Tech Jobs in Cambridge
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Cambridge's tech scene thrives at the intersection of world‑class research institutions like MIT and Harvard, a dense network of venture capital, and a culture that nurtures startups. The city attracts talent in AI, data science, and cybersecurity, driving demand for software engineers, machine learning specialists, and product managers.
Cambridge hosts a diverse roster of tech firms—from global pharma leaders such as Gilead Sciences and Boston Scientific to cloud‑native companies like HubSpot and Wayfair. Start‑ups like Ginkgo Bioworks, Butterfly Network, and Clari focus on biotech innovation, while IBM Research and MIT Lincoln Laboratory push the frontier of quantum computing and secure communications. This mix creates opportunities across hardware, software, fintech, and biotech sectors.
While the median rent for a one‑bedroom apartment in Cambridge tops $3,000/month and the city’s overall cost index is high, salaries often exceed national averages. Transparent salary data on Job Transparency allows candidates to benchmark offers, negotiate effectively, and align compensation with the true value of living in a high‑cost market.
Senior Program Director - Bio Innovation Hub
Company: Novo Nordisk
Location: Cambridge
Posted Sep 25, 2023
Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations. Together, we're life changing. Novo Nordisk is an equal opportunity employer. If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. Qualifications MS or MD, Degree within natural sciences is required, PhD and/or MBA strongly preferred 15+ years' relevant professional experience (if applicable, PhD time included): Project management experience leading cross-functional projects (prefer 5+ years in global projects); experience managing larger programs (not individual projects) is preferred Previous experience managing strategic alliances with demonstrated value creation is preferred Ability to run programs and projects independently and in close cooperation with colleagues across Novo Nordisk to ensure a holistic strategic solution to often multifaceted business problems As decisions involve coordination with other internal stakeholders in the HQ organization, affiliates, and external stakeholders, the ability to successfully navigate internal dynamics is required and experience working in a matrix organization preferred Demonstrated ability to present to, influence and build rapport with senior management Understanding the interface btw Legal, business development and alliance management Strong scientific and business understanding across R&D, and ideally experience from translational medicine / pre-clinical drug development Strong intercultural understanding and global collaboration capabilities both internally and externally High capacity for idea generation, hypothesis testing and problem solving, the ability to consolidate large amounts of complex information in a dynamic environment and to think outside the box to arrive at creative solutions Excellent collaboration, influential leadership skills and an ability to learn the Novo Nordisk business and organization, as well as the general pharma/biotech industry, is preferred Ability to motivate and influence others to advance goals, and the ability to effectively manage multiple projects or roles in a rapidly evolving environment Demonstrated ability to make strategic recommendations and manage risk with timely go/no-go decisions at all stages of the project/program delivery process Knowledge about different cultures, practices and procedures often required Demonstrates excellent verbal and written communication skills Proficient in Microsoft Office suite of products (Outlook, Excel, Word, PowerPoint) We commit to an inclusive recruitment process and equality of opportunity for all our job applicants. Ensure identification of best practices internally and externally and facilitate continuous improvement and innovation with the overall program, overall serving as a committed role model externally as well as internally Draw on and delegate into Line of Business and across Novo Nordisk SVP areas through multiple levels of employees and scientific experts to drive outcome, based on a clear sense of direction High independence and initiative should always be demonstrated when planning for, improving and performing tasks assigned by management In general, decisions are complex and involve coordination with other internal stakeholders in the HQ organization, affiliates, and external stakeholders for this position Assignments are characterized by high variability, complexity, and often by lack of precedence Actively connect and feed knowledge into the Global Novo Nordisk R&D organization, with a specific focus on diverse innovation approaches and lean project plan executions (early