies. As an early hire at a new company, you will have exposure to senior management, and you will be influential in championing and developing Lexeo’s culture. Role Summary Reporting to the Director, Process Development, this position will be responsible for developing and optimizing the production of AAV therapeutic candidates in the lab, with collaborators, with the goal of advancing the development of novel targets for cardiac and neurodegenerative disorders.
Scientist/Sr Scientist, Analytical Development
Company: Strand Therapeutics
Location: Boston, MA
Posted Nov 29, 2023
Strand offers a fast-paced, entrepreneurial, team-focused work environment. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. We also offer a top-notch benefits package (health, dental, life, vacation, 401k, and commuter) and work/ life integration. Excellent organizational skills. Independently motivated, detail oriented and good problem-solving ability. Degree emphasis in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field preferred. Experience working with vendors. Understanding of nucleic acid chemistry, enzymatic and chemical reactions, PCR, plasmid processing, and standard production techniques for RNA/LNP. Strand Therapeutics is an equal opportunity employer. Knowledge of GMP/ICH/FDA regulations strongly preferred.
Senior/Principal Research Associate (Histology)
Company: Voyager Therapeutics
Location: Cambridge
Posted Nov 28, 2023
JMP, GraphPad Prism) and general programming languges (Python, R) Exhibit excellent oral and written communication skills Requirements: Educational Requirements: Senior Research Associate: BS with 3+ years or MS with 2+ years of relevant industry experience Principal Research Associate: BS with 5+ years or MS with 3+ years of relevant industry experience Experience: Knowledge and working experience with the anatomy of brain and spinal cord of rodents, non-human primates, and human Experience with using IHC/ISH automated staining systems preferably Leica BondRx or Ventana Discovery Ultra Experience in image acquisition using; whole slide scanners ( Olympus VS 200 or Aperio Versa, GT450), epifluorescence and confocal microscopy Experience and knowledge of relevant image analysis software packages: HALO, HALO-AI, ImageScope, Visiopharm and their corresponding AI machine/deep-learning modules, spatial analyses, and heat maps. Nanostring’s Digital Spatial Profiling or Spatial Molecular Imager, in-situ sequencing, MERFISH or Visium spatial transcriptomics) Working knowledge of statistical programs (eg. For more information, visit www.voyagertherapeutics.com. Position Specific Responsibilities: Handle and process fresh frozen and fixed nervous- and peripheral-tissues from rodents, non-human primates, and human Develop and perform novel tissue-based staining methodologies immunohistochemistry (IHC), immunofluorescence (IF), and in-situ hybridization (ISH) assay development (including use of automated equipment [Leica Bond]) Knowledge of subsequent image acquisition and qualitative or quantitative analysis of stained tissues Present the histology data in program or research group meetings Contribute to experimental design, planning, and execution of research projects Ability to adapt and exercise flexibility for projects and workflows Ability to collaborate with project team members and peers to anticipate and resolve day-to-day issues working in a matrix organizational structure Strong organizational skills, attention to detail, desire to learn new techniques and contribute to projects Specialized Knowledge & Skills: Knowledge and working experience with the anatomy of brain and spinal cord of rodents, non-human primates, and human is strongly preferred Familiarity with newer histology-based precision profiling techniques and data analysis (eg. Job Summary: The Senior/Principal Research Associate, Histology is a highly motivated biologist that contributes to the Voyager research team. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. They are enthusiastic about biomedical research and work collaboratively with other scientists and team members. The individual helps the group conduct innovative drug discover research while meeting deadlines and company goals. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors.
Associate Director, Forecasting
Company: CymaBay Therapeutics
Location: North Jersey
Posted Nov 22, 2023
CymaBay is a multi-state employer, and this salary range may not reflect positions that work in other states. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. The employee is occasionally required to stand. While performing the duties of this job, the employee is regularly required to talk and hear. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. The noise level in the work environment is usually moderate The anticipated salary range for this role is $170,000 - $195,000. Must have strong task management skills to include planning, prioritization, objective setting, and meeting management and plan execution Teamwork - ability to work effectively in, and foster, a team environment; consultative with a willingness to learn, teach and grow Travel: Limited travel up to 20% PHYSICAL DEMANDS AND WORK ENVIRONMENT The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. The employee must occasionally lift and/or move up to 25 pounds. The employee frequently is required to walk and sit.
Executive Assistant
Company: Scribe Therapeutics
Location: East Bay
Posted Dec 02, 2023
All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, disability, age, or veteran status. Expertise with G-suite (Gmail, docs, spreadsheets, slides). The offered pay range will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data. expense reports, booking travel, planning celebratory team events, etc. We will provide an intellectually stimulating, collegial and fast-paced environment. Proficiency in commonly used software and technologies, such as video conferencing, and collaboration tools. Facilitate key staff meetings by structuring agendas, taking notes, and organizing work streams. Visit us at www.scribetx.com. Planning and coordinating onsite/offsite meetings, including large scale events. At the time of posting, the base pay wage range for this role is $100,000-145,000 per year.
