Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Radiologic Tech|Flexible Schedule|FT

Company: Mercy

Location: Creve Coeur, Missouri

Posted Nov 04, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer career opportunities that align with individual skills and talents, and have been recognized as a top workplace. Mercy provides incentives such as a Loan Repayment Assistance Program up to $20,000 for Imaging co-workers. The role involves performing radiographic procedures with minimal supervision. Qualifications include a high school diploma, Radiologic Technology degree, ARRT certification, and technical skills in radiologic procedures. Mercy offers comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They foster a supportive community and encourage collaboration, with opportunities for innovation and career growth.

Occupational Therapist- Inpatient and Outpatient

Company: Mercy

Location: Troy, Missouri

Posted Nov 04, 2024

Mercy is a healthcare organization that provides compassionate care and exceptional service. They offer great benefits, including comprehensive health coverage, tuition reimbursement, and employer-matched retirement funds. The company values collaboration, professionalism, and advocacy, and encourages applicants who share these qualities to join their team.

Physician - Child Protection - Full Time Academic - SLUCare Physician Group

Company: SSM Health

Location: Saint Louis, Missouri

Posted Nov 04, 2024

Saint Louis University School of Medicine's Division of Child Protection is recruiting a full-time Child Abuse Pediatrician. The physician will join an established team in Cardinal Glennon Children's Hospital, a Level 1 Pediatric Trauma Center. Responsibilities include clinical consultation, call coverage, supervision, education, research, policy development, and community collaboration. Opportunities for academic growth, program development, and clinical research are abundant.

Nurse Practitioner (NP) Family Medicine

Company: Community Health Systems

Location: Poplar Bluff, Missouri

Posted Nov 04, 2024

Poplar Bluff Regional Medical Center is recruiting a Family Nurse Practitioner for their outpatient facility. The position offers no call duties and is open to new graduates with a license in process. Poplar Bluff is described as a clean, safe, family-friendly area with a strong public school system and a cost of living 15% lower than the US average. The city is also close to three rivers for outdoor activities and has an 18-hole golf course and country club.

Year 1 663K+ | 1:6 Call | Robotics | 4-day workweek | Sikeston, Missouri (MO)

Company: Jackson Physician Search

Location: Missouri

Posted Nov 04, 2024

Missouri Delta Medical Center is offering an OB/GYN position in Sikeston, Missouri. The role includes a 1 in 6 call rotation, a 4-day work week, and 24/7 pediatric hospitalist support. The hospital performs 450-500 births annually and can accommodate interests in Gyn/Onc with mentorship. The compensation package is highly competitive, including a base salary of $500K, sign-on bonus of $100K, relocation assistance, and student loan repayment. Sikeston is a family-friendly community with a low cost of living, located near national forests and offering outdoor activities. It's also close to major cities like St. Louis, Memphis, and Nashville.

Physical Therapist - Full Time - Flexible Schedule

Company: Mercy

Location: Springfield, Missouri

Posted Nov 04, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers tailored to individual skills and talents, with opportunities for growth and development. The role of a Physical Therapist involves planning and implementing therapy programs based on patient needs, under the supervision of a Director and Assistant Director. Mercy provides comprehensive benefits including health, vision, dental coverage, PTO, tuition reimbursement, and retirement funds. They are committed to innovation and pioneering new models of care, fostering a supportive community and positive work environment.

A Facility in Missouri Is Seeking a Otolaryngologist GMS# JOB-2995849

Company: Global Medical Staffing

Location: Missouri

Posted Nov 04, 2024

The text describes a job opportunity for a Pediatrician in Missouri, offered by a global locum tenens agency. The company, part of the CHG Healthcare family, has a history of successfully matching doctors with clients worldwide, including in the US, Australia, New Zealand, Guam, the Caribbean, Canada, China, and more. They offer competitive compensation, pre-paid travel and housing, malpractice insurance, licensing assistance, and cost reimbursement. The company prides itself on its personal service, global reach, and resources, enabling doctors to practice medicine globally and make a difference through the Making a Difference Foundation.

A MO Facility Is Seeking a Locum Tenens Otolaryngologist WBY# JOB-2995850

Company: Weatherby Healthcare

Location: Missouri

Posted Nov 04, 2024

Weatherby Healthcare offers a supportive locum tenens lifestyle for pediatricians in Missouri. They provide credentialing assistance, paid malpractice insurance, pre-paid travel and housing expenses, competitive compensation, and 24-hour access to a consultant. The company, founded in 1995, is a leading expert in locum tenens staffing for various healthcare professionals.

LPN - Medical/Surgical, Nights FT

Company: Mercy

Location: Springfield, Missouri

Posted Nov 04, 2024

Mercy is offering a full-time LPN position with no contract, working nights. New graduates and experienced LPNs are welcome, with sign-on bonuses ranging from $2,000 to $10,000 based on experience. Benefits include tuition reimbursement, employer-matched retirement funds, and comprehensive health coverage. The Surgical Trauma '3A' unit is fast-paced, focusing on adult post-operative and trauma patients with ratios of 5:1 during the day and 6:1 at night. Mercy values compassion, professionalism, and a positive outlook, encouraging collaboration and going the extra mile for excellent care.

Radiologic Technologist, Part Time, Nights

Company: Mercy

Location: Joplin, Missouri

Posted Nov 04, 2024

Mercy is a top workplace offering a range of benefits including comprehensive health coverage, tuition reimbursement, and retirement funds. They value unique individuals and provide career opportunities that align with their skills and heart. Mercy is currently hiring for a Radiologic Technologist position with exciting incentives such as a Loan Repayment Assistance Program up to $20,000 and a Sign-On Bonus of $5,000. The role involves performing radiographic procedures and requires a high school diploma, ARRT certification, and an Arkansas Radiologic Technologist License. Mercy emphasizes compassionate care, professionalism, and a positive outlook.

A Facility in Missouri Is Seeking a Locum Tenens Pulmonologist GMS# JOB-2994133

Company: Global Medical Staffing

Location: Joplin, Missouri

Posted Nov 04, 2024

The text describes a job opportunity in Pulmonology in Joplin, Missouri. The company, a global locum tenens agency, offers competitive compensation, pre-paid travel and housing, and malpractice insurance. They have a strong history of matching doctors with clients worldwide, including in Australia, New Zealand, the US, and more. The company's size allows for personalized service with global reach, backed by the resources of the CHG Healthcare family. They also support the Making a Difference Foundation, enabling physicians to help where needed, both domestically and internationally.

Anatomic Pathology Administrative Assistant

Company: Mercy

Location: Saint Louis, Missouri

Posted Nov 04, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a top workplace. The role involves clerical and administrative support, requiring excellent computer skills, Microsoft Office proficiency, and strong interpersonal abilities. Benefits include comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. Mercy encourages applicants who embody compassion, professionalism, positivity, and a strong sense of advocacy.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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