program and project de-risking), new ways of working, as well as asset transitioning Expected to actively challenge the ordinary processes and priorities upwards in the organizational hierarchy up to Executive Vice President level As the anchor of Quality, Improvement, and Knowledge sharing, this role requires the ability to identify better practices and create improvements in processes and approaches, as well as proactive action on quality and compliance-related matter Responsible for documentation and strategies required for regulatory submissions Ensure working in compliance with QMS, EHS and OHS standards Physical Requirements 0-10% overnight travel required. budget responsibility (15-70m USD) with the Bio Innovation Hub's strategic partners and collaborations, and manage and nurture existing business partnerships to maximize the value to Novo Nordisk Proactively engage with the core R&D organization to solve scientific challenges identified during product concept development and utilize the DK based Navigators to transfer assets, scientific challenges, and knowledge to the core research and early development organization Drive translational R&D plans for novel product concepts, actively engage with cross-functional Novo Nordisk R&D teams to execute on co-created R&D plans and ensure that decisions are guided by scientific and translational priorities, even when complex analysis of situations and data is required. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. The role will be the interface between the Bio Innovation Hub and the greater NN organization, including engaging with colleagues in Global Drug Discovery and Research Technologies, as well as the wider R&D organization across EVP/SVP areas. The holder of this role is responsible for managing a portfolio of projects that each require cross-functional teams operating across 2-3 companies, including biotech companies, venture capital firms, and academic institutions typically interacting at C-level in Joint Steering Committees.
Lead Specialist, Quality Assurance
Company: 2seventy bio
Location: Cambridge
Posted Sep 23, 2023
Perform daily operations within the eLMS, such as managing training items and curriculum, modifying user accounts, creating reports, and system troubleshooting. Lead, guide, and train staff/student employees, interns, and/or volunteers performing related work; may participate in the recruitment of volunteers, as appropriate to the area of operation. Select or develop training aids in collaboration with department management, including training handbooks, demonstration models, multimedia visual aids, computer tutorials, and reference works. Work cross-functionally to formulate training outlines and determine instructional methods, utilize knowledge of specified training needs and effectiveness of such methods as individual training, group instruction, lectures, demonstrations, conferences, meetings, and workshops. Experience may be gained concurrently and must include:Three (3) years in each of the following:- Leading and facilitating trainings for individuals and departments- Preparing instructional aids and plans- Applying knowledge of GxP regulations, quality systems, and guidance documents including ICH- Managing all aspects of training including determining objectives, designing, developing, implementing, and evaluating training plans, curricula, and methodology.One (1) year in each of the following:- Working with Document Control- Utilizing ComplianceWire- Implementing and validating electronic systems for management of user training.2seventy bio has a mandatory vaccination policy for the COVID-19 vaccination for all employees, contractors and consultants as of January 4, 2022. May review instructor performance and recommend improvements to program content and/or instructor presentation methods; may recruit, select, and train instructors. Position reports into Cambridge, MA office; however, telecommuting from a home office may also be allowed.Requirements: Requires a Bachelor’s degree in Health Information Technology, Biotechnology, or a directly related scientific field plus three (3) years of experience organizing or conducting training in a GxP regulated industry. In accordance with 2seventy bios duty to provide and maintain a workplace that is free of known hazards, we are adopting this policy to safeguard the health of our employees, contractors, consultants and their families, and the community at large from infections disease that may be reduced by vaccinations. Coordinate Training eLMS administrative functions, including processes, logistics, delivery, metrics, and maintenance while identifying and effectively resolving quality issues or discrepancies. Deliver group and individual instruction and training covering a range of technical, operational, and/or management areas including new hire orientation.
