Jobs at Click Therapeutics
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Senior Research Associate, Bioanalytical
Company: Kisbee Therapeutics
Location: Cambridge
Posted Dec 13, 2023
Job Type: Full-time Salary: Commensurate with role and experience Kisbee Therapeutics is an Equal Opportunity Employer and does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other characteristic protected by applicable law. in Biology, Bioengineering, Biochemistry, or related field with 3+ years of biotech/pharma industry experience Strong assay development and troubleshooting experience, including LLOQ optimization and non-specific binding matrix effects Experience with MSD, Quanterix, rtPCR instrumentation is a plus Exhibit independence, enthusiasm, openness, and adaptability MSD workbench, softMAX pro, Watson LIMS, JMP, Graphpad Prism preferred Attention to detail and strong communication skills are required Ability and desire to work in a collaborative environment Passion for curing neurodegenerative diseases is a plus The candidate must thrive in a fast-paced, dynamic environment with high expectations Integrity, quality, ability to troubleshoot issues, creative, bold, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values at Kisbee At Kisbee, we believe that great teams are built on a foundation of kindness, honesty, and balance. Join us, and together we will redefine the way we treat neurodegenerative disease. New ideas and innovation fuel us, science and data guide us, and novel challenges and opportunities bring out our best. Key Responsibilities Development of bioanalytical and biomarker ligand-binding assays, including processing and analysis of large molecules (proteins, mRNA, etc.). or B.S. ELISA, ECL detection, Quanterix) in biological matrix (plasma, serum, CSF, tissue lysate) to measure compound concentration, detect the presence of anti-drug antibody and neutralizing anti product antibody activity. This role will primarily support the execution of LBA assays in supporting of our nonclinical and clinical studies Work closely with other departments to establish the timelines of each project Independently plan, execute, and report routine sample analysis within group timelines Monitor and review data, qualification plans and reports, and bioanalytical plans and reports internally as well as outsourced to CRO’s Ensure data and documentation quality Experience and Qualifications M.S. Position SummaryWe are seeking a technical biomarker/bioanalytical scientist who has strong experience with the development and validation of biomarker, cell-based, immunogenicity, immuno- enzymatic, and/or chromatographic assays for support of preclinical, clinical and product release studies. We work hard but recognize that we all have lives outside the lab and office.
Director/Senior Director CMC
Company: MOMA Therapeutics
Location: Cambridge
Posted Dec 09, 2023
or equivalent) in chemistry, pharmaceutical sciences or a relevant discipline You work hard, you are kind to others, and you enjoy being a part of a collaborative team that gets stuff done in an environment where scientific data rules the day MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. Your ability to build relationships, both internally and externally, and operate in a lean environment will enable success for you and our programs. You will lead multi-disciplinary CMC teams through preclinical development, IND filings and into clinical development. MOMA’s development programs require independence and leadership in a highly dynamic environment. In this role you will… Lead small molecule CMC teams comprised of technical leads and key stakeholders Establish CMC program strategy, including key activities, timelines, and budgets, in collaboration with technical experts on your team Oversee the execution of CMC-related development and manufacturing activities at external manufacturing partners, including technology transfer and on-site management Guide the authoring of regulatory filings in terms of substance and scope Identify CMC program risks and work with the CMC team to develop contingency plans Represent the CMC function at the program level and collaborate to develop program strategies Forge close working relationships across disciplines and with external partners and consultants to advance programs through clinical development About you… You have at least 10 years of experience in small molecule CMC, including experience in an early-stage biotechnology company You have experience effectively collaborating with and managing CDMOs You have experience authoring regulatory filings including INDs You are familiar with solid oral dosage form development You have a working knowledge of regulations and guidelines for small molecule development You’ve led teams and/or projects in a dynamic fast paced environment You have explicit achievements that indicate your effectiveness You’re organized and have excellent written and verbal communication skills You understand relationships are the key component of achieving significant results You know how to make decisions independently Subject matter expertise in Drug Product or Analytical method development is a plus You have an advanced degree (MS/Ph.D. In this role, you will lead drug substance, drug product and analytical development activities, and ensure the delivery of clinical trial supplies across two small molecule programs as they enter clinical development. You will manage CMC program timelines toward key goals and maintain budget oversight for all CMC activities. Your deep technical background, combined with leadership and an ability solve scientific problems under pressure will be fundamental to operating in this role. You will collaborate with internal functions to plan and align on key objectives as development unfolds. You will partner with external organizations and consultants to execute strategically efficient development and manufacturing with an eye toward regulatory milestones.
