Tech Jobs in Cambridge

5,798 open positions · Updated daily

Cambridge's tech scene thrives at the intersection of world‑class research institutions like MIT and Harvard, a dense network of venture capital, and a culture that nurtures startups. The city attracts talent in AI, data science, and cybersecurity, driving demand for software engineers, machine learning specialists, and product managers.

Cambridge hosts a diverse roster of tech firms—from global pharma leaders such as Gilead Sciences and Boston Scientific to cloud‑native companies like HubSpot and Wayfair. Start‑ups like Ginkgo Bioworks, Butterfly Network, and Clari focus on biotech innovation, while IBM Research and MIT Lincoln Laboratory push the frontier of quantum computing and secure communications. This mix creates opportunities across hardware, software, fintech, and biotech sectors.

While the median rent for a one‑bedroom apartment in Cambridge tops $3,000/month and the city’s overall cost index is high, salaries often exceed national averages. Transparent salary data on Job Transparency allows candidates to benchmark offers, negotiate effectively, and align compensation with the true value of living in a high‑cost market.

Principal Associate Scientist I

Company: 2seventy bio

Location: Cambridge

Posted Feb 09, 2023

At 2seventy, you can make a significant impact by managing Illumina sequencers, developing new sequencing protocols, and serving as a subject matter expert on NGS activities. The team is part of the Translational Biomarkers department, and the role requires a Master's degree in Molecular Biology, Biotechnology, or a related field with 3 years of experience in Illumina sequencing technologies, troubleshooting, and working in a fast-paced lab environment.

Sr. Accountant

Company: Inari

Location: Cambridge

Posted Feb 10, 2023

Inari, a SEEDesign company, is seeking a Senior Accountant to join their growing Finance team. The role involves preparing GAAP and operating financial results, assisting in month-end, quarter-end, and year-end accounting close, and managing balance sheet account reconciliations. The ideal candidate will have a Bachelor's degree in Accounting, 3-5 years of experience, and a strong understanding of U.S. GAAP accounting and financial reporting. Prior experience with NetSuite or an equal-caliber ERP system is preferred. The candidate should possess strong analytical skills, attention to detail, and the ability to work independently and collaboratively.

Senior Paralegal

Company: Inari

Location: Cambridge

Posted Feb 10, 2023

Inari is a diversity and complexity-embracing company using predictive design and advanced multiplex gene editing to develop step-change products, taking a nature positive approach to transform the food system. They have over 270 employees, with research sites in Cambridge, MA (USA) and Ghent (Belgium), and aim to be part of a diverse and inclusive team developing unique solutions to feed the world while protecting the planet's natural resources. They are looking for a Senior Paralegal to assist with documents management, maintaining corporate records and files, managing contracts, and coordinating work with the legal team and another paralegal. The role requires a Bachelor's degree, paralegal certificate, at least 10 years of corporate or law firm paralegal experience, and strong organization, attention to detail, and communication skills.

Research Associate/Senior Research Associate

Company: Voyager Therapeutics

Location: Cambridge

Posted Feb 04, 2023

Voyager Therapeutics is a biotech company that is developing gene therapy using AAV capsid discovery platform. They are seeking a Research Associate to contribute to their Assay Development team. The successful candidate will develop and optimize biochemical assays and participate in the development of pharmacodynamic effects in various tissues.

Scientist/Sr. Scientist, Genome Editing

Company: Inari

Location: Cambridge

Posted Feb 10, 2023

Inari, a SEEDesign company, is seeking a Ph.D. scientist or senior scientist with expertise in genome editing and DNA repair. The role involves leading or participating in scientific projects, developing and optimizing gene editing tools for crop species, and communicating results to various stakeholders. Inari values a diverse and inclusive team, combining agriculture industry expertise with innovative minds from various fields. The ideal candidate will have a strong track record in tackling complex problems, demonstrating creative and strategic thinking, and possessing excellent organizational skills.

Computational Scientist

Company: MOMA Therapeutics

Location: Cambridge

Posted Feb 07, 2023

MOMA Therapeutics is seeking a Computational Scientist to join their team. The successful candidate will work with a resilient and collaborative group dedicated to discovering transformative medicines for patients. The role involves developing computational methods for studying dynamic proteins, implementing computational chemistry workflows, and collaborating with various functions to achieve corporate goals. The ideal candidate will have a PhD in physics, computational chemistry, or related field, strong understanding of computational biophysical approaches, proficiency in Python and data science ecosystem, and experience in a cloud environment and distributed compute. MOMA Therapeutics is an equal opportunity employer.

Education, Learning and Training (ELT) Specialist

Company: Changeis, Inc.

