Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Urgent Care Physician Is Needed for Locums Help in Missouri WBY# JOB-2992839

Company: Weatherby Healthcare

Location: St. Louis, Missouri

Posted Oct 21, 2024

Weatherby Healthcare offers a custom career plan with multiple positions available, including an Urgent Care role in St. Louis, Missouri. The job involves working with 3-5 patients per hour, performing procedures like suturing, wound care, and IV placement. Benefits include competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Facility in Missouri Seeks a Locum Tenens Urgent Care Physician WBY# JOB-2992710

Company: Weatherby Healthcare

Location: Missouri

Posted Oct 21, 2024

Weatherby Healthcare offers a supportive locum tenens lifestyle for physicians, with available dates and details upon request. The assignment involves treating acute illnesses in Urgent Care in Missouri, with 12-hour shifts and 25-45 patients per day. Benefits include competitive compensation, paid malpractice insurance, pre-paid travel and housing expenses, and 24-hour access to a consultant. Weatherby Healthcare, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals.

Senior Front-End Web Developer/Engineer -React/NextJS

Company: Integrity Web Consulting

Location: St. Louis, MO

Posted Oct 21, 2024

The company is looking for senior frontend developers to join their team of seasoned designers, developers, and web marketers. They value creative technologists who are passionate about developing highly usable and intuitive web applications. The company emphasizes the importance of integrity, humility, and a zest for life.

Surgical Advancded Practice Provider (APP)

Company: HCA

Location: Saint Petersburg, Florida 33707

Posted Oct 21, 2024

HCA Florida Pasadena Hospital is seeking a board-certified surgical PA/NP for a busy practice in St. Petersburg, FL. The position offers a competitive compensation package, full benefits, and generous PTO. The hospital, serving residents for over 50 years, provides high-quality medical care with services including ER 24/7, robotic and minimally invasive surgery, orthopedics, rehabilitation, and wound care. St. Petersburg, known for its pleasant weather and beach activities, is a growing city in the Tampa Bay area.

Wound Care - Mosaic Life Care, St. Joseph MO

Company: Mosaic Life Care

Location: Saint Joseph, Missouri

Posted Oct 20, 2024

Mosaic Life Care, a physician-led healthcare system, is seeking a board certified/board eligible Wound Care Physician. The position offers significant growth opportunities as the only wound clinic serving the region, with a diverse patient base in both urban and rural communities. The role involves clinic hours from Monday to Thursday, 8:00 AM – 4:30 PM, and Friday, 8:00 AM – 12:00 PM, with patient volumes of 10-30 per day. The physician will provide daily supervision for Hyperbaric Oxygen Therapy and perform 3,200+ minor office procedures and various OR debridements. Mosaic Life Care offers a highly competitive base salary, bonus opportunity, student loan assistance, malpractice insurance, family medical & dental insurance, life & disability insurance, 7 weeks' time off, professional dues & CME Reimbursement, 401(k) plan, relocation assistance, and onsite concierge. The physician will also be a member of the Mayo Clinic Network and participate in an onsite UMKC School of Medicine program.

Senior UI/UX Designer

Company: Integrity Web Consulting

Location: St. Louis, MO

Posted Oct 20, 2024

The company is seeking a senior digital designer with experience in UX and UI to join their team. The job requires a passion for design, strong soft skills, and expertise in various design tools and technologies. The company offers a flexible work-from-anywhere model and a strong preference for those living in St. Louis.

A Missouri Facility Is Looking for a Locums Urgent Care Physician CPH# JOB-2992711

Company: CompHealth

Location: Missouri

Posted Oct 21, 2024

CompHealth offers a wide range of locum tenens assignments, from short-term to long-term, local to distant locations. They provide expert guidance tailored to individual needs and career phases. Benefits include better pay, housing, travel arrangements, malpractice coverage, and simplified credentialing. The company specializes in urgent care and has been a leader in healthcare staffing since 1979.

Dermatologist Position in Beautiful Napa County, California CPH# JOB-2962180

Company: CompHealth

Location: Saint Helena, California

Posted Oct 21, 2024

CompHealth, a leading healthcare staffing company since 1979, offers support for dermatology professionals seeking positions in Saint Helena, California. They provide a $50k sign-on bonus and relocation assistance. The practice is physician-owned, focusing on general medical dermatology with minimal cosmetics. They offer flexible schedules and are open to providers wanting to work 0.8 FTE or less, Monday through Friday, with 36 patient-facing hours. CompHealth's services include salary and contract negotiation, interview coordination, and license assistance. Their specialized recruiters match career preferences, and experienced support teams handle all details.

Locums NP - Internal Medicine Position in MO WBY# JOB-2992644

Company: Weatherby Healthcare

Location: Ferguson, Missouri

Posted Oct 20, 2024

Weatherby Healthcare is offering a Nurse Practitioner position in Ferguson, Missouri. The role involves working with up to 12 patients per day, and includes benefits such as health, vision, dental, and 401(k) retirement plans, competitive compensation, and paid malpractice insurance. The company, founded in 1995, is a leading expert in locum tenens staffing for healthcare professionals, aiming to address challenges like physician burnout and shortages.

Flexible Part Time Remote Diagnostic Radiologist- 1st shift

Company: Envision Physician Services

Location: Saint Petersburg, Florida

Posted Oct 21, 2024

Envision Physician Services is offering a flexible part-time, fully remote opportunity for a Diagnostic Radiologist in Saint Petersburg, Florida. The compensation ranges from a minimum of $156,000.00 to a maximum of $440,000.00 annually. The role involves working as little as one week per month, with 1st shift hours from 8am-4pm. The position includes W-2 compensation at the top end of the market, a home work station, and malpractice with tail coverage. The practice is AI-enabled, ensuring efficiency with tools for consultation and communication. The company culture is described as great, with opportunities for onsite work in Florida and comprehensive support including a 24/7 call center, IT, schedulers, and CME tracking.

Midwest Metro - Easy Access to Airport - Low Cost of Living

Company: Curare Physician Recruiting

Location: Springfield, Missouri 65808

Posted Oct 21, 2024

A well-established medical practice in Springfield, Missouri, is seeking a Maternal Fetal Medicine physician. The practice has served the community for over 30 years and offers a balanced lifestyle with a 1:3 call ratio, competitive salary ($500-550K annually), loan forgiveness, signing and relocation bonuses, CME time, and malpractice coverage. The location boasts great schools, outdoor recreations, a strong economy, affordable housing, and easy airport access.

100% Remote Diagnostic Radiologist / 1st shift / Monday-Friday

Company: Envision Physician Services

Location: Saint Petersburg, Florida

Posted Oct 21, 2024

Envision Physician Services is offering a full-time remote Diagnostic Radiologist position in West Florida, with a compensation range of $550,000 to $600,000 annually. The role includes a start date bonus of $25,000, annual retention bonus, productivity bonus, flexible schedule, leadership development opportunities, comprehensive benefits, and malpractice coverage. The position requires board certification or eligibility, proficiency in general diagnostic readings across modalities, and rotating weekend coverage.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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