Be Or Bc Jobs in Cambridge
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QC Specialist II
Company: 2seventy bio
Location: Cambridge
Posted Jul 31, 2023
The text is a job description for a QC Specialist II position at 2seventy bio. The role involves supporting commercial-level GMP testing laboratories for instrument and equipment maintenance. The position requires working knowledge of existing controls, supporting the instrument/equipment lifecycle process, authoring SOPs, and executing internal validation/qualification documentation. The company values collaboration, communication, and a passion for addressing unmet medical needs of patients. They have a mandatory COVID-19 vaccination policy.
Senior Manager, Data Operations
Company: Iterative Health
Location: Cambridge
Posted Jul 28, 2023
Iterative Health is a company using AI-based precision medicine in gastroenterology to optimize clinical trials for IBD. They use machine learning and computer vision to analyze endoscopic videos and other data, aiming to establish better endpoints for therapeutic response and disease outcomes. The Senior Manager, Data Operations supports the Data Insights & Scientific Strategy department in collecting and leveraging data from various sources for international expansion. They manage complex datasets, formulate statistical models, leverage real-world data to generate evidence, and work with cross-functional teams to prioritize new developments.
Scientist/Senior Scientist, Bioanalytical Sciences (Immunology)
Company: Voyager Therapeutics
Location: Cambridge
Posted Jul 28, 2023
Voyager Therapeutics is a biotechnology company focused on advancing gene therapy and neurology. Their TRACER AAV capsid discovery platform has produced novel capsids with high target delivery and blood-brain barrier penetration. This platform is driving collaborations with major pharmaceutical companies and fueling multiple programs in Voyager's pipeline, including preclinical programs for Parkinson's disease, Alzheimer's disease, and ALS. Voyager is seeking an experienced Scientist/Senior Scientist to join their Bioanalytical Sciences team, developing immunological and bioanalytical assays for AAV gene therapy studies.
Senior Associate Scientist, LNP Process Sciences
Company: Generation Bio
Location: Cambridge
Posted Jul 26, 2023
Generation Bio is innovating genetic medicines to provide durable, redosable treatments for people living with rare and prevalent diseases. They are seeking a Senior Associate Scientist to conduct manufacturing and process development operations for drug product formulations using lipid nanoparticle platforms.
Technical Writer I
Company: Thermo Fisher Scientific
Location: Cambridge
Posted Jul 28, 2023
The job description is for a Technical Writer I position at Thermo Fisher Scientific. The role involves collaborating with subject matter authorities and technical specialists to develop, author, edit, format, illustrate, update, and build new standard operating procedures and other related documentation. The position requires a Bachelor's Degree or an Associate's Degree/Certificate Program with 1-3 years of industry-related experience.
Associate Scientist II, Analytical Innovation - Drug Product Characterization & Function
Company: 2seventy bio
Location: Cambridge
Posted Aug 02, 2023
2seventy is a biotech company focused on developing cell therapies for cancer. They are looking for a detail-oriented individual with experience in cytometry staining and data analysis to join their team. The role involves using mass cytometry and flow cytometry to study CAR T cells, TCRs, and PBMCs. The company values innovation, collaboration, and a strong work ethic.