Location: Cambridge

Posted Feb 04, 2023

Changeis, Inc. is an award-winning 8(a) certified, woman-owned small business that provides management consulting and engineering services to the public sector. The company has a strong track record of successful programmatic initiatives, acquisition-sensitive deliverables, and strategic priorities. They offer a full benefit package and are currently seeking an Education, Learning & Training (ELT) Specialist to join their team.

General Manager, STM

Company: SmarterTravel

Location: Cambridge

Posted Feb 01, 2023

The General Manager of STM is responsible for owning the P&L for SmarterTravel's content and metasearch sites, coordinating and directing an editorial and engineering team, and driving strategy around cross connections with SmarterTravel's hotels product. The GM is expected to define a vision and strategy for STM teams, translate it into a tangible execution plan, and maintain tracking of progress towards goals. The role requires a deep knowledge of digital content publishing best practices, SEO, and audience development tactics.

Senior Associate Data Scientist II

Company: 2seventy bio

Location: Cambridge

Posted Feb 09, 2023

2seventy is a company that focuses on using time effectively for meaningful work and improving patient care. They are looking for a Data Science candidate with a Master's degree in a related field and four years of experience in data science or bioinformatics. The role involves working on computational production pipelines, data repositories, and visualization/analysis applications for multiple stages of drug development. The company has a mandatory COVID-19 vaccination policy.

Senior Associate Scientist I

Company: 2seventy bio

Location: Cambridge

Posted Feb 09, 2023

2seventy is seeking a Technical Development Operations team member to contribute to the development and characterization of manufacturing processes for T-cell-based therapies. The role requires a Master's degree in Cell Biology, Bioengineering, Immunology, or a related field, along with two years of experience in the cell therapy industry. The successful candidate will be responsible for laboratory experiments, authoring and maintaining records, and representing the team in discussions with external collaborators. The company has a mandatory COVID-19 vaccination policy.

Scientist/Sr.Scientist, Translational Research

Company: Voyager Therapeutics

Location: Cambridge

Posted Feb 04, 2023

Voyager Therapeutics, a pre-clinical stage biotech, is seeking a highly motivated and experienced Scientist / Senior Scientist to join their Bioanalytical Assay Development team in Cambridge, Massachusetts. The ideal candidate will have a strong background in Ligand Binding Assay (LBA) methodologies and will be responsible for developing, optimizing, and transferring biomarker, immunogenicity, PK, and biochemical assays. The role involves working in a fast-paced environment, collaborating with internal research teams, and independently analyzing and interpreting data. Essential qualifications include a Bachelor's or Master's degree in Molecular/Cellular Biology, Biochemistry, Pharmacology, or a similar field with 5+ years of relevant hands-on experience or a PhD with a minimum of 2 years experience in biotechnology industry. Deep expertise and extensive hands-on experience in diverse LBA platforms, protein and antibody chemistry, and excellent critical thinking and problem-solving skills are required. Preferred experiences include managing bioanalytical work at CRO labs, proficiency with Excel, SoftMax Pro, GraphPad Prism, JMP, familiarity with mass spectrophotometry methods, understanding of statistical principles, and familiarity with clinical trials for biologics development.

Senior Manager SEC Reporting

Company: Kronos Bio

Location: Cambridge

Posted Feb 09, 2023

The role involves managing the monthly close process, supporting financial reporting, and overseeing activities of senior accountants and bookkeepers. The candidate should have a Bachelor's degree in Accounting, 5-7 years of relevant experience, strong financial analysis skills, and proficiency in Microsoft Excel. They must be independently motivated, detail-oriented, and have excellent communication skills.

Frequently Asked Questions

What types of tech jobs are available in Cambridge?
Software engineer, data scientist, machine learning engineer, product manager, cybersecurity analyst, bioinformatics specialist, hardware design engineer, research scientist, and full‑stack developer.
Are tech roles in Cambridge remote or on‑site?
Most companies offer hybrid models; HubSpot and Wayfair provide remote flexibility, while biotech and hardware roles often require on‑site lab or office presence.
Who are the major tech employers in the Cambridge area?
Gilead Sciences, Boston Scientific, HubSpot, Wayfair, IBM Research, Ginkgo Bioworks, Butterfly Network, MIT Lincoln Laboratory, and numerous AI start‑ups.
What are typical salary expectations for tech roles in Cambridge?
Software engineers average $120k–$180k, data scientists $140k–$200k, senior product managers $160k–$220k, with equity and bonuses common across the region.
What advice should I follow when relocating to Cambridge for tech work?
Research neighborhoods like Cambridgeport for walkability, budget for high rents, use public transit (Red Line), network at MIT, Harvard, and local meetups, and leverage salary‑transparent job boards to negotiate offers.

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