Manager/Senior Manager, People Experience
Company: LEXEO Therapeutics
Location: New York City, NY
Posted Dec 13, 2023
Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment. Primary Responsibilities Partner with the Vice President, People Experience and stakeholders to develop and improve key people strategies and processes Develop and oversee the talent onboarding process, including authoring or updating underlying programs, improving data management, record-keeping and analysis in Lexeo’s HRIS and payroll system, and leading associated events and activities (e.g., orientations, and engagement projects) to foster an informed and motivated employee base Provide talent acquisition and applicant tracking support as needed Partner with the VP on performance management, compensation and benefits administration, and goal setting processes to keep Lexeo well-balanced and aligned between corporate priorities and employee objectives Manage the supporting processes that drive the employee lifecycle and serve as the primary administrator for all HR systems Maintain the integrity of the HRIS and employee records to ensure consistency and compliance Work closely with Finance on payroll, equity administration, contractor management, etc. Operate as a key champion, driver and model of Lexeo’s culture Provide support on ad-hoc people operations initiatives and projects as needed Required Skills & Qualifications Bachelor’s degree preferred 5+ years experience in human resources with a focus on operations High level of literacy in the Microsoft suite of cloud-based productivity tools Experience working with a PEO in an administrative capacity; experience with JustWorks preferred Familiarity with CultureAmp, JustWorks, and Egnyte strongly preferred Experience in emerging growth biotech companies preferred Benefits administration and compensation experience are strong pluses Exceptional prioritization, organization, problem-solving, collaboration and communication skills Ability to maintain a high level of discretion and confidentiality Ability to pivot between tactical and strategic work Employee focus and customer service mindset Depending on qualifications and overall experience, base salary is likely to be $135,000 - $175,000 per year. The incumbent will report to the Vice President, People Experience. A remote arrangement may be considered for exceptional candidates. Manager, People Experience will serve as the operations lead for the People Experience team, take on special projects and partner with business stakeholders on people-related needs. Location Our work culture is a hybrid model with days in the New York City office and days working from home. Leading with a solutions-oriented service mindset, this individual will be charged with ensuring that the entire Lexeo staff is focused on achieving monumental goals by building and maintaining a best-in-class people operations infrastructure. Role Summary The Manager/Sr.
Data Scientist/Sr. Data Scientist
Company: Scribe Therapeutics
Location: East Bay
Posted Dec 08, 2023
All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, disability, age, or veteran status. The offered pay range will depend on internal equity and the candidate’s relevant skills, experience, qualifications, training, and market data. Preferred Skills and Background: PhD in Computer Science, Data Science, Applied Mathematics, Statistics, Computation Biology or equivalent engineering fields. Hands-on experience in ML/AI-based protein modeling, including familiarity with AlphaFold2, RoseTTAFold, ESM2, and similar technologies. Preferred experience with analytics engines and data systems designed for processing large-scale data, such as SPARK, Databricks, AWS EMR, Snowflake, and data lakes. Proficiency in utilizing various tools and frameworks for machine learning and data science, such as PyTorch, Scikit-Learn, Tensorflow, Keras, AWS SageMaker, and others. We will provide an intellectually stimulating, collegial and fast-paced environment. Excellent communication and collaboration skills, enabling effective interaction with internal software and data science teams, external IT contractors, and cross-functional teams. Strong background in genomics ML/AI modeling, with practical knowledge of engineering genetics and epigenetics features and advanced DL algorithms and architectures, such as CNN, transformer, Graph Attention Network, Large language model, and similar technologies. Foster a driven, fast-paced, dynamic, and fun environment in which to do rigorous science.