Executive Assistant, Legal & Compliance
Company: Amylyx
Location: Cambridge
Posted Oct 06, 2023
We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical matters), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. Support the Chief Legal Officer & General Counsel in preparing agendas, collecting and reviewing presentation materials, reserving conference rooms and coordinating video conferences (MS Teams, Zoom, etc. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. including opening and closing POs, processing invoices, onboarding new vendors, managing vendor offboarding process.Partner with other Executive Assistants to organize corporate events and meetings and Extended Leadership Team meetings. Work with Legal/Compliance functional leaders to build annual budget, ensuring new line items are assigned to appropriate budget code; track and review quarterly forecast.Support the Legal/Compliance team with the management of POs, invoices, etc. ).Make recommendations for new ways of managing workflows and process improvements as needed.Develop collaborative relationships with the Executive Assistant to the Co-CEOs, the Executive Assistant to the CFO, the Executive Assistant to the CCO, and the Executive Assistant to the CHRO providing back-up support as needed.Coordinate domestic and international travel as well as process travel & expense reports for reimbursement.REQUIREMENTS8+ years of experience supporting C-Level executives.Bachelor’s Degree and Legal experience a plus but not required.Excellent organizational and prioritization abilities with meticulous attention to detail.Strong interpersonal and communication skills with the ability to build and nurture relationships with stakeholders, including employees at all levels, executives, and board members.Incredibly proactive; able to anticipate needs and prioritize day to day work and projects based on the demands of the business.Anticipate and resolve issues.Proven time management skills with the ability to handle multiple tasks, execute effectively against multiple projects and deadlines, and remain cool under pressure.Demonstrated ability to operate independently, use sound judgement and professionalism.Applies confidentiality and accuracy to work and interactions with employees and external partners.Demonstrated proactive approaches to problem-solving,Resourceful team-player, with the ability to also be extremely effective independently.Highly proficient in Microsoft Office Suite and an ability to learn additional project management and collaboration tools.Contracts Management Systems experience preferred.Able to work cross-functionally in a matrix environment.Years of experience and educationTo stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn. Provide support in the preparation of executive and Board of Directors materials, helping to iterate presentations, reviewing documents for content flow and accuracy.Support the Chief Legal Officer & General Counsel in preparations for monthly Board meetings, ensuring meeting materials are received on time, providing presenters with guidance on effective presentations, coordinating with the Executive Assistant to Co-CEO’s to understand potential conflicts.Support other members of the Legal & Compliance department for various administrative needs across the function, including but not limited to supporting the Global Compliance Officer in implementation of the compliance program, Intellectual Property docket management, tracking state licensures, issuing and tracking litigation holds, and supporting implementation and upkeep of a contract management system.Manage Legal & Compliance budget, tracking budgeted and unbudgeted spend against Purchase Orders (PO) and invoices, and providing awareness on actual to budget. Must be a team player, responsive and able to function independently, manage highly confidential and sensitive information and matters with the utmost discretion.The person in this role will have exceptional written and verbal communication skills, with the ability to create and edit communications, meeting notes when required, meeting preparation materials, and presentations, ensuring accuracy, attention to detail, and follow through. This position offers a unique opportunity to be part of a highly respected Legal & Compliance team and support a key leader in the organization.RESPONSIBILITIESWork closely and effectively with the Chief Legal Officer & General Counsel, providing support in organizing meetings and calendar management, prioritizing appropriately.Draft and/or edit materials including documents, PowerPoint presentations, and reports. In this visible role, the Executive Assistant, Legal & Compliance is responsible for proactively listening, anticipating and meeting priorities in a fast-paced environment.
