Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Outpatient-Only Opportunity for Family Medicine Providers

Company: Curare Physician Recruiting

Location: Columbia, Missouri 65201

Posted Oct 24, 2024

The text describes a job opportunity for Family Medicine providers in Columbia, Missouri. The organization offers a suburban or rural location, with physicians earning up to $350k annually in rural areas. The compensation includes a base salary, WRVU incentives, and a full benefits package. The average physician stays with the organization for 15 years, indicating job satisfaction. The role is outpatient only, Monday to Friday, with a 1:5 call ratio. The earning potential is high, with a salary range of $260-270K and potential for $450,000. Additional benefits include loan forgiveness, signing bonus, relocation bonus, CME time and money, and access to lakes for recreational activities. The company, Curare Physician Recruiting, has been in the physician recruitment industry for 25 years and offers comprehensive support throughout the job search process.

Invasive Cardiology Physician

Company: HCA

Location: Lee's Summit, Missouri 64063

Posted Oct 24, 2024

Midwest Heart and Vascular Specialists, part of HCA Midwest Health, is seeking an invasive cardiologist to join their team. The position is ideal for fellows completing in 2025, who are proficient in echo and stress test reads, and experienced in pacemaker implantation. The incentive package includes competitive compensation, a generous sign-on bonus, student loan repayment, comprehensive benefits, and CME time and dues allowances. HCA Midwest Health is Kansas City's largest network, recognized for its high-quality, compassionate care. The Kansas City region offers a thriving economy, excellent food scene, and was ranked No. 19 on Forbes' list of the 20 Happiest Cities to Work in Right Now.

General Cardiology Opportunity in Joplin, MO

Company: Archway Physician Recruitment

Location: Joplin, Missouri

Posted Oct 24, 2024

A full-time, permanent position for a non-invasive cardiologist is available in Joplin, MO. The role offers the opportunity to join a collaborative team of interventional cardiologists and cardiovascular/cardiothoracic surgeons. The practice has a comfortable call schedule covering only one hospital, with over 25,000 patient encounters in the last year. The hospital is ranked as one of the best regional hospitals for heart failure treatment and is rated among the top 100 hospitals in the nation for medical excellence and patient safety. The position offers teaching opportunities, an excellent benefits package, and a near-site day care/learning center for employees' children. Joplin, nestled in the Ozarks, offers a high quality of life with beautiful neighborhoods, ample outdoor activities, and excellent educational options. It's evolving into a thriving medical hub with a medical school and a dental school.

Electrophysiologist Is Wanted for Locums Help in Missouri CPH# JOB-2993165

Company: CompHealth

Location: St. Louis, Missouri

Posted Oct 24, 2024

CompHealth offers comprehensive services for EP Cardiology locum tenens in St. Louis, Missouri. They handle credentialing, travel, housing, and negotiate better pay, depositing it weekly. They also provide malpractice coverage and an online portal for assignment details. Their specialized recruiters manage every detail, ensuring a smooth experience.

A Facility in Missouri Is Searching for a Locum Tenens Urgent Care Physician GMS# JOB-2992712

Company: Global Medical Staffing

Location: Missouri

Posted Oct 21, 2024

The text describes a job opportunity in Urgent Care in Missouri, offered by a global locum tenens agency. The agency, part of the CHG Healthcare family, has a history of matching doctors with clients worldwide, including in Australia, New Zealand, the US, and other countries. They offer competitive compensation, pre-paid travel and housing, and malpractice insurance. The agency's global reach, personal service, and resources from the CHG Healthcare family are highlighted as advantages.

Endless Outdoor Recreation in the Ozarks

Company: Curare Physician Recruiting

Location: Springfield, Missouri 65801

Posted Oct 24, 2024

The text describes a job opportunity for a Family Medicine physician in Springfield, Missouri. The position offers a high income, a sign-on bonus, loan repayment, a 4-day work week, and a base salary of $300,000 guaranteed for 18 months. The location provides easy access to outdoor activities like golfing, hiking, and sailing. The Curare Group, a physician recruitment company, is facilitating the job search, offering support from CV writing to contract negotiation.

Emergency Medicine Advanced Practice Clinician in Birmingham, AL

Company: TeamHealth

Location: 810 Saint Vincents DrBirmingham, Alabama 35205

Posted Oct 24, 2024

TeamHealth is seeking an experienced emergency medicine physician assistant or nurse practitioner to join them at St. Vincent's Birmingham. The role is full-time, with 12 to 14 shifts per month, offering competitive rates, excellent benefits, and no overnight shifts. The hospital is a leader in the industry, providing a full range of care services, including robotic surgery, a state-of-the-art cancer center, and outstanding sub-specialty support.

PRN Emergency Medicine APP

Company: HCA

Location: Kansas City, Missouri 64131

Posted Oct 24, 2024

Research Medical Center- Brookside in Kansas City, Missouri is seeking a part-time/PRN experienced nurse practitioner or physician assistant for their Emergency Medicine department. The facility is a 511-bed Level I Trauma Center, renowned for its fast door-to-medicine time for stroke care and door-to-balloon time for heart attack care. It's the only hospital in Kansas City to be named Top Hospital and 'A' Safety grade by The Leapfrog Group. The Kansas City region offers a high quality of life with numerous corporate headquarters, a low-delay airport, and a thriving food scene. The hospital provides high-tech care in a comfortable setting, with over 700 doctors representing 29 medical specialties.

Project Management Intern

Company: IDeaS

Location: Minneapolis–Saint Paul, MN

Posted Oct 23, 2024

IDeaS is a global powerhouse of innovation and excellence, with a rich culture of creative collaboration and professional growth. The company is proud to be a global leader in revenue management solutions, with a team of passionate people who build successful careers with the company.

COTA - Home Care

Company: Centrex Rehab

Location: Minneapolis–Saint Paul, MN

Posted Oct 23, 2024

Centrex Rehab is seeking a Certified Occupational Therapy Assistant to work in home care in the Twin Cities Metro and surrounding areas. The position offers a competitive salary, flexible scheduling, and a $30,000 signing bonus. The team provides excellent support, ongoing training, and opportunities for professional growth.

Manager of Substation Engineering

Company: LUZCO Technologies LLC

Location: St. Louis, MO

Posted Oct 22, 2024

LUZCO is a woman-owned minority-owned boutique engineering firm looking for spirited candidates to join their team. They offer a range of benefits, including top-notch medical insurance, paid time off, and a relaxed work environment. The company values diversity, growth, and giving back to the community.

Sr Applied AI Researcher

Company: DataSite

Location: Minneapolis–Saint Paul, MN

Posted Oct 22, 2024

Datasite is looking for a Senior Applied AI Researcher to join their team and explore novel solutions to complex problems in the Mergers and Acquisitions space. The role involves researching solutions for improving the efficiency of traditionally slow and high-stakes workflows while maintaining customer trust.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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