Region Manager, Southwest
Company: Corcept Therapeutics
Location: Peninsula
Posted Dec 10, 2023
If you are based in California, we encourage you to read this important information for California residents linked here. Please visit our website at: https://www.corcept.com/ Corcept is an Equal Opportunity Employer Responsibilities: Formulate sales strategies and analyze performance within the region Fully engage with key customers by developing and implementing strategies that support sales growth Provide on-going coaching and development of CSS team Develop and maintain customer relationships with key executives and decision makers in all key accounts Participate in and contribute to commercial team planning sessions as requested, representing the needs of customers and the sales team and driving business building plans of the organization Act as local liaison and collaborator, building consensus on strategies and tactics that drive business results Operate within compliance guidelines at all times Preferred Skills, Qualifications and Technical Proficiencies: Proven success in leading a sales team within a large geography Experience in endocrinology, orphan disease, or other specialized markets a plus Strong clinical acumen Ability to analyze sales and other relevant market data to formulate strategic plans Strong ability to collaborate and work cross-functionally Required to travel by car and plane at least 80% of the time Preferred Education and Experience: Must maintain a driving record in accordance with Corcept vehicle policy Master’s Degree in a life science or related field or equivalent experience The pay range that the Company reasonably expects to pay for this position is $190,000 - $215,000; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education. Today, we have a unique opportunity to revolutionize the treatment of severe endocrine, oncology, metabolism and neurology disorders and aim to deliver better outcomes for the people affected by them. Our work has uncovered over 1000 proprietary selective cortisol modulators, including our marketed product, Korlym® (mifepristone), the first treatment available for those living with Cushing’s syndrome, a life-threatening condition caused by excess cortisol activity. Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs. LI-Remote Applicants must be currently authorized to work in the United States on a full-time basis. The RM will manage a team of Clinical Specialists (CS) and provide consistent direction regarding the execution of sales and marketing strategies for the Southwest region. Our vibrant community is made up of over 300 people—medical practitioners, scientists, and industry professionals—all with the shared goal of advancing the science of cortisol modulation to treat serious disease. That is why for twenty-five years we have pushed the boundaries of what is possible, driven by fiercely independent science, open collaboration and the curiosity to follow the data wherever it leads.
Scientist l, Protein Expression
Company: Nutcracker Therapeutics
Location: Other US Location
Posted Dec 09, 2023
Nutcracker Therapeutics is an equal opportunity employer and values diversity, as such, we do not unlawfully discriminate on the basis of race, color, religion, citizenship, political activity or affiliation, marital status, age, national origin, ancestry, physical or mental disability, medical condition (as defined under California law), veteran status, sexual orientation, gender identity, gender expression, sex or gender (which includes pregnancy, childbirth, breastfeeding, or related medical conditions), taking or requesting statutorily protected leave, or any other basis protected by law. Any unsolicited resumes, including those submitted to hiring managers, are deemed to be the property of Nutcracker. Employees are also eligible to participate in benefits including Medical, Dental, Vision, Life Insurance, 401(k), PTO plan and employee stock options. Recruiters, agencies and other persons need to have written agreement with Nutcracker, and written approval from a Nutcracker Human Resources representative, to submit resumes for a specific position in order to receive credit. Agency Disclaimer: Nutcracker Therapeutics, Inc. (hereafter, Nutcracker) does not accept unsolicited resumes from recruiters or employment agencies in response to the Nutcracker Careers page or a Nutcracker social media post. The incumbent will perform cell culture experiments, transient transfection, expression and purification of various protein formats such as antibodies, multispecifics, fusion proteins, and enzymes. If you are driven to discover, create, and inspire something that moves science and technology forward, and lasts a lifetime and beyond, you’re ready to be a Nutcracker. Responsibilities: Transient transfection and expression of engineered protein at scales ranging from 0.5mL to >100mL using Expi293 cells Develop and execute protein production workflow for transfection, expression, purification, and protein characterization Support protein engineering, enzyme therapeutics, and in vivo expressed biologics pipeline projects Participate and contribute in cross-functional project teams and platform developments Requirements: PhD (with at least 3 years’ of postdoc and industrial experience) or BS/MS (with 5 years’ academic/industrial experience) in biochemistry/cell biology or equivalence Able to perform and trouble-shoot problems with protein production (transfection/expression/purification) and characterization with minimum supervision Deep understanding of both DNA and RNA transient transfection and protein expression techniques Basic operational knowledge of AKTA purification and automation system Familiarity with bispecific/multispecific antibody production and characterization Perform protein titer assay such as ELISA and/or quantitative WB (Protein Simple JESS) Excellent organizational, technical, and troubleshooting skills with attention to detail Work independently as well as collaboratively as a part of the project team Great team player with a can-do attitude and the desire to excel in a fast-paced environment The expected salary range for the Scientist l, Protein Expression is $120,000 to $130,000, based on candidate experience, education, location, and other job-related factors. If your best work is performed in a fast-paced entrepreneurial work environment where meaningful work is mastered each day, we’d love to hear from you. Nutcracker explicitly reserves the right to hire said candidate(s) without any financial or other obligation to the recruiter or agency.