Archive-Submittals Coordinator
Company: SMMA
Location: Cambridge
Posted Sep 22, 2023
We are guided by a shared pursuit of design excellence, sustainability, and social responsibility. Company Perks Employee-owned firm with Employee Stock Ownership Program Hybrid work-from-home policy Competitive benefits including paid time-off, company-funded MA Paid Family and Medical Leave, company-paid dental plan, company-paid life insurance, and 401(K) matching Employee Assistance Program (includes confidential emotional support, legal guidance, and financial resources) Mentor/protégé program Educational reimbursement Licensure and membership reimbursement “Lunch and Learns” with internal and external speakers Today, we remain dedicated to this flexible, integrated approach. Our work straddles seven markets—K-12, Higher Education, Corporate, Commercial, Life Science, Federal Government, and Advanced Technology—with the opportunity to work across a wide range of projects and specialisms. Cambridge-based since our incorporation in 1955, we offer an integrated, multidisciplinary environment driven by collaboration between architects, interior designers, engineers, technologists, researchers, and industry experts. We offer a fast-paced, team-oriented environment that promotes intellectual and creative growth. SMMA was founded by MIT and Rensselaer alumni who believed that the balance of architecture, engineering, interiors, and site design afforded clients the agility of a single source of creative and technical expertise. Key Archive Responsibilities Assist with digital asset management, records management, and project close-out activities Organize and inventory drawings and project documentation Preserve and rehouse archival material in various formats Assist with the preparation of archival materials for transfer to off-site storage and clients Key Submittals Responsibilities Process and track shop drawings and samples with respective trades (Ex: architectural, structural, MEP, specialist consultants) Coordinate with respective trades, contractors, and consultants during construction phase Prepare shop drawing status reports Respond to technical and coordination issues related to tracking of shop drawings Set up QC reviews and coordinate with project managers, consultants, and clients Secondary Responsibilities As needed additional support for administrative team members to cover vacations and absences. Print Room services: Printing, coordinate delivery services, travel arrangements, and mail distribution Administrative services: catering requests, meeting arrangements, and occasional reception coverage Key Competencies Proficient with Bluebeam, Acrobat, and MS Office including Word, Excel, Teams, and Outlook Ability to work in a team environment and on an individual basis Ability to communicate both verbally and in writing Good interpersonal skills and attention to detail Ability to work well under pressure Well-organized and flexible, with the ability to prioritize tasks in a fast-paced environment Strong organizational, interpersonal, and communication skills Minimum Qualifications Current college student actively pursuing a degree in Architecture, Engineering, or Interior Design Technical knowledge of the AE industry or experience as a librarian Two years of general office experience Ability to lift and carry boxes weighing up to 40 pounds and move furniture Ability to stand, stoop, bend, and work in tight spaces About the Firm SMMA is one of New England’s most unique design firms due to our composition, reputation, and focus. We focus on building lasting relationships with strategic partners in both the public and private markets. As an employee-owned firm, we believe that good ideas are welcome from anywhere. The primary responsibility of the Archive/Submittals Coordinator will be to maintain control over project archives and shop drawings through a computerized database and to ensure proper filing, storage, and retrieval of documents. The secondary responsibility will be to provide print room and administrative support. SMMA is seeking an Archive/Submittals Coordinator to handle project document archiving maintaining control over a computerized database of historic project information, and to manage project submissions and approve shop drawings and samples from consultants.
Director - Alliance Management
Company: Novo Nordisk
Location: Cambridge
Posted Sep 26, 2023
Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations. Together, we're life changing. Novo Nordisk is an equal opportunity employer. The job requires global collaborations with R&D teams based in Denmark, China, and Boston, Seattle, and Indianapolis within the US. The Director will report to the Corporate VP of Early Innovation, Outreach & Alliances, and be tethered administratively to the VP, Site Head of Novo Nordisk Research Center Seattle, Inc. If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. Qualifications Ph.D. or MD with 8+ years or a Master's with 10+ years within medicine, science, pharmacy or similar required. The Director shows solid communication skills, contextual understanding, shows ability to influence a project team, and shows solid contractual understanding. Essential Functions Ensure optimal negotiation of contracts relevant for Novo Nordisk alliances Support portfolio of alliances towards agreed milestones and outcomes Develop, suggest, and champion new alliances in alignment with the R&D strategy In collaboration with relevant dept. The Director provides solid oversight, enables, and monitors a significant range of alliance management activities, is involved in the deal negotiation, stirs governance set-ups of certain complexity, and has a diverse portfolio of alliances.
Senior Research Associate/Scientist, Biochemistry & Biophysics
Company: MOMA Therapeutics
Location: Cambridge
Posted Oct 03, 2023
MOMA Therapeutics is seeking a Research Associate/Senior Research Associate/Scientist to join their experienced and collaborative team. The role involves developing and executing novel biochemical and biophysical assays, exploring new technologies, and interpreting data for drug discovery programs. The ideal candidate has a background in biochemistry or biophysics, expertise in fluorescent-based techniques, and experience with enzymology. They should be a team player, enjoy working in a lab, and thrive in a data-driven environment.