Associate Director/Director, Cheminformatics
Company: Matchpoint Therapeutics
Location: Boston, MA
Posted Dec 01, 2023
All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, marital or veteran status, disability, or any other legally protected status. Matchpoint is an equal opportunity employer, seeking to create a welcoming and diverse environment. Key Responsibilities / Essential Functions Partner with leadership team to set vision and strategy for cheminformatics as it applies to drug discovery and chemoproteomics platform Develop and deploy DL/ML models for drug discovery projects Analyze in vitro and ADME properties to inform improved design in covalent drug discovery programs Drive molecular design by working closely with internal and external computational chemistry colleagues Develop and deploy analysis and visualization tools for medicinal and computational chemists, as well as for chemoproteomics experiments Qualifications/ Year(s) of Experience / Education Requirements / Competencies Ph.D. or equivalent in physical chemistry, organic, computational chemistry, cheminformatics, physics, and/or computer science 8+ years of cheminformatics experience in biotech/pharma Proven track record of impact and innovation as evidenced by authorship and/or inventorship Ability to communicate results and proposals to all levels of the organization and to influence molecule design and med chem program strategy Ability to work effectively in a globe-spanning virtual team and adjust priorities as required to meet evolving company needs and deadlines Previous experience contributing to covalent drug discovery is desirable We offer a competitive compensation package, including equity-based compensation, annual bonus potential, healthcare benefits, 401(k), parking, and flexible paid time-off. The incumbent will collaborate with multidisciplinary colleagues across the research team, as well as with external scientific domain experts, and have the skills to influence and manage science both internallyand externally. Additional experience is in applying DL/ML techniques to generative molecular designs, use of cheminformatic tools to analyze chemoproteomics data, and in analysis of DEL experiments is highly preferred. The successful candidate will partner with Matchpoint’s leadership team to develop and execute on a vision and strategy for state-of-the-art cheminformatic tools in covalent small molecule drug discovery. Position Summary Matchpoint Therapeutics is looking for a talented, driven cheminformatician with a proven track record in advancing drug discovery pipelines. The successful candidate will have extensive experience in cheminformatics; using state-of-the-art deep learning/machine learning (DL/ML) tools in developing models that impact programs. Founded in 2021 by Atlas Venture and Access Biotechnology together with leading scientists from the Dana Farber Cancer Institute and Stanford, we are rapidly growing our team and looking for passionate, driven, and creative thinkers to join us in ushering in a new era of covalent medicines. The company's proprietary Advanced Covalent Exploration (ACE) platform integrates advanced chemoproteomics, machine learning and covalent chemistry library evolution.
Associate Director/Director, QA Systems and Training
Company: CymaBay Therapeutics
Location: North Jersey
Posted Dec 01, 2023
Prior experience with quality management and training systems (i.e, paper, hybrid, cloud-based) Proven track record of successful process improvement initiatives. Solid organizational skills and attention to detail Self-motivated and self-disciplined Always acts with integrity and respect to others Excellent computer proficiency (MS Word, Excel, PowerPoint) EDUCATION, CERTIFICATES, LICENSES, REGISTRATIONS Bachelor of Science degree The anticipated salary range for AD, QA Systems & Training in Newark, California is $170,000 - $185,000 and Director, QA Systems & Training is $185,000 - $215,000. Adaptable to a fast-paced, complex, and ever-changing business environment Excellent verbal and written communications skills effectively interfacing with internal stakeholders. Support regulatory inspections. CymaBay is a multi-state employer, and this salary range may not reflect positions that work in other states. The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Analyze and report on quality metrics, trends, and performance. Complete other responsibilities, as assigned MINIMUM QUALIFICATIONS Minimum 5-7 years of relevant experience in Quality focused on document control and training. Acts as the Veeva Quality Docs and Vault Training business system owner to support ongoing validation, implementation, and system configuration changes, inclusive of testing new functionality and content for the quality docs and learning platform. Lead the efforts to consistently enhance quality systems and training content, driving continuous improvement initiatives forward.
Sr. Research Associate, Vector Genome
Company: Voyager Therapeutics
Location: Cambridge
Posted Nov 25, 2023
Experience with protein-protein interaction techniques such as Biacore/SPR, Octet/BLI, ITC, etc. Hands-on experience in common protein characterization techniques (SDS-PAGE, Western Blotting). Ability to be highly productive and self-motivated in a fluid, fast-paced and team environment. Strong knowledge and wet-lab experience performing ELISA based protein quantification assays. Outstanding problem solving and troubleshooting skills. Execute biomolecular interactions assays using Biacore/SPR and Octet/BLI techniques to measure kinetics, affinity, competition, and epitope binning. Perform small scale expression and purification of proteins (antibody and antibody conjugates, enzymes, fusion proteins). Regularly communicate results within the research organization. Perform traditional ELISA and AlphaLISA based immunoassays for protein quantification in a variety of sample types (culture media, serum, CSF and tissues). Experience with protein expression in mammalian cells and protein purification using various chromatography methods and instruments such as AKTA FPLC.