Associate Director, QA Operations
Company: Corcept Therapeutics
Location: Peninsula
Posted Dec 12, 2023
Proficient computer skills are needed with experience using Microsoft Word, Excel, PowerPoint, and Visio. Thorough knowledge of 21 CFR 210/211 global cGMP regulations, and ICH guidelines regarding good manufacturing practices in the development, manufacturing, testing, delivery, and control of pharmaceutical products. The pay range that the Company reasonably expects to pay for this headquarters-based position is $175,000 - $207,000; the pay ultimately offered may vary based on legitimate considerations, including geographic location, job-related knowledge, skills, experience, and education. Ability to author, review, and approve SOPs and other controlled documentation for compliance with applicable regulations. Ability to lead or support internal and external compliance audits of suppliers, CLOs, and CMOs. Travel required Preferred Education and Experience: Bachelors or Masters degree in a chemistry, biology, engineering or related field. Lead and support Contract Service Provider (CSP) qualification audits that can include contract manufacturers, contract testing organizations, distribution depots, PV service provider, and pharmacy. Generate, review, and negotiate Quality and Technical Agreements with Contract Service Providers (CSP). Review and approval of validation protocols and reports (e.g., process, method, etc.). 12+ years’ experience in bio/pharmaceutical industry including 7+ years in Quality Assurance.
Region Manager, Southwest
Company: Corcept Therapeutics
Location: Peninsula
Posted Dec 10, 2023
An annual cash bonus and equity grants may be provided as part of the overall compensation package, in addition to a full range of medical, financial, and other wellness benefits, dependent on the position offered. If you are based in California, we encourage you to read this important information for California residents linked here. Please visit our website at: https://www.corcept.com/ Corcept is an Equal Opportunity Employer Today, we have a unique opportunity to revolutionize the treatment of severe endocrine, oncology, metabolism and neurology disorders and aim to deliver better outcomes for the people affected by them. Responsibilities: Formulate sales strategies and analyze performance within the region Fully engage with key customers by developing and implementing strategies that support sales growth Provide on-going coaching and development of CSS team Develop and maintain customer relationships with key executives and decision makers in all key accounts Participate in and contribute to commercial team planning sessions as requested, representing the needs of customers and the sales team and driving business building plans of the organization Act as local liaison and collaborator, building consensus on strategies and tactics that drive business results Operate within compliance guidelines at all times Preferred Skills, Qualifications and Technical Proficiencies: Proven success in leading a sales team within a large geography Experience in endocrinology, orphan disease, or other specialized markets a plus Strong clinical acumen Ability to analyze sales and other relevant market data to formulate strategic plans Strong ability to collaborate and work cross-functionally Required to travel by car and plane at least 80% of the time Preferred Education and Experience: Must maintain a driving record in accordance with Corcept vehicle policy Master’s Degree in a life science or related field or equivalent experience The pay range that the Company reasonably expects to pay for this position is $190,000 - $215,000; the pay ultimately offered may vary based on legitimate considerations, including job-related knowledge, skills, experience, and education. Our work has uncovered over 1000 proprietary selective cortisol modulators, including our marketed product, Korlym® (mifepristone), the first treatment available for those living with Cushing’s syndrome, a life-threatening condition caused by excess cortisol activity. Corcept appreciates the commitment and hard work of all our team members as we strive to discover and develop novel treatments for patients with serious unmet medical needs. LI-Remote Applicants must be currently authorized to work in the United States on a full-time basis. The RM will manage a team of Clinical Specialists (CS) and provide consistent direction regarding the execution of sales and marketing strategies for the Southwest region. Our vibrant community is made up of over 300 people—medical practitioners, scientists, and industry professionals—all with the shared goal of advancing the science of cortisol modulation to treat serious disease.
Sr. Scientist/Principal Scientist, Computational Chemistry
Company: MOMA Therapeutics
Location: Cambridge
Posted Dec 11, 2023
MOMA Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. You work hard, you are kind to others, and you enjoy being a part of a collaborative team that gets stuff done. Proficient in scientific programming and tool development with Python You have demonstrated understanding of all aspects of modern drug discovery including medicinal chemistry, DMPK principles, multi-parameter optimization. In-depth knowledge of quantum mechanics, QM/MM and modeling protein-protein interactions is highly preferred. You have deep experience implementing computational chemistry strategies across all stages of drug discovery including target identification, hit identification and optimization to achieve program goals. About you... You have a PhD degree in computer science, computational chemistry, or related fields with 2+ years relevant drug discovery experience in a pharmaceutical or biotechnology setting. Level will reflect experience. Provide computational chemistry solution to drug discovery programs including building and deploying tools and analyses that impact medicinal chemistry decisions on drug discovery projects, spanning target assessment, hit finding, and lead optimization. You enjoy being in an environment where scientific data rules the day. Collaborate closely with drug discovery team and other computational scientists to strategize what data to collect to populate the KnowledgeBase, address computational/informatic needs.