Contract - Process Engineer II
Company: Vedanta Biosciences
Location: Cambridge
Posted Sep 24, 2023
Vedanta was founded by PureTech Health and a team of world-renowned experts in immunology and microbiology. We invite you to explore our site to learn more about our company and how our discovery platform enables identification of bacterial consortia with drug-like properties and their manufacture to GMP standards.Our Vision:We are harnessing the human microbiome to enable a new drug modality based on rationally defined bacterial consortiaVedanta is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Technical writing skills required.Ability to thrive within a fast-moving, dynamic environment. Vedanta will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Vedanta Biosciences requires all employees to be fully vaccinated against COVID-19 and newly hired employees must be fully vaccinated prior to their employment start date. Title: Contract - Process Engineer IILocation: Cambridge, MA Reports to: Associate Director, Technical Operations The Role:The Process Engineer II will be responsible for working cross-functionally to design, scale, and implement processes in Vedanta’s manufacturing facilities. Vedanta Biosciences will consider accommodations for individuals who are unable to be vaccinated against COVID-19 due to a qualifying medical condition or disability or a sincerely held religious objection. This role can be a fully onsite role, or could be a hybrid role with up to 1 or 2 days per week being remote.Here’s What You’ll Do:Assist in tech transfers within a multiple-site manufacturing enterprise in support of high throughput/demand.Participate in day-to-day Tech Transfers including but not limited to manufacturing, manufacturing support, and manufacturing compliance to ensure delivery of departmental commitments to achieve company objectives.Assist in developing standardized documentation including SOP’s, training, validation of equipment, and reports.Drive results on multiple complex assignments, in addition to reviewing and guiding the work and performance of vendors/consultants.Contribute to decisions based on professional judgement, experience, budget, cGMP regulations, and ethical guidelines of good business practices.Requirements:Engineering degree or equivalent required.5+ years of engineering experience in a biomanufacturing or development environment with 3+ years in a GxP environment preferred.Excellent interpersonal and communication skills (verbal and written) are required. Breakthrough discoveries of our scientific team in the field of mucosal immunology have led to the first rationally designed drug candidates in the microbiome field. Embraces and drives change where appropriate.Why join Vedanta BiosciencesVedanta is pioneering the development of a new class of therapies that act by modulating the human microbiome. Modulation of the human microbiota holds enormous promise to treat a broad range of immune and infectious diseases in ways that are completely different to existing drug classes. This successful individual is a motivated and experienced process engineer who will focus on operations support, project execution, and tech transfer.
