Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Neonatology Opportunity in State-of-the-Art Level III NICU

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Oct 24, 2024

Freeman Health System in Joplin, Missouri is seeking a BC/BE Neonatologist to join their established team. The position offers a competitive salary, excellent benefits, and the opportunity to supervise Neonatal Nurse Practitioners. The 24-bed Level III NICU is equipped with Ronald McDonald House and Pediatric Therapies. Teaching opportunities are available with medical students and residents. Joplin offers a high quality of life with a low cost of living, diverse medical hub, and numerous recreational activities.

Hematology Oncologist Needed in Large Missouri City With Population of 475k CPH# JOB-2993437

Company: CompHealth

Location: Springfield, Missouri

Posted Oct 24, 2024

Springfield, Missouri is a vibrant city offering a blend of urban amenities and small-town hospitality. It boasts a full range of arts, entertainment, and shopping options, along with outdoor activities in Southwest Missouri. The area is known for its lakes, rivers, state parks, and natural caves. CompHealth, a leading healthcare staffing company since 1979, is assisting with recruitment for a Hematology Oncology position. The role offers a guaranteed base salary of $600k, RVU incentives, a 4-day work week, and call of 1:9. Additional benefits include sign-on bonus, relocation assistance, fellowship stipends, and malpractice coverage. The cancer center is well-established, physician-led, and offers CME, retirement plan, life insurance, and medical benefits.

A Pulmonologist Is Needed for Locum Tenens Help in Missouri WBY# JOB-2994132

Company: Weatherby Healthcare

Location: Joplin, Missouri

Posted Oct 24, 2024

Weatherby Healthcare is offering a Pulmonary Critical Care locum tenens assignment in Joplin, Missouri. The assignment includes 12-hour shifts, 10 patients per day, and requires active state license, BC, ACLS, credentialing, DEA, and paid malpractice insurance. Weatherby Healthcare provides pre-paid travel and housing expenses, 24-hour access to a consultant, and competitive compensation. The company, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

There's So Much to Do in St. Lou

Company: Curare Physician Recruiting

Location: East Saint Louis, Illinois 62206

Posted Oct 24, 2024

The Curare Group is offering an excellent Pediatrics position in East Saint Louis, Illinois. The position is with a forward-thinking, financially strong hospital system that values teamwork, leadership, and patient care. The role is a hospital employee with outpatient call, offering a competitive annual salary, production incentives, loan forgiveness, signing bonus, relocation bonus, CME time and money, and a retirement plan. The Curare Group, a key player in the physician recruitment industry for 25 years, will guide the candidate through the job search process, from CV writing to contract negotiation, ensuring a customized job search based on lifestyle, location, and compensation requests.

Locums Opportunity in MO for Pathologist WBY# JOB-2993042

Company: Weatherby Healthcare

Location: Columbia, Missouri

Posted Oct 24, 2024

Weatherby Healthcare is offering a custom career plan in Pathology in Columbia, Missouri. The position involves 100% autopsies, requires a BC or BE license, and has specific scheduling requirements. Benefits include competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Facility in Missouri Needs a Locum Tenens Gynecologic Oncologist WBY# JOB-2994130

Company: Weatherby Healthcare

Location: Kansas City, Missouri

Posted Oct 24, 2024

Weatherby Healthcare is offering a Gynecologic Oncology locum tenens position in Kansas City, Missouri. The position involves seeing 15-20 patients per day, including 3-5 new patients, and performing normal Gyn-Onc procedures. The assignment includes credentialing, DEA, and malpractice insurance. Weatherby Healthcare provides competitive compensation, 24-hour consultant access, and online portal for time entry. The company is a charter member of NALTO and has been a leading expert in locum tenens staffing since 1995.

Pediatric Hospitalist Physician Needed in Metro Missouri CPH# JOB-2993229

Company: CompHealth

Location: Missouri

Posted Oct 24, 2024

CompHealth, a leading healthcare staffing company, offers a Pediatric Hospitalist position in Missouri. The role involves providing pediatric ED coverage, rounding on newborns, and working 12-hour shifts, day or night. The position includes NRP certification, comprehensive insurance, and retirement benefits. CompHealth assists with salary negotiation, interview coordination, license assistance, and career preference matching. The company's extensive experience and dedicated support teams ensure a smooth recruitment process.

A Locums Pulmonologist Is Wanted in Missouri CPH# JOB-2994118

Company: CompHealth

Location: Joplin, Missouri

Posted Oct 24, 2024

CompHealth, a reputable healthcare staffing company founded in 1979, offers a wide range of benefits for locums assignments. They leverage their extensive network to find the perfect assignment for the applicant. The specialty is Pulmonary Critical Care in Joplin, Missouri. CompHealth handles all details, including negotiating better pay, arranging housing and travel, providing malpractice coverage, and simplifying the credentialing process. They also offer an online portal for assignment details and time entry.

Quick access to Minneapolis - block schedule - $306k salary - $50k starting bonus

Company: Curare Physician Recruiting

Location: Saint Paul, Minnesota 55101

Posted Oct 24, 2024

A Hospitalist position is available in a growing Central Minnesota community. The role involves a block schedule primarily on day shift, with an average of 13 patients per day. The Hospitalist runs codes and procedures are not required. The compensation package is excellent, including a salary of $306,000 per year, a $50,000 starting bonus, and benefits such as paid malpractice insurance and relocation. The work-life balance is excellent, with easy access to Minneapolis and abundant outdoor activities. The schedule is 7 on, 7 off. The EMR system in use is EPIC. The Curare Group, a physician recruitment company with 25 years of experience, is facilitating the placement.

A Facility in Vermont Needs a Locums Obstetrics/Gynecologist CPH# JOB-2993735

Company: CompHealth

Location: Saint Albans City, Vermont

Posted Oct 24, 2024

CompHealth offers a wide range of locum tenens opportunities in OB/GYN, tailored to individual needs and career phases. They provide expert guidance, negotiate better pay, arrange housing and travel, and offer comprehensive malpractice coverage. Their specialized recruiters handle all details, simplifying the credentialing process. The job is located in Saint Albans City, Vermont.

Saint Louis Area Gastroenterology Job

Company: Curare Physician Recruiting

Location: St. Louis, Missouri 63101

Posted Oct 24, 2024

A well-established GI practice in Illinois, near St. Louis, Missouri, is seeking multiple Gastroenterologists. The hospital serves a population of 350,000 and offers a competitive salary, WRVU production incentives, loan forgiveness, and signing/relocation bonuses. The role involves treating various GI conditions and includes benefits like CME time, PTO, retirement plan, and access to GI tumor boards. The location offers outdoor activities, wine trails, music festivals, and international cuisine. The Curare Group, a physician recruitment specialist, is facilitating the hiring process.

Saint Louis Orthopedics Opportunity Offering Excellent Compensation

Company: Curare Physician Recruiting

Location: East Saint Louis, Illinois 62206

Posted Oct 24, 2024

A hospital system in East Saint Louis, Illinois is seeking an Orthopedic provider. The organization offers an excellent compensation and benefits package, including full benefits. The location provides a thriving arts community, excellent schools, and a high quality of life. Curare Physician Recruiting is assisting with the job search, offering support from CV writing to contract negotiation.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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