Support Operations Manager
Company: Force Therapeutics
Location: Remote
Posted Dec 13, 2023
We base all employment decisions on merit, qualifications, and business needs, without regard to race, color, religion, belief, national or social origin, sex, age, physical or sensory disability, HIV status, sexual orientation, gender identity/expression, marital status, military service, or any other protected status. Generous PTO: Ample vacation time, unlimited safe and sick time, volunteer time off, and extra holidays, so that you take the time you need. Our intention is to provide equal opportunities, eliminate pay gaps, and maintain competitive salaries benchmarked against industry standards. At Force Therapeutics, the well-being and growth of our team members comes first. The base salary range for this role is : $95,000 - $105,000 per annum* *Salaries are determined based on qualifications, experience, and other relevant factors. Pay Transparency Notice At Force Therapeutics, we prioritize transparency and fairness in all aspects of our business, including the way in which we compensate our people. Summer Fridays: A nod to work-life balance, ensuring you get the most out of those sunny summer days. We proudly encourage candidates of diverse backgrounds and experiences to apply. We do not use social media platforms or personal messaging apps for job postings. To ensure that all candidates and employees understand our compensation structure, we provide clarity on pay ranges for each role.
IT Network Engineer
Company: Shape Therapeutics
Location: Seattle, WA
Posted Dec 08, 2023
Experience with administering one or more of the following is preferred; Windows Active Directory, Google Workplace, Microsoft 365 (O365), databases, JAMF, Intune, Okta, VMware, anti-malware (Cortex XDR), certificates, RADIUS, etc. Experience with two or more of; macOS, Windows 10/11, Windows Server, and/or Linux, is preferred. Assist with the ongoing management and administration of one or more of; Windows Active Directory, Google Workplace, Microsoft 365 (O365), databases, Jamf, Intune, Okta, VMware, anti-malware (Cortex XDR), certificates, RADIUS, and more. Configure and install various network devices, including routers, switches, firewalls, load balancers, and wireless access points. Implement and maintain network security measures, including firewalls, intrusion detection systems, endpoint protection tools, and virtual private networks (VPNs), to protect the organization's data, people, and systems. Additional compensation may include annual target bonus and/or sign-on bonus, equity grant and relocation bonus. Document network configurations, procedures, and troubleshooting steps to maintain an up-to-date network infrastructure knowledge base. What you Bring Bachelor's degree (or equivalent experience) in Information Systems, Computer Science, Computer Engineering, Information Security, or similar technical or engineering experience in a relevant field or discipline. We are proud to offer a competitive paid parental leave benefit, an annual employee stipend for employees to use however they choose, a Flex Paid Time Off program (allowing flexible PTO for vacation, sick leave, and other purposes) and Company paid Long Term Disability. Experience navigating AWS networking preferred.
Director, Senior Director Genome Engineering (Vector Genome)
Company: Voyager Therapeutics
Location: Cambridge
Posted Dec 12, 2023
Sophisticated scientific management skills and business judgment with an ability to evaluate alternatives, establish priorities, and apply resources effectively. Must be highly motivated, and will derive motivation from working in a small, entrepreneurial biotech environment, accepting the challenge of broad responsibilities and opportunities within a fast-paced, matrix-focused can-do culture. Must have intellectual and scientific curiosity and integrity; must be scientifically rigorous and creative; committed to patient-centricity, transparency, and ethical research values. Can-do team-oriented attitude which is consistent with Voyager core values. Qualifications A Ph.D. or MD/Ph.D. Enthusiasm for operating effectively within an entrepreneurial and science-driven company environment. Track record of driving innovative ways of thinking and/or innovative ways of using data. Participate in the process of selecting, prioritizing, and accelerating the development of assets. Support the continued protection, creation, and expansion of the company’s intellectual property. Responsible for interrogation of candidate sequences, and reduction-to-practice of sequences intended for clinical application, for numerous gene therapy initiatives.