Senior Research Associate I/II, Vector Engineering
Company: Voyager Therapeutics
Location: Cambridge
Posted Jul 30, 2023
The candidate will be involved in multiple programs and will have to pivot between assignments on a regular basis.ResponsibilitiesCollaborate with scientists to design AAV-compatible constructs with full optimization of upstream and downstream regulatory sequences, scaffolds, artificial microRNA sequences, codon optimization variants, de-targeting sequences or other designs.Build series of transgene constructs using the most appropriate molecular biology techniques (traditional cloning, Gibson assembly, automatic gene synthesis), and deliver fully validated constructs for downstream analysis.Analyze the efficiency, specificity, or other attributes of transgene constructs in various cell culture and animal modelsMaintain accurate and organized records of transgene constructs and associated results and propertiesRequired qualifications· BA or MA in biology, biochemistry, biomedical engineering, or related field· 4+ years hands-on wet lab experience· Proficiency in molecular cloning design and techniques· Hands-on experience in molecular biology techniques (RNA/DNA isolation, plasmid purification, Western blotting, qPCR, RT-qPCR, ELISA)· Experience with mammalian cell culture techniques· Strong collaborative, organizational, and presentation skills· Ability to document, maintain, and share an organized account of lab work and resultsPreferred qualificationsExperience with AAV vectors For more information, visit www.voyagertherapeutics.com.Voyager Therapeutics® is a registered trademark, and TRACER™ is a trademark, of Voyager Therapeutics, Inc. Job overview: We are looking for a versatile, talented and motivated Senior Research Associate I/II to join the Gene Therapy team to support our RNA interference knock-down programs and overexpression programs. This platform is fueling alliances with Pfizer Inc., Novartis Pharma AG, Neurocrine Biosciences, Inc., and Sangamo Therapeutics, Inc., as well as multiple programs in Voyager’s own pipeline. This will involve design, optimization, AAV vectorization and screening of candidate transgene for both RNA interference and gene re-expression programs such as Huntington’s disease and other targets. Voyager’s pipeline includes wholly owned and collaborative preclinical programs in Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and other diseases of the central nervous system, with a focus on validated targets and biomarkers to enable a path to rapid potential proof-of-biology. The position will emphasize the engineering of multiple constructs including gene expression cassettes, RNA interference cassettes, multicistronic/multitarget transgene conformations, miRNA-Overexpression combined cassettes and other innovative molecular designs. Voyager’s TRACER™ AAV capsid discovery platform has generated novel capsids with high target delivery and blood-brain barrier penetration at low doses, potentially addressing the narrow therapeutic window associated with conventional gene therapy delivery vectors. About&8239;Voyager Therapeutics Voyager Therapeutics (Nasdaq: VYGR) is a biotechnology company dedicated to breaking through barriers in gene therapy and neurology. The potential of both disciplines has been constrained by delivery challenges; Voyager is leveraging cutting-edge expertise in capsid discovery and deep neuropharmacology capabilities to address these constraints.
Associate Scientist I/II, Process Development
Company: Vor Bio
Location: Cambridge
Posted Aug 02, 2023
Vor Bio is seeking an Associate Scientist I/II to join their Process Development team. The role involves developing the manufacturing process for cell therapy products, focusing on gene-edited hematopoietic stem cells. The candidate will perform primary human cell isolation, gene-editing, and culture, write SOPs, analyze data, and present results. Experience in mammalian cell culture, analytical software, and cell therapy product manufacturing is preferred. Vor Bio offers competitive benefits, work-life balance, and a diverse, inclusive environment.
MuleSoft Enterprise Data Engineer
Company: Schrödinger, Inc.
Location: Cambridge
Posted Jul 29, 2023
Schrödinger is seeking a MuleSoft Enterprise Data Engineer for a temporary-to-permanent position in their mission to improve human health and quality of life through advanced computational methods. The role involves working with cloud computing, data management, and software suites. The ideal candidate should have experience in data warehouse technical architectures, cloud environments, and ERP/CRM systems. The company offers competitive salary, stock options, and a wide range of benefits.
Scientist/Senior Scientist, Proteomics
Company: Kronos Bio
Location: Cambridge
Posted Jul 28, 2023
Kronos Bio seeks a proteomics expert in protein-protein interaction mapping at the Scientist/Senior Scientist level to join its drug discovery team located in Cambridge, MA. The applicant is expected to be a highly motivated individual with a strong technical background who works equally well driving projects forward independently and as part of a collaborative, multidisciplinary scientific team.
Stability Specialist II
Company: 2seventy bio
Location: Cambridge
Posted Jul 25, 2023
The text is about the role of a Stability Specialist II at 2seventy bio, where the employee will make an impact by originating stability protocols and reports, coordinate, review, trend, and report stability test data across their early and late-phase oncology portfolio. The team is driven by quality and prioritizes what matters most, with a focus on bringing more patients more time. The employee should have a BS/BA in Biology, Chemistry, or equivalent with 6+ years of experience in a cGMP laboratory, knowledge of cGMPs, USP, and FDA regulations, and experience in authoring stability protocols and data review.
Patent Counsel
Company: Generation Bio
Location: Cambridge
Posted Jul 29, 2023
Generation Bio is a thriving, collaborative community of 165 people with diverse talents, beliefs, and experiences headquartered in Cambridge, Massachusetts. They are seeking a Patent Counsel to help develop and implement IP strategies for their innovative ceDNA platform, lipid nanoparticle delivery systems, and rapidly growing pipelines.