Senior Associate Scientist / Principal Associate Scientist – Upstream Process Development
Company: Generation Bio
Location: Cambridge
Posted Oct 05, 2023
We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. This role will have high visibility in a company that is expanding to support a dynamic pipeline.RESPONSIBILITIES:Primary responsibilities for this role include:Design, execute and analyze process development and characterization experiments for enzyme-based production of DNA-based drug substanceDocument experimental execution and analysis via electronic lab notebookEstablish scale-down process models and perform process characterization utilizing DOE principlesSupport development and optimization of RES ceDNA production and process methodologies for lead candidate and subsequent platform programs.Create and edit documentation including protocols, SOPS, batch records, reports.Identify and/or optimize unit operations to improve robustness, cycle time, throughput, and cost while maintaining product qualitySupport the development and optimization of the lead candidate through process innovation, and identification of key variables to improve process performancePrepare, analyze, and present data internally to cross functional teamsQUALIFICATIONS: Degree in Molecular Biology, Bioengineering, Cell Biology or related disciplineMinimum of 2 years of relevant industry experienceExperience in developing processes for synthesizing biologics, enzymatic reactions, and/or purification of complex biomoleculesUnderstanding and practical application of molecular biology techniquesSense of urgency, results-driven, and excellent attention to detailProven ability to work independently, effectively plan work activities, and prioritize task completion to meet schedules and deadlinesStrong collaboration and team-working skillsDesired experience:Knowledge of cGMP and regulatory guidelines and practices, and how these relate to and impact upstream developmentTrack record of managing multiple projects and responsibilities simultaneouslyExperience with high throughput screening technologies and developing enzyme activity assaysPOSITION: Full-Time, Non-ExemptEEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. RES has the potential to expand Generation Bio’s manufacturing scale to hundreds of millions of doses to support its mission to extend the reach of genetic medicine to more people, living with more diseases, around the world.We are a thriving, collaborative, creative community of 165 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts. Delve further. Please visit www.generationbio.com or follow @generationbio. To see additional roles, please also check out https://generationbio.com/careers/ SUMMARYGeneration Bio seeks an enthusiastic and highly motivated Senior/Principal Associate Scientist to guide Drug Substance Upstream Process development as part of the Chemistry, Manufacturing and Control (CMC) department. The Upstream Process Development team is focused on creating, optimizing and understanding the control strategy for our GMP compliant process. The platform is designed to enable multi-year durability from a single dose, to deliver large genetic payloads, including multiple genes, to specific tissues, and to allow titration and redosing to adjust or extend expression levels in each patient. The company’s non-viral platform incorporates a novel DNA construct called closed-ended DNA, or ceDNA; a unique cell-targeted lipid nanoparticle delivery system, or ctLNP; and a highly scalable capsid-free manufacturing process that uses its proprietary cell-free rapid enzymatic synthesis, or RES, to produce ceDNA. The successful candidate will have good laboratory skills and attention to detail to help develop and optimize enzyme-based production processes for DNA-based drug substance. Generation Bio is innovating genetic medicines to provide durable, redosable treatments for people living with rare and prevalent diseases.
CMC Technical Writer (Contract-to-Perm)
Company: Vedanta Biosciences
Location: Cambridge
Posted Oct 05, 2023
Vedanta was founded by PureTech Health and a team of world-renowned experts in immunology and microbiology. We invite you to explore our site to learn more about our company and how our discovery platform enables identification of bacterial consortia with drug-like properties and their manufacture to GMP standards.Our Vision:We are harnessing the human microbiome to enable a new drug modality based on rationally defined bacterial consortiaVedanta is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Title: CMC Technical Writer (Contract-to-Perm)Location: Cambridge, MAReports to: Director, CMC Operations & Strategic Planning The Role:This position will lead and assist in the writing and editing of technical documents such as investigations, whitepapers, protocols, technical reports, and regulatory submissions to make these documents as clear as possible and tailor them to the appropriate audience. Vedanta will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Vedanta Biosciences requires all employees to be fully vaccinated against COVID-19 and newly hired employees must be fully vaccinated prior to their employment start date. The individual must have a clear understanding of CGMP and current regulatory expectations within the life sciences industry.Here’s What You’ll Do:Partner with technical leadership and cross-functional partners such as Manufacturing, Quality, Process Development, Validation, and Facilities to implement appropriate written documentation.Integrate various sources of information into a uniform style and language for GMP and regulatory compliance.Work with initiators to rewrite, clarify, or reconstruct controlled documents and investigations.Write and edit standard operating procedures, test methods, technical/validation reports, regulatory submissions, investigations, and other related documents.Coordinate the review, approval, and revision of procedures, specifications, and forms.Requirements:Bachelor’s Degree and minimum 5 years of experience in technical writing within the life sciences/GMP environmentMinimum of 2 years’ experience with quality management systems and processes.Experience authoring and reviewing standard operating procedures, deviations, regulatory materials, training, and other controlled documents.Advanced proficiency using Microsoft Word.Ability to collaborate effectively; strong interpersonal skills and ability to work with colleagues that possess varying levels of writing proficiency.Experience with training others in writing/editing best-practices.Why join Vedanta BiosciencesVedanta is pioneering the development of a new class of therapies that act by modulating the human microbiome. Vedanta Biosciences will consider accommodations for individuals who are unable to be vaccinated against COVID-19 due to a qualifying medical condition or disability or a sincerely held religious objection. Breakthrough discoveries of our scientific team in the field of mucosal immunology have led to the first rationally designed drug candidates in the microbiome field. Modulation of the human microbiota holds enormous promise to treat a broad range of immune and infectious diseases in ways that are completely different to existing drug classes.
Sr. Research Associate, Vector Genome
Company: Voyager Therapeutics
Location: Cambridge
Posted Oct 05, 2023
This is an ideal position for an individual with a background in protein biochemistry, who has a can-do attitude and strong work ethic, and thrives in a team-oriented, fast-paced, and cross-disciplinary biotech environment. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. As a Senior Research Associate on the team, you will be responsible for experimental execution and data analysis of various biophysical and biochemical assays to support pipeline programs and new research initiatives.Position Specific Responsibilities:Perform biophysical and biochemical assays to characterize peptides and proteins to support multiple Voyager programs.Execute biomolecular interactions assays using Biacore/SPR and Octet/BLI techniques to measure kinetics, affinity, competition, and epitope binning.Perform small scale expression and purification of proteins (antibody and antibody conjugates, enzymes, fusion proteins).Perform traditional ELISA and AlphaLISA based immunoassays for protein quantification in a variety of sample types (culture media, serum, CSF and tissues).Conduct experimental procedures precisely and consistently by following established protocols, as well as document and maintain a well-organized account of lab work and results.Ability to adapt and exercise flexibility for projects and workflows.Regularly communicate results within the research organization.Educational Requirements & Experience:A minimum of a Bachelor’s degree with 3-4 years or Master’s degree with 1-2 years of lab experience in an industry or academic setting.Experience with protein-protein interaction techniques such as Biacore/SPR, Octet/BLI, ITC, etc.Hands-on experience in common protein characterization techniques (SDS-PAGE, Western Blotting).Experience with protein expression in mammalian cells and protein purification using various chromatography methods and instruments such as AKTA FPLC.Strong knowledge and wet-lab experience performing ELISA based protein quantification assays.Outstanding problem solving and troubleshooting skills.Ability to be highly productive and self-motivated in a fluid, fast-paced and team environment. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. For more information, visit www.voyagertherapeutics.comJob Summary: Voyager Therapeutics seeks a highly motivated and experienced protein biochemist to contribute to its research team at its facility in Cambridge, Massachusetts. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. About&8239;Voyager Therapeutics Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging cutting-edge expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints.
Machine Learning Scientist
Company: Flagship Pioneering
Location: Cambridge
Posted Sep 22, 2023
Experience comes in many forms, skills are transferable, and passion goes a long way. Exceptional candidates without PhDs will be considered.Experience developing, debugging, and applying models using modern deep learning frameworks on GPUs in cloud environments.Proficiency in Python and machine learning frameworks such as TensorFlow, Pytorch, and/or JAX.Desire to work across the entire data stack, from data ingest to model deployment.Curiosity and humility to work with scientific domain experts to identify and frame problems worth solving beyond existing benchmarks.Energetic self-starter with the ability to work effectively in a startup environment.Excellent analytical skills and ability to synthesize & communicate complex information rapidly and effectively.Location: Cambridge, MA Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.At Flagship, we recognize there is no perfect candidate. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. If you have some of the experience listed above but not all, please apply anyway. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. We collaborate, encourage failure, trust one another, and celebrate successful solutions to hard problems. Thus, we are open to all profiles with computational excellence.We are seeking the most innovative and entrepreneurial Machine Learning Scientists. Flagship has created over 100 scientific ventures resulting in >$200 billion in aggregate value, 500+ issued patents, and >50 clinical trials, spanning Moderna Therapeutics, Generate Biomedicines, Indigo Ag, Tessera Therapeutics, and others. You will join organizations at the early stages of our company creation process to develop innovative algorithmic methods, leveraging both in-house and external data to train and evaluate models while also deploying new algorithms into production and integrating deeply into experimental platforms to close feedback loops.
Head, General Manager, US Commercial Markets
Company: Amylyx
Location: Cambridge
Posted Sep 27, 2023
We do not discriminate based upon race, religion, color, national origin, gender (including pregnancy, childbirth, or related medical matters), sexual orientation, gender identity, gender expression, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. Proven track record of success in driving sales and marketing strategies within the US pharmaceutical market.Demonstrated ability to build cross-functional teams and recruit, develop, and retain top talent.Prior experience leading in a matrix environment across sales, marketing, market access, patient services/advocacy, and medical affairs to deliver results.Prior product launch experience is a must; rare disease and Neurology experience preferred. Strong preference for experience in a global organization, helping to drive the evolution of Commercial structure as pipeline expands.Solid understanding of market access and how to integrate access strategies across the US to achieve positive results.Understand the importance and impact of external key stakeholder relationships including KOL, HCP, Payers, and provide oversight of key strategies needed to ensure patient access.Demonstrated ability and desire to build a culture of cross-functional collaboration and communication, building a mindset of “if we do what’s right for patients, the profits will follow”.Operates with professionalism and sensitivity to working with people, internally and externally, from a broad range of cultures and diverse backgrounds.Must be confident and inclusive, have well-honed presentation skills and the ability to collaboratively influence peers and executive leadership. Provide oversight of field targeting, call planning/alignments, size and structure, and incentive compensation.Ensure establishment of critical KPIs in each commercial functional group. Proactively monitor metrics to identify trends and translation of trends into adjustment in strategies and tactics, share key findings having a cross-functional implication for course adjustment and alignment. Establish a close and effective collaboration with Medical Affairs to ensure field coordination and apply compliant and quality requirements to all initiatives.Collaborate seamlessly with Global Marketing, Global Patient & Professional Advocacy and Global Market Access teams to ensure alignment of and consistency with global standards.Work in partnership with Legal and Compliance, Regulatory, and other internal stakeholders to ensure tactics and operations are developed and executed in compliance with legal, regulatory, and financial guidelines.In partnership with Commercial Operations, contribute to the continued evolution of sales force systems, data, training programs, performance metricsAttract, mentor, and develop top commercial talent, nurturing a high-performing team focused on achieving ambitious goals and driving professional growthREQUIREMENTS Bachelor’s Degree required. Demonstrated ability to present at all levels including board of directors.Ability to operate effectively in a rapidly growing organization; comfortable with ambiguity and demonstrates exceptional leadership skills by confidently guiding the team through uncertain situations, maintaining a positive outlook, and fostering a collaborative and resilient atmosphere.Ability to travel at least 50%.LOCATIONThe ideal location is Cambridge, Massachusetts – candidates outside Massachusetts must be willing to travel to Cambridge on a regular basis in addition to US field travel as needed. To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn. An advanced degree in Business, MBA or similar is preferred.Minimum 20 years’ experience in progressively more senior commercial leadership in the biotechnology and pharmaceutical industry including working in a matrix organization, management of a US P&L and leadership of customer facing teams including sales and market access. This entails exceptional leadership to drive alignment and results across US Sales, Marketing, Market Access, Patient Services (ACT) and Operational teams.Fosters the Amylyx values, culture and ways of working and ensures they are embedded across the US Commercial organization. Establish appropriate sales targets and objectives, partnering with Finance and Commercial Ops on revenue projections and reporting. The ideal candidate will have a track record of prior experience as the top commercial leader launching rare disease products in the US.RESPONSIBILITIESProvide leadership, direction, and development to the US Commercial organization, establishing the vision, objectives, and strategic plan for customer-facing teams. Partner with Commercial Operations to ensure optimal business planning.