Be Or Bc Jobs in Cambridge
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QA Coordinator
Company: TreeHouse Foods
Location: Cambridge
Posted Aug 05, 2023
TreeHouse Use Only: IND1 About You: You'll fit right in if you have: A great attitude and willingness to learn and grow in the roleExcellent verbal and written communication skillsAbility to organize and prioritize tasks to meet deadlines.Self-motivated with strong multitasking, analytical thinking, and problem-solving. Your TreeHouse Foods Career is Just a Click Away! What You Gain: Competitive compensation and benefits programEnrollment in our wellness and employee assistance programsPaid holidays, vacation, and other competitive paid time off opportunitiesAn inclusive working environment where you can build meaningful work relationships with a diverse group of people Leaders who are invested in supporting your career growthOpportunities to be recognized for outstanding contributions to your team through our employee recognition programs Job Description: You'll add value to this role by performing various functions including, but not limited to: PDM Task - oversee all PDM tasks that fall under the Quality Assurance part of said taskSpecifications - Oversees all internal specifications while maintaining and updating the specs as needed based on production scheduling or customer updates.Customer Samples - handles all customer samples that need to be shipped, also coordinates with Scheduling, Production, and QA techs to make sure samples are pulled as requested.Purchase Requisitions - handles all purchase requisitions for items that are ordered within the QA and Sanitation departments.Purchase order receipts - handles all documentation and makes sure all receipts are logged in the systemDeveloping and Managing KPI reports and analyzing/trending data to assist the department in decisionsAssisting with IQS implementation and tracking within the departmentSorting and filing through daily paperwork, dump sheets, out-of-spec reportsHelps with Micro Data and Enviromap reporting within the department Important Details: This is a full-time on-site role working a Monday through Friday schedule. Click on the "Apply" button or go directly to www.treehousefoods.com/careers to let us know you're ready to join our team! We are investing in talent and creating a performance-based culture where employees can do their best work, directly impacting our mission to make high quality, affordable food for our customers, communities and families. Typical business hours are 8 am to 5 pm with the need to be flexible based on departments and facility needs. At TreeHouse Foods, our commitment to excellence extends beyond our products and revolves around our people. We hope you will consider joining the team and being part of our future. Employee Type: Full time Location: MD Cambridge Job Type: Quality Job Posting Title: QA Coordinator About Us: TreeHouse Foods (NYSE: THS) is a leading manufacturer of private label packaged foods and beverages, operating a network of production facilities across the United States and Canada.
Associate Scientist I/II, Process Sciences
Company: Vor Bio
Location: Cambridge
Posted Aug 03, 2023
Vor Bio is seeking a highly motivated Associate Scientist I/II to join the Process Science Team. The successful candidate will have a background in cell/molecular biology, bioengineering, or immunology with experience working with mammalian cell cultures. The role involves establishing the base CAR-T process, evaluating CART phenotype and functionality, and improving the CAR-T platform. The successful candidate will have the opportunity to work in a highly collaborative team in a startup environment.
