Tech Jobs in SAINT LOUIS, Missouri

49,974 open positions · Updated daily

Saint Louis has become a magnet for tech talent thanks to its blend of cutting‑edge research, a diverse industrial base, and a network of top universities. Companies from AI leaders like C3.ai to health‑tech innovators such as Slyce and biotech giants like Gilead Sciences are expanding their footprints, creating a steady stream of roles that blend software engineering, data science, and product management.

The city’s tech ecosystem spans several key sectors. In addition to AI and health tech, the region hosts a thriving fintech community with firms such as The Money Store and a growing number of manufacturing‑automation startups. Logistics giants like FedEx and Lumen Technologies maintain large engineering teams, while the University of Missouri‑St. Louis and Washington University drive research collaborations that feed the local talent pool.

With a cost of living about 15 % below the national average, Saint Louis offers a high quality of life without the price tag of coastal hubs. Median home prices hover around $200,000, and the average rent for a one‑bedroom apartment is roughly $1,200. Salary transparency is therefore crucial; it lets candidates compare offers against local living costs and negotiate wages that reflect the true value of their work in a city where money stretches further.

Licensed Practical Nurse

Company: Wexford Health Sources

Location: East St. Louis, Illinois

Posted Sep 30, 2024

The text describes a job posting for a Licensed Practical Nurse (LPN) position at Southweyern Correctional Center in East Saint Louis, IL. The job is full-time, from 11p-7a, and offers a competitive wage range of $30 - $33/hour. The LPN will work under the supervision of a Wexford Health manager and clinical supervision from the Director of Nursing, Registered Nurses, Medical Director, and/or IDOC personnel. The role involves assisting in the delivery of patient care through the nursing process and guiding patient teaching activities. Wexford Health offers a competitive benefits package including annual increase, up to 40 total paid days off per year, 401(k) plan with 50% match, and Medical, Dental and Vision insurance. The job requirements include being currently licensed as an LPN in the state of Illinois, having current CPR certification, graduating from an accredited School of Nursing, and having one year of clinical experience preferred.

Respiratory Therapist - Full Time, Nights, Mercy South

Company: Mercy

Location: Sappington, Missouri

Posted Sep 30, 2024

Mercy Hospital South is offering a full-time night shift Respiratory Therapist position with a sign-on bonus and loan forgiveness. The Respiratory Therapist will perform direct patient care, consult with physicians, and maintain life support equipment. Mercy values compassionate care, professionalism, and a positive outlook. They offer great benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. The position is safety-sensitive, requiring constant alertness and safe work practices.

Ultrasound Technologist Per Diem

Company: Mercy

Location: Saint Louis, Missouri

Posted Oct 01, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a top workplace. The role involves performing ultrasound procedures independently, requiring proficiency in ultrasound equipment and computers. Mercy provides comprehensive benefits and encourages professional growth. They seek candidates with a positive outlook, strong advocacy, and a commitment to delivering excellent care.

Radiologic Technologist II - FT - Loan Repay Assistance

Company: Mercy

Location: Springfield, Missouri

Posted Oct 01, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer career opportunities tailored to individual skills and talents, and have been recognized as a top workplace by Modern Healthcare Magazine. Mercy provides incentives such as a Loan Repayment Assistance Program up to $20,000 for eligible Imaging co-workers. The role involves assisting radiologists in interventional and special procedures, providing patient care, and potentially performing surgery procedures. Qualifications include a successful completion of an accredited Radiography program, state licensure, 2+ years of relevant experience, and A.R.R.T. registration. Mercy also offers comprehensive benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and employer-matched retirement funds.

RN - Neuro Trauma Intermediate PCU Part Time Weekend Nights

Company: Mercy

Location: Springfield, Missouri

Posted Oct 01, 2024

The text describes a job opportunity for a registered nurse in a Progressive Care Unit (6D) at Mercy. The unit provides high acuity care to critically ill patients and offers a team-oriented, fulfilling work environment. The job comes with various incentives such as sign-on bonuses, education assistance, retirement funds, and comprehensive insurance. The unit works closely with the Cardiovascular PCU and offers learning opportunities and career path programs. The qualifications include a degree from an accredited nursing program, a current RN license, and Basic Life Support certification.

Senior Insurance Advisor

Company: Herself

Location: Minneapolis–Saint Paul, MN

Posted Sep 30, 2024

Herself Health is seeking a Senior Insurance Advisor to join their team. The role involves ensuring an excellent patient experience, increasing patient satisfaction, and improving the efficiency and effectiveness of the healthcare organization.

