Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

MRI Technologist - FT, Weekend Incentive - Loan Assistance

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 07, 2024

Mercy is a top employer offering a variety of benefits including comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. The MRI Staff Technologist position involves operating a magnetic resonance scanner, selecting appropriate imaging techniques, and entering patient data. Mercy values compassionate care and professionalism, providing opportunities for career growth and innovation in healthcare. The Imaging Loan Repayment Assistance Program offers financial support to eligible employees.

Lead Product Manager

Company: Wells Fargo

Location: St. Louis, MO

Posted Nov 07, 2024

Wells Fargo, ranked #2 on the 2023 LinkedIn Top Companies list, is seeking a Lead Product Manager for operational insights and data optimization. The role involves leading complex initiatives, conducting market research, and overseeing risk management. The ideal candidate should have 5+ years of product management experience, strong strategic planning skills, and the ability to influence stakeholders. The position offers competitive compensation, comprehensive benefits, and opportunities for career growth.

RN - Medical Full Time Nights

Company: Mercy

Location: Springfield, Missouri

Posted Nov 07, 2024

The job posting offers a range of incentives including a sign-on bonus of up to $20,000 for experienced RNs working nights, education assistance such as loan forgiveness for new grads and tuition reimbursement, relocation assistance, and various differentials for weekend and night shifts. Benefits include comprehensive insurance, PTO, retirement funds, and opportunities for professional growth. The unit, 6B, is a telemetry unit caring for acutely ill patients with a focus on sepsis and other critical conditions.

Pharmacy Intern

Company: CVS Health

Location: St. Louis, MO

Posted Nov 07, 2024

CVS Health is offering a 3rd year pharmacy intern position with opportunities for professional growth and making a significant impact in healthcare. The role involves working closely with a licensed pharmacist, ensuring patient safety, and delivering exceptional care. Interns will lead with heart, display empathy, and collaborate to improve patient outcomes. They should possess strong communication skills, be able to lift up to 20 lbs, and have regular attendance including nights and weekends.

Registered Nurse (RN)- No NOCs! No Sundays!

Company: DaVita

Location: St. Louis, MO

Posted Nov 07, 2024

DaVita, an outpatient dialysis center, is seeking a Registered Nurse for a flexible schedule with no Sundays, on-call, or NOCs. No dialysis experience is required, as training is provided. The role involves building relationships with patients and their families, delivering care in a positive environment, and overseeing patient observations. DaVita offers comprehensive benefits, including medical, dental, vision, 401(k) match, paid time off, and more. The company is committed to diversity and belonging, ensuring equal opportunity for all candidates.

Sr Manager, QC

Company: Thermo Fisher Scientific

Location: St. Louis, MO

Posted Nov 07, 2024

Thermo Fisher Scientific is seeking a Sr. Manager - QC Analytical for their St. Louis site. The role involves managing and coordinating safety, quality, execution, and continuous improvement activities of the Quality Control Analytical departments. Key responsibilities include hiring, developing, and leading professionals within the Analytical department, ensuring compliance with Health authority regulations, and maintaining a strong Quality culture. The ideal candidate should have a Bachelor's degree, 7-10 years of experience in a regulated manufacturing, Quality, or QC laboratory environment, and 5 years of supervisory or management experience. Strong interpersonal and communication skills, along with knowledge of cGMP environment and testing principles, are required.

Occupational Therapy Assistant - COTA - Per Diem

Company: Mercy

Location: Festus, Missouri

Posted Nov 07, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a 'Top 100 Places to Work' by Modern Healthcare Magazine. The Occupational Therapist Assistant role involves assisting in patient assessments and treatment programs under licensed supervision. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They encourage applicants who embody compassion, professionalism, a positive outlook, and a strong sense of advocacy.

RN - Neurology

Company: Mercy

Location: Sappington, Missouri

Posted Nov 07, 2024

This job posting is for both new graduates and experienced RNs, offering sign-on bonuses of $5,000 for new grads and $10,000 for experienced nurses. The role is in the Neurology team, providing care for patients with conditions like stroke, seizures, and brain injuries. The schedule is 12-hour shifts, either nights or days. Benefits include loan forgiveness, tuition reimbursement, shift differentials, paid parental leave, and comprehensive health insurance. The employer values compassionate care and exceptional service, offering career growth opportunities.

RN - Med Surg 6

Company: Mercy

Location: Saint Louis, Missouri

Posted Nov 07, 2024

The job posting offers a $10,000 sign-on bonus, $2,500 incentives every 6 months, tuition reimbursement up to $2,000 annually, and up to $20,000 student loan forgiveness. It also includes shift differentials, health/dental/vision benefits, free parking, and stay pay premium eligibility. The role is part-time (24 hrs/wk) or full-time (36 hrs/wk) with 12-hour shifts, and requires working on medical-surgical units with a variety of diagnoses. The unit is the largest at Mercy Hospital, and the team collaborates to help patients recover. Qualifications include a nursing degree, RN license in Missouri, and BLS certification.

Service Specialist II - Service Division

Company: Edward Jones

Location: St. Louis, MO

Posted Nov 07, 2024

Edward Jones is seeking a Service Specialist for a full-time position. The role involves providing superior service and support to clients, branch teams, and headquarter associates. The ideal candidate will have at least 2 years of client support experience, advanced Microsoft Office skills, and the ability to work flexible hours. The company offers a comprehensive benefits package, including medical, dental, vision, disability, life insurance, a 401k plan, and paid time off. The position requires a high school diploma or equivalent, and candidates living near Tempe, AZ or St. Louis, MO home office locations are expected to work in the office three days a week.

Family Medicine Physician

Company: VillageMD

Location: Missouri City, Richmond, and Sugar Land, Texas

Posted Nov 07, 2024

VillageMD is seeking Family or Internal Medicine Physicians in Southwest Houston, Texas, including Missouri City, Richmond, and Sugar Land. The role offers supportive resources such as access to physician leaders, reduced administrative burden, highly trained support staff, optimized EMR with telehealth capability, and cross-trained care management teams. Benefits include high earning potential, comprehensive benefits package, and opportunities for professional growth. Requirements include relevant clinical experience, state license, board certification, DEA registration, Medicare/Medicaid enrollment, strong communication skills, and EMR proficiency.

RN - Telemetry- Nights

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 07, 2024

Mercy is offering a FT Night shift position for both experienced and new graduate nurses. The role requires a current RN license, Basic Life Support certification, and the ability to lift 50 pounds. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. The company values compassion, professionalism, and a positive outlook, offering opportunities for innovation and career growth.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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