Scientist / Senior Scientist, Bioanalytical (DMPK)
Company: Generation Bio
Location: Cambridge
Posted Aug 05, 2023
We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Significant cross functional interactions are expected with key partnership between Pharmacology, Toxicology, and other departments.RESPONSIBILITIES:Design, optimize, and execute assays to assess drug concentration in in vitro and in vivo samples, in various biological matricesBuild in-house LC-MS/MS bioanalytical capacityEmploy cutting edge technologies to understand pharmacokinetics and biodistribution attributes of this exciting new modalityScientific oversight of CRO activities for outsourced studies including method transfer, data quality and analysisDesign experiments, analyze data & interpret resultsSummarize studies in high quality written reports and oral presentationsQUALIFICATIONS:PhD degree in related field, or Masters degree with minimum of 8 years of related experience, or Bachelor’s degree with minimum of 10 years of experience in Bioanalytics or related disciplineExperience in developing LC_MS/MS based quantitative assays requiredExcellent lab-based skills and the ability to work independently to analyze, interpret, and present data requiredBiotech and/or pharmaceutical industry experience requiredDemonstrated leadership and hands on experience in bioanalytical assay development, study execution, data analysis and reporting in a regulated environment preferredExcellent knowledge of bioanalytical guidance and direct experience with IND, NDA, BLA, MAA submission preferredAbility to multi-task to support multiple projects across platformAbility to work in matrixed environmentOrganized, excellent communication skills, highly collaborative, team player mindsetPOSITION: Full-Time, ExemptEEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. The job responsibilities include working closely with CRO’s to transfer assays, provide scientific oversight for externally sourced studies, as well as ensure seamless execution in collaboration with our Operations team. The primary job responsibilities include LC-MS/MS based bioanalytical method development, sample analysis in various biological matrices, data analysis and reporting. This individual will create bioanalysis capacity in the department by training DMPK members and through the identification, development, and management of CRO relationships. This is a significant opportunity to build the required in-house capability and the candidate is expected to be an independent thinker, a self-starter, and someone who is skilled at working across functions. To see additional roles, please also check out https://generationbio.com/careers/ SUMMARY: Generation Bio is seeking a highly motivated, energetic and enthusiastic scientist/sr. RES has the potential to expand Generation Bio’s manufacturing scale to hundreds of millions of doses to support its mission to extend the reach of genetic medicine to more people, living with more diseases, around the world.We are a thriving, collaborative, creative community of 165 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts. Delve further. Please visit www.generationbio.com or follow @generationbio. The platform is designed to enable multi-year durability from a single dose, to deliver large genetic payloads, including multiple genes, to specific tissues, and to allow titration and redosing to adjust or extend expression levels in each patient.
Head of Sustainability
Company: Inari
Location: Cambridge
Posted Aug 05, 2023
Any discrepancies or inaccuracies found during the background check may impact your candidacy for the position. As a thought leader, this role is an opportunity to shape the sustainability dialogs to motivate, inspire and provoke (as appropriate) external stakeholders from the perspectives of food system. The Head of Sustainability will be an active member of the senior leadership group, permanent invitee to the corporate ESG board committee, and regularly engaging with the Executive Leadership Team and board members. The individual will be a key member of the Corporate Affairs function and its leadership team.RESPONSIBILITIESInternal and external engagementBe the primary management contact for the ESG board committee including working with the chair on agenda, materials, and follow-through. Serve as a thought leader internally and externally to help shape Inari’s sustainability message with employees, customers, partners and NGOs, with the ability to distill and effectively communicate highly complex information.Cultivate a grassroots culture of sustainability up and down the organization.Overall strategy and planDevelop, recommend, and drive the implementation of the organization’s sustainability strategy and policies – executing plans by closely working with and through all functions.Manage value creation through high impact initiatives across the organization, embedding measurement and reporting mechanisms.Own SEEDesignTM System Modeling (Inari’s customized dynamic system models) and help guide the tradeoff dialogues while driving Product Stage Gate applications.Overall execution Deliver timely, accurate, and effective sustainability reports by closely working with related functions.SKILLS AND QUALIFICATIONSSkillsStrategic development and executionSubstantive experience in building comprehensive strategies and the drive to execute results with willingness to be bold and forward looking. Sustainability knowledge