Respiratory Therapist - 3-12s, Nights, Mercy St. Louis

Company: Mercy

Location: Creve Coeur, Missouri

Posted Sep 30, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and heart, and have been recognized as a top place to work. Mercy provides a range of benefits including health, vision, and dental coverage, PTO, tuition reimbursement, and retirement funds. They are expanding and offer opportunities for innovation and career growth. The Respiratory Loan Repayment Assistance Program provides financial support to eligible co-workers. Qualifications include a degree from a CoArc approved Respiratory Care program, state licensure, RRT credential, and PALS certification for ER co-workers.

Heavy Mobile Equipment Repairer

Company: Department of the Army - Army Tank-Automotive and Armament Command (TACOM)

Location: Fort Leonard Wood, Missouri Fort Leonard Wood, Missouri

Posted Sep 30, 2024

The job posting is for a field level maintenance position that requires experience with heavy duty equipment and commercial vehicles. The posting also mentions a direct hire authority and the competitive service.

Cardiothoracic Surgeon

Company: Department of Veterans Affairs - Veterans Health Administration

Location: Columbia, Missouri Columbia, Missouri

Posted Sep 30, 2024

Harry S Truman VAMC is seeking a Cardiothoracic Surgeon to work in Columbia, MO. Columbia offers a wide variety of recreation options and a great place to work and live.

Respiratory Therapist - Nights, Mercy South

Company: Mercy

Location: Sappington, Missouri

Posted Sep 30, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and talents, and provide benefits such as day-one comprehensive health coverage, PTO, tuition reimbursement, and retirement funds. They are currently offering a sign-on bonus and a loan repayment assistance program for respiratory therapists. The role involves direct patient care, ventilator support, and maintaining life support equipment. Qualifications include a high school diploma, successful completion of a program approved by the National Board for Respiratory Care, licensure in Missouri, minimum 1 year experience, and registration as a therapist by the National Board of Respiratory Care. BLS/CPR certification is also required.

Clinical Pharmacist - St. Louis Hospital - Infusion - FT/Float

Company: Mercy

Location: Saint Louis, Missouri

Posted Oct 01, 2024

Mercy is a healthcare organization that values compassionate care and exceptional service. They offer careers that align with individual skills and hearts, and have been recognized as a top workplace. The role involves working with healthcare teams to provide safe drug therapy and serving as a drug information resource. Mercy provides great benefits including health coverage, PTO, tuition reimbursement, and retirement funds. They are committed to innovation and expanding to better serve communities.

Inside Sales Account Manger

Company: Paladin Technologies

Location: Minneapolis–Saint Paul, MN

Posted Sep 30, 2024

Paladin Technologies is a leading complex systems integrator in North America, providing services such as design, deployment, optimization, and maintenance of communication and digital networks. The company is looking for an Inside Sales Representative to work closely with the team to ensure high-quality service to customers.

Frequently Asked Questions

What types of tech jobs are available in Saint Louis?
Saint Louis offers a wide range of tech roles, from Software Engineer and Data Scientist to DevOps Engineer, Product Manager, UI/UX Designer, Cybersecurity Analyst, Mobile Developer, and Cloud Engineer. Companies such as C3.ai, Slyce, Gilead Sciences, FedEx, and Lumen Technologies hire for these positions, as do local fintech startups, manufacturing‑automation firms, and logistics tech teams.
Are tech roles in Saint Louis remote or on-site?
Many tech positions in Saint Louis blend remote and on‑site work. Established firms like Amazon and FedEx offer hybrid schedules, while startups such as Slyce often provide fully remote options. On‑site roles remain common for teams that prioritize collaboration, especially in research labs and manufacturing plants.
Who are the major employers for tech talent in Saint Louis?
Key employers in the region include C3.ai, Slyce, Gilead Sciences, FedEx, Lumen Technologies, Amazon, Google (regional office), the University of Missouri‑St. Louis, Washington University, and St. Louis Children’s Hospital. These organizations drive most of the tech hiring in the city.
What are the salary expectations for tech roles in Saint Louis?
Typical salary ranges in Saint Louis are: Software Engineer $75k–$120k, Senior Software Engineer $100k–$150k, Data Scientist $80k–$130k, Product Manager $90k–$140k, and DevOps Engineer $85k–$130k. The median tech salary hovers around $95k, but exact figures vary by experience, specialization, and company size.
What advice should I follow when relocating to Saint Louis for tech work?
Research local neighborhoods such as Clayton, University City, and Laclede’s Hill for housing and commute options. Leverage salary data on JobTransparency to negotiate competitive offers. Attend local meetups like St. Louis Tech Meetup and C3.ai events to build a network. Consider public transit, bike lanes, and parking when choosing a home. Finally, review relocation packages offered by employers and factor in the city’s lower cost of living to maximize your net income.

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