and skillsAn inherent understanding of the role sustainability plays across all aspects of today's business environment from strategy to operations, and the management of external stakeholders.Demonstrated passion for sustainability with a strong interest in building a more sustainable and nature-positive food system.AnalyticalWill need to get adept with Inari’s custom dynamic system model – the SEEDesignTM System Model – and champion the work internally and externally. Excellence in tracking, reporting, and interpreting of a wide range of data and systems.Mobilization and inspirationExcellent communication and presentation skills along with the ability to inspire large groups of both internal and external stakeholders.Clear passion for sustainability and the value it can bring – thriving in an inclusive culture driven by innovative technology.Interpersonal Collaborative across boundaries and learning mindset.Qualifications8+ years of experience in strategy, sustainability, or similar roles; at least 5+ years of direct sustainability experience.MBA or similar advanced professional degree preferred.Experience working in the food & agricultural value chain.FOR U.S. And we've intentionally combined experience with potential, bringing agriculture industry experts with the desire to innovate together with bright minds from academia, human therapeutics, software, and consulting. To ensure an efficient and accurate background verification, we kindly ask that you carefully review and accurately represent your work history, education and other relevant information on your resume. We’ve deliberately built a team that brings diversity of thought to all aspects of our business, to generate new ideas, approaches, and ways of operating. CANDIDATES: Please note that we use the resume you submit with your application during our background check process. If you want to be part of a diverse and inclusive team developing unique solutions to feed the world while protecting our planet’s natural resources, we’d love to hear from you!In this role, the Head of Sustainability will be responsible for developing and recommending sustainability strategies along with implementation and monitoring of plans, targets, and metrics for the company from Scopes 1 through 4. This individual will internally champion and work across the organization to ensure timely execution of projects and initiatives. The results will lead to more productive acres delivering value creation for farmers and a more sustainable future for our planet.Our success is dependent on great minds, collaborating to generate bright ideas and deliver exceptional outcomes.We have over 270 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), as well as a product development site in West Lafayette, IN (USA). Through our unrivaled technology platform, Inari uses predictive design and advanced multiplex gene editing to develop step-change products. About Inari...Inari is the SEEDesign™ company.
Scientist - GMP
Company: Thermo Fisher Scientific
Location: Cambridge
Posted Aug 09, 2023
In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role. Working Environment: PPD, part of Thermo Fisher Scientific values the health and well-being of our employees. To learn how PPD, part of Thermo Fisher Scientific can advance your career, apply now! At PPD, part of Thermo Fisher Scientific we hire the best, develop ourselves and each other, and recognize the power of being one team. Education and Experience: Bachelor's degree or equivalent and relevant formal academic / vocational qualificationPrevious industry experience (0-2+ years) that provides the knowledge, skills, and abilities to perform the job. Essential Functions: Provide testing support for the Pneumo programs.Perform testing in a GMP lab and follow all applicable SOPs and STMs when performing the tests.Perform colorimetric 96-well plate-based tests such as anthrone, uronic acid, BCA, biotin, free polysaccharide.Perform HPLC and SEC-MALS analysis.Participate in the method qualification, validation, transfer as necessary.Perform trending of QC assays, reagents, assay controls, system suitability, standards.Perform release and stability testing.Support the SAP implementation in the Binney street QC.Participate in the qualification and management of critical reagents, reference standards.Assist in preparing SOP's, technical protocols, reports, OOS/OOT/deviation investigations.Work with QC management in data analysis, peer review of analytical data.Work with the QC team to maintain and update inventories.Monitor controlled temperature units. Below is listed the working environment/requirements for this role: Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.Able to work upright and stationary and/or standing for typical working hours.Able to lift and move objects up to 25 pounds.Able to work in non-traditional work environments.Able to use and learn standard office equipment and technology with proficiency.May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment. Our 4i Values: Integrity - Innovation - Intensity - Involvement If you resonate with our 4i values above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world's most urgent health needs, submit your application - we'd love to hear from you! Responsible for review and compilation of results and data comparison against SOP acceptance criteria, methodology, protocol, and product specifications. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees.
R&D Scientist
Company: Generation Bio
Location: Cambridge
Posted Aug 02, 2023
We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race (to include traits historically associated with race including, but not limited to, hair texture, hair type, hair length, and protective hairstyles such as braids, locks, twists, hair coverings, and Bantu knots), color, gender, religion, national origin, gender identity, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Generation Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. To see additional roles, please also check out https://generationbio.com/careers/ Job Location: 301 Binney Street, Suite 401, Cambridge, MA 02142 (Telecommuting is available up to one day per week)Approximately 10% domestic and approximately 10% international travel required.This position qualifies for Generation Bio Co.’s employee referral incentive program.The R&D Scientists will be responsible for the following duties:Lead, design, and execute laboratory experiments to develop the manufacturing process for pharmaceutical substances used in gene therapy treatments;Perform in-house experiments and supervise efforts related to the purification process development;Perform experiments and collaborate efforts related to the development of process steps including cell lysis, enzyme-based synthesis of DNA drugs, chemical precipitation, depth filtration, tangential flow filtration, sterile filtration, viral filtration, and column chromatography;Perform testing and analysis of process intermediates and final drug substance;Lead tech transfer of small-scale process(es) to the MST (Manufacturing science and technology) and GMP groups for large scale manufacturing at contract manufacturing organization (CMO);Provide technical resources for recent technologies in drug development;Write and review protocols, reports, and manufacturing batch records; andPrepare, analyze, and present data to cross functional teams.Job Requirements:Employer requires a Master’s degree in Pharmaceutical Sciences, Biotechnology, Bioengineering, or closely related field and at least two (2) years of work experience as a Research Scientist (or related occupation) performing downstream process development in a pharmaceutical manufacturing or industrial environment.In addition, the employer requires the following:Demonstrated ability testing and analyzing process intermediate and final drug substance samples gained through two (2) years of work experience;Demonstrated ability designing, executing, and troubleshooting experiments to develop downstream processes for the purification of drugs gained through two (2) years of work experience;Demonstrated ability authoring and executing protocols, interpretating data, and generating final reports gained through two (2) years of work experience; andDemonstrated ability optimizing scalable purification processes and manufacturing activities in a GMP environment gained through one (1) year of work experience.All years of experience may be gained concurrently.EEOC Statement: Generation Bio believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. RES has the potential to expand Generation Bio’s manufacturing scale to hundreds of millions of doses to support its mission to extend the reach of genetic medicine to more people, living with more diseases, around the world.We are a thriving, collaborative, creative community of 165 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts. Delve further. Please visit www.generationbio.com or follow @generationbio. The platform is designed to enable multi-year durability from a single dose, to deliver large genetic payloads, including multiple genes, to specific tissues, and to allow titration and redosing to adjust or extend expression levels in each patient. The company’s non-viral platform incorporates a novel DNA construct called closed-ended DNA, or ceDNA; a unique cell-targeted lipid nanoparticle delivery system, or ctLNP; and a highly scalable capsid-free manufacturing process that uses its proprietary cell-free rapid enzymatic synthesis, or RES, to produce ceDNA. Generation Bio is innovating genetic medicines to provide durable, redosable treatments for people living with rare and prevalent diseases.
Flow Cytometry Contractor
Company: Prime Medicine
Location: Cambridge
Posted Aug 02, 2023
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, age, sexual orientation, gender identity, disability, veteran status, or any other classification protected by law. The candidate will collaborate with scientists across multiple project teams to provide critical, on-site, scientific and operational flow cytometry support.Primary responsibilities:Perform flow cytometry-based multi-parameter cell sorting and analysis including instrument set-up, compensation control preparation, PMT voltage adjustments, experimental settings selection, sample collection (sorting), troubleshooting, and cleaning.Participate in upstream sample processing for flow cytometry analysis and sorting, including tissue dissociation and antibody staining of cells.Perform maintenance on and schedule service for all flow cytometry analyzers and sorters.Serve as a resource for users; help scientists solve problems with their instrument operations and improve their skills in all aspects of FACS instrument function.Participate in generating, validating, and updating standard operating procedures for use of all flow cytometry instrumentation.Become familiar with relevant software used in the facility and assist facility users in learning to use this software.Respond to queries, communications, and workflows to ensure consistency and timely resolution.Manage inventory for materials, reagents, and consumables for flow cytometry core facility.Maintain detailed documentation of experiments in ELN system.Qualifications:BS 6+, MS 5+, PhD 1-4+ years of relevant research experience3+ years of experience with one or more of the following instrumentation systems: BD Aria/Fusion, BD Symphony, LSR, or Fortessa, Sony MA900 or SH800, Agilent Quanteon, Thermo Fisher Attune; Flow cytometry core experience preferred.Sufficiently high knowledge of flow cytometry and sorting theory and applications to train new users and assist in troubleshooting.Expertise in designing complex flow cytometry antibody panels with appropriate standards and controls, performing complex sorts on rare cell populations, analyzing and interpreting complex data setsExperience with biological cell sample processing relevant to flow cytometry, including working with whole blood, cell lines, and dissociated tissues.Familiar with techniques and instruments for mechanical and enzymatic tissue dissociation.Experience collaborating on cross-functional teams, willingness to roll-up-sleeves to get things done.Must be able to work in a laboratory, controlled environments requiring personal protective equipment (e.g., lab coat, safety glasses, etc.) For more information, please visit www.primemedicine.com.Position Overview:We are currently seeking a motivated, independent, and experienced research associate or associate scientist to join and contribute to a multidisciplinary program team focused on developing novel engineered prime edited ex vivo cell and in vivo therapies. Over time, the Company intends to maximize Prime Editing’s therapeutic potential and advance potentially curative therapeutic options to patients for a broad spectrum of diseases. The Company is leveraging its proprietary Prime Editing platform, a versatile, precise and efficient gene editing technology, to develop a new class of differentiated, one-time, potentially curative genetic therapies. in laboratory. Job pace may be fast and job completion demands may be high. Must be able to remain in a stationary position more than 25% of the time.Prime Medicine is proud to be an equal opportunity employer. Prime Medicine is currently progressing a diversified portfolio of eighteen programs initially focused on genetic diseases with a fast, direct path to treating patients or with a high unmet need because they cannot be treated using other gene-editing approaches. Designed to make only the right edit at the right position within a gene while minimizing unwanted DNA modifications, Prime Editors have the potential to repair almost all types of genetic mutations and work in many different tissues, organs and cell types. Company Overview:Prime Medicine is a leading biotechnology company dedicated to creating and delivering the next generation of gene editing therapies to patients.
Scientist I/II, Neuroscience
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 02, 2023
In this position, you will independently design and execute rodent in vivo experiments to support Development Candidate nomination following the in vitro target identification. Lastly, the Scientist I/II will bring their ex vivo expertise to process the tissues from the in vivo studies, likely with assays such as ddPCR, RT-qPCR, binding assays, activity assays, and/or immunohistochemistry.Key Responsibilities:Design, execute experiments, analyze data, and write reports (both written and verbal) for AAV platform discovery research.Perform cell culture for multiple cell lines to support in vitro target engagement.Conduct analysis including various DNA, mRNA and protein assays from both tissue and cell culture.Design and execute rodent in vivo experiments.Conducts ex vivo tissue, CSF and serum analysis (ELISA, western blot, RT-qPCR, etc. Strong background in cell culture, in vivo experimental methods, and readouts.Hands-on experience with molecular and cellular techniques including ELISA, RT-qPCR, ddPCR, and biochemical assay development.Outstanding problem-solving skillsAbility to read and interpret the literature to support advancement of programs and/or platform discovery research.Ability to be highly productive in a fluid and fast-paced work environment.Good communication skills and ability to multi-task.Ability to analyze and present data independently to the research teams.Strong commitment to accountability for completion of projects in accordance with team and company plans.Excellent organizational skill and attention to detail.Ability to thrive in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.Preferred ExperiencesStrong preference for a candidate with experience in AAV gene therapyPrior related experience, ideally with a biotechnology or other life sciences company, is preferred but not required.Prior experience in drug discovery for neurodegenerative diseases would be preferred. The individual will have the ability to work independently in the laboratory and be responsible for experimental execution of research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. The ideal candidate would have the ability to independently conduct both in vitro, in vivo and ex vivo studies/analysis.The Scientist I/II will support target validation using cell culture with RT-qPCR, ddPCR, binding assays such as Octet/Biacore, activity assays, western blot and/or immunocytochemistry as readouts. )Performs data analyses independently as well as delivers effective data presentations to the research teams.Ensures maintenance of industry-quality records to provide documentation.QualificationsA PhD degree with 0-2+ years, MS with 7+ years or BS with 8+ years’ experience in the field of Neuroscience, Pharmacology or related discipline is required. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. This is an ideal position for an individual with hands-on experience supporting programs from in vitro target validation to in vivo development candidate nomination who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. For more information, visit www.voyagertherapeutics.comJob Summary:We are seeking a highly motivated Scientist I/II to contribute to our Neuroscience team at our facility in Cambridge, Massachusetts. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints.
Scientist/Senior Scientist, Translational Research (Pharmacological Sciences)
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 08, 2023
This is a primarily on-site role with frequent travel to study sites (10-15%).ResponsibilitiesContribute to experimental design, execution, and data analysis for preclinical studies that support Voyager’s capsid engineering platform and therapeutic programs.Serve as a study monitor to review study protocols and address requests/questions from external collaborators and CROsCoordinate with capsid discover team, therapeutic program leads, and operations to set up studies aligned with project requirements and timelines.Monitor study progress and coordinate study activities, such as shipping and receiving of test article and tissue samplesTravel and monitor in-life studies at CRO sites and report site-visit results to Voyager teamsMaintain and update key events in study log and database and timely communicate study status to program teamsReview study report, perform data analysis, and present study results as needed RequirementsAn advanced scientific degree (DVM / PhD) degree in Pharmacology, Biology, or a relevant discipline, with a minimum of 2 years of relevant experience OR a Master’s degree with 5+ years of experience OR a Bachelor’s degree with 8+ years of experienceExperience working with animals is requiredFamiliarity with in vivo techniques, preferably hands-on experience Competency with database, spreadsheet, and presentation applications (e.g., Excel, PowerPoint, Smartsheet, Data entry systems, or similar)Skilled in data analysis using statistical software such as GraphPad Prism, JMP, etc.Outstanding problem-solving skills and ability to multi-task is required.Experience with pharmacology / toxicology study protocol generation, study design, and writing / editing study reports Self-motivated, able to work independently and with team members, highly organized with strong attention to details, and willingness to travel to CRO sitesPreferred qualifications / experienceManagement and / or execution of animal studies at a CRO environment is a plusUnderstanding of relevant biostatistical principles for analysis of animal study dataFamiliarity with bioanalytical and molecular biological techniquesFamiliarity with clinical trials for biologics developmentPrior experience in neuroscience and knowledge of neuroanatomy This is an ideal position for a candidate with a strong background and hands-on experience in preclinical studies, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.The candidate will contribute to the design and execution of various pharmacology and toxicology studies to support development of novel capsids and biotherapeutics such as AAV-based gene therapy. The Scientist will interact with cross-functional capsid discovery and research program teams to execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies using AAV-based gene therapy approaches. The successful candidate will work with our multidisciplinary team in Cambridge, Massachusetts. Voyager’s pipeline includes preclinical programs in Parkinson’s disease, Alzheimer’s disease, and amyotrophic lateral sclerosis (ALS), each with validated targets and biomarkers to enable a path to rapid potential proof-of-biology. The candidate will also perform quality control and analyze study data and communicate study progress through presentations and written reports. This platform is fueling alliances with Pfizer Inc., Novartis and Neurocrine Biosciences as well as multiple programs in Voyager’s own pipeline. For more information, visit www.voyagertherapeutics.comJob SummaryVoyager Therapeutics is growing and seeking an experienced and highly motivated Scientist/Senior Scientist to join our Pharmacological Sciences team who shares our passion for the promise of gene therapy. Voyager’s TRACER AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging innovative expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints. About VoyagerVoyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology.
Scientist/Senior Scientist, Translational Research (Pharmacological Sciences)
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 08, 2023
This is a primarily on-site role with frequent travel to study sites (10-15%).ResponsibilitiesContribute to experimental design, execution, and data analysis for preclinical studies that support Voyager’s capsid engineering platform and therapeutic programs.Serve as a study monitor to review study protocols and address requests/questions from external collaborators and CROsCoordinate with capsid discover team, therapeutic program leads, and operations to set up studies aligned with project requirements and timelines.Monitor study progress and coordinate study activities, such as shipping and receiving of test article and tissue samplesTravel and monitor in-life studies at CRO sites and report site-visit results to Voyager teamsMaintain and update key events in study log and database and timely communicate study status to program teamsReview study report, perform data analysis, and present study results as needed RequirementsAn advanced scientific degree (DVM / PhD) degree in Pharmacology, Biology, or a relevant discipline, with a minimum of 2 years of relevant experience OR a Master’s degree with 5+ years of experience OR a Bachelor’s degree with 8+ years of experienceExperience working with animals is requiredFamiliarity with in vivo techniques, preferably hands-on experience Competency with database, spreadsheet, and presentation applications (e.g., Excel, PowerPoint, Smartsheet, Data entry systems, or similar)Skilled in data analysis using statistical software such as GraphPad Prism, JMP, etc.Outstanding problem-solving skills and ability to multi-task is required.Experience with pharmacology / toxicology study protocol generation, study design, and writing / editing study reports Self-motivated, able to work independently and with team members, highly organized with strong attention to details, and willingness to travel to CRO sitesPreferred qualifications / experienceManagement and / or execution of animal studies at a CRO environment is a plusUnderstanding of relevant biostatistical principles for analysis of animal study dataFamiliarity with bioanalytical and molecular biological techniquesFamiliarity with clinical trials for biologics developmentPrior experience in neuroscience and knowledge of neuroanatomy For more information, visit www.voyagertherapeutics.com.Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc.Job SummaryVoyager Therapeutics is growing and seeking an experienced and highly motivated Scientist/Senior Scientist to join our Pharmacological Sciences team who shares our passion for the promise of gene therapy. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. This is an ideal position for a candidate with a strong background and hands-on experience in preclinical studies, who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.The candidate will contribute to the design and execution of various pharmacology and toxicology studies to support development of novel capsids and biotherapeutics such as AAV-based gene therapy. The Scientist will interact with cross-functional capsid discovery and research program teams to execute in vivo pharmacology, biodistribution, PK/PD, and toxicology studies using AAV-based gene therapy approaches. The successful candidate will work with our multidisciplinary team in Cambridge, Massachusetts. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. The candidate will also perform quality control and analyze study data and communicate study progress through presentations and written reports. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. About&8239;Voyager Therapeutics Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging cutting-edge expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints.
HR Specialist
Company: TreeHouse Foods
Location: Cambridge
Posted Aug 04, 2023
TreeHouse Use Only: IND1 What You Gain: Competitive compensation and benefits programEnrollment in our wellness and employee assistance programsPaid holidays, vacation, and other competitive paid time off opportunitiesAn inclusive working environment where you can build meaningful work relationships with a diverse group of people Leaders who are invested in supporting your career growthOpportunities to be recognized for outstanding contributions to your team through our employee recognition programs Job Description: Identifies, develops, and shares creative sourcing channels to attract qualified candidates for hourly and entry or mid-level salaried rolesDevelops and enhances existing sourcing tools and methods, including stewarding new social media outreach channels where applicable for hourly recruitmentEstablishes and leverages campus relationships to generate skilled trades talent pipelinesManages recruitment process for assigned hourly and salaried requisitions, including posting job ads, managing requisitions, conducting pre-screening, assessing candidates and making hiring recommendationsProvides an exceptional candidate experience, creating meaningful relationships and a lasting impression Develops strong working relationships with internal stakeholders to understand current and future recruitment needsPartners with targeted sites to develop plant-level recruitment strategies, tools, and orientation/onboarding processesStrengthens internal interviewing capability through the delivery of behavioral-based interview trainingLeverages system generated reports to conduct regular audits and provide relevant reporting on recruitment metricsParticipate on various work teams and strategic projects as requiredOther duties and projects, as assigned Your TreeHouse Foods Career is Just a Click Away! We are investing in talent and creating a performance-based culture where employees can do their best work, directly impacting our mission to make high quality, affordable food for our customers, communities and families. Click on the "Apply" button or go directly to www.treehousefoods.com/careers to let us know you're ready to join our team! At TreeHouse Foods, our commitment to excellence extends beyond our products and revolves around our people. We hope you will consider joining the team and being part of our future. Employee Type: Full time Location: MD Cambridge Job Type: Human Resources General Job Posting Title: HR Specialist About Us: TreeHouse Foods (NYSE: THS) is a leading manufacturer of private label packaged foods and beverages, operating a network of production facilities across the United States and Canada.
Scientist I/II, Neuroscience
Company: Voyager Therapeutics
Location: Cambridge
Posted Aug 02, 2023
In this position, you will independently design and execute rodent in vivo experiments to support Development Candidate nomination following the in vitro target identification. Lastly, the Scientist I/II will bring their ex vivo expertise to process the tissues from the in vivo studies, likely with assays such as ddPCR, RT-qPCR, binding assays, activity assays, and/or immunohistochemistry.Key Responsibilities:Design, execute experiments, analyze data, and write reports (both written and verbal) for AAV platform discovery research.Perform cell culture for multiple cell lines to support in vitro target engagement.Conduct analysis including various DNA, mRNA and protein assays from both tissue and cell culture.Design and execute rodent in vivo experiments.Conducts ex vivo tissue, CSF and serum analysis (ELISA, western blot, RT-qPCR, etc. For more information, visit www.voyagertherapeutics.com.Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc.Job Summary:We are seeking a highly motivated Scientist I/II to contribute to our Neuroscience team at our facility in Cambridge, Massachusetts. Strong background in cell culture, in vivo experimental methods, and readouts.Hands-on experience with molecular and cellular techniques including ELISA, RT-qPCR, ddPCR, and biochemical assay development.Outstanding problem-solving skillsAbility to read and interpret the literature to support advancement of programs and/or platform discovery research.Ability to be highly productive in a fluid and fast-paced work environment.Good communication skills and ability to multi-task.Ability to analyze and present data independently to the research teams.Strong commitment to accountability for completion of projects in accordance with team and company plans.Excellent organizational skill and attention to detail.Ability to thrive in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment.Preferred ExperiencesStrong preference for a candidate with experience in AAV gene therapyPrior related experience, ideally with a biotechnology or other life sciences company, is preferred but not required.Prior experience in drug discovery for neurodegenerative diseases would be preferred. The individual will have the ability to work independently in the laboratory and be responsible for experimental execution of research studies supporting cutting edge therapeutic programs and platform discovery research in neurodegenerative disease areas. The ideal candidate would have the ability to independently conduct both in vitro, in vivo and ex vivo studies/analysis.The Scientist I/II will support target validation using cell culture with RT-qPCR, ddPCR, binding assays such as Octet/Biacore, activity assays, western blot and/or immunocytochemistry as readouts. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. )Performs data analyses independently as well as delivers effective data presentations to the research teams.Ensures maintenance of industry-quality records to provide documentation.QualificationsA PhD degree with 0-2+ years, MS with 7+ years or BS with 8+ years’ experience in the field of Neuroscience, Pharmacology or related discipline is required. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. This is an ideal position for an individual with hands-on experience supporting programs from in vitro target validation to in vivo development candidate nomination who thrives in a team-oriented, fast-paced, and cross-disciplinary start-up biotech environment. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. About&8239;Voyager